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View Structure Prediction Details

Protein: MIG3
Organism: Saccharomyces cerevisiae
Length: 394 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIG3.

Description E-value Query
Range
Subject
Range
gi|18916833 - gi|18916833|dbj|BAB85555.1| KIAA1969 protein [Homo sapiens]
0.0 [2..279] [264..557]
Z287_MOUSE, ZN28... - Zinc finger protein 287 OS=Mus musculus GN=Znf287 PE=2 SV=1, (Q9EQB9) Zinc finger protein 287 (Zfp-2...
0.0 [1..278] [406..671]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYLRDRFPP DNDQRPFRCE ICSRGFHRLE HKKRHGRTHT GEKPHKCTVQ GCPKSFSRSD  60
   61 ELKRHLRTHT KGVQRRRIKS KGSRKTVVNT ATAAPTTFNE NTGVSLTGIG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 130.522879
Match: 1lu6A_
Description: No description for 1lu6A_ was found.

Predicted Domain #2
Region A:
Residues: [111-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSKVPPILIS VAQNCDDVNI RNTGNNNGIV ETQAPAILVP VINIPNDPHP IPSSLSTTSI  60
   61 TSIASVYPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1bbo__
Description: Enhancer binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [180-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSPFQYLKSG FPEDPASTPY VHSSGSSLAL GELSSNSSIF SKSRRNLAAM SGPDSLSSSK  60
   61 NQSSASLLSQ TSHPSKSFSR PPTDLSPLRR IMPSVNTGDM EISRTVSVSS SS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.456 0.266 specific transcriptional repressor activity a.1.1 Globin-like
View Download 0.251 0.140 specific transcriptional repressor activity a.3.1 Cytochrome c
View Download 0.406 0.047 specific transcriptional repressor activity d.109.1 Actin depolymerizing proteins
View Download 0.291 0.005 specific transcriptional repressor activity a.24.17 Group V grass pollen allergen

Predicted Domain #4
Region A:
Residues: [292-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSLTSVTYDD TAAKDMGMGI FFDRPPVTQK ACRSNHKYKV NAVSRGRQHE RAQFHISGDD  60
   61 EDSNVHRQES RASNTSPNVS LPPIKSILRQ IDNFNSAPSY FSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.321 d.58.7 RNA-binding domain, RBD
View Download 0.504 b.40.2 Bacterial enterotoxins
View Download 0.359 a.4.12 TrpR-like
View Download 0.634 d.233.1 Inhibitor of vertebrate lysozyme, Ivy
View Download 0.297 d.140.1 Ribosomal protein S8
View Download 0.295 d.95.2 Homing endonucleases
View Download 0.294 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.273 d.89.1 Origin of replication-binding domain, RBD-like
View Download 0.262 b.40.4 Nucleic acid-binding proteins
View Download 0.250 c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.246 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.227 d.95.2 Homing endonucleases
View Download 0.217 d.64.1 eIF1-like
View Download 0.206 d.58.7 RNA-binding domain, RBD


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle