YRC Public Data Repository - Protein Structure Prediction

Protein:	UBC8
Organism:	Saccharomyces cerevisiae
Length:	218 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBC8.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-57	[4..148]	[2..147]
gi\|209154446, gi... - gi\|209731988\|gb\|ACI66863.1\| Ubiquitin-conjugating enzyme E2 D2 [Salmo salar], gi\|209154446\|gb\|ACI334... UB2D2_RAT - Ubiquitin-conjugating enzyme E2 D2 OS=Rattus norvegicus GN=Ube2d2 PE=1 SV=1 UB2D2_XENLA - Ubiquitin-conjugating enzyme E2 D2 OS=Xenopus laevis GN=ube2d2 PE=1 SV=1 tr\|U3KNK3\|U3KNK3... - Uncharacterized protein OS=Oryctolagus cuniculus GN=UBE2D2 PE=3 SV=1 UB2D2_MOUSE - Ubiquitin-conjugating enzyme E2 D2 OS=Mus musculus GN=Ube2d2 PE=1 SV=1 gi\|55624938 - gi\|55624938\|ref\|XP_517968.1\| PREDICTED: similar to ubiquitin conjugating enzyme isoform 5 [Pan trogl... UBE2D2 - ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) gi\|62859579, gi\|... - gi\|89269841\|emb\|CAJ81618.1\| ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) [Xenopus trop... UB2D2_BOVIN - Ubiquitin-conjugating enzyme E2 D2 OS=Bos taurus GN=UBE2D2 PE=2 SV=1 gi\|73949228, gi\|... - gi\|73949234\|ref\|XP_855983.1\| PREDICTED: similar to Ubiquitin-conjugating enzyme E2 D2 (Ubiquitin-pro... ENSCJAT00000032834 - null	2.0E-56	[4..148]	[2..147]
gi\|18417097, gi\|... - gi\|66354424\|gb\|AAY44849.1\| ubiquitinating enzyme [Arabidopsis thaliana], gi\|18417097\|ref\|NP_567791.1...	7.0E-56	[4..148]	[32..177]
gi\|456568 - gi\|456568\|gb\|AAA64427.1\| ubiquitin conjugating enzyme	2.0E-55	[4..148]	[2..147]
UBC4_SOLLC - Ubiquitin-conjugating enzyme E2-17 kDa OS=Solanum lycopersicum PE=2 SV=1 gi\|83283973 - gi\|83283973\|gb\|ABC01894.1\| ubiquitin-conjugating enzyme E2-like protein [Solanum tuberosum]	3.0E-55	[4..148]	[2..147]

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Predicted Domain #1

Region A:
Residues: [1-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSKRRIET DVMKLLMSDH QVDLINDSMQ EFHVKFLGPK DTPYENGVWR LHVELPDNYP  60
   61 YKSPSIGFVN KIFHPNIDIA SGSICLDVIN STWSPLYDLI NIVEWMIPGL LKEPNGSDPL 120
  121 NNEAATLQLR DKKLYEEKIK EYIDKYATKE KYQQMFGGDN D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	264.0
Match:	1qcqA_
Description:	Ubiquitin conjugating enzyme, UBC
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [162-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDDSDSGGDL QEEDSDSDED MDGTGVSSGD DSVDELSEDL SDIDVSDDDD YDEVANQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits