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View Structure Prediction Details

Protein: VAB2
Organism: Saccharomyces cerevisiae
Length: 282 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VAB2.

Description E-value Query
Range
Subject
Range
VAB2 - Protein with a potential role in vacuolar function, as suggested by its ability to bind Vac8p; green...
VAB2_YEAST - Biogenesis of lysosome-related organelles complex 1 subunit VAB2 OS=Saccharomyces cerevisiae (strain...
VAB2_YEAS7 - Biogenesis of lysosome-related organelles complex 1 subunit VAB2 OS=Saccharomyces cerevisiae (strain...
0.0 [1..282] [1..282]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVADLTKGIL KWKSRIEFDA VGSSSYYEEL KGLPPLASHK KLTQAAIFNS TKYELLQVKK  60
   61 DILSIYEVVS RDIDEERNQM QQIELQLKKS LKKVEHSYKN VLKQRASTNC INGNDRLLAN 120
  121 AEKKIGSLNE EL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [177-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHKSCPKSII ATSEASIHEN ASPSPLLEHD E

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.03
Match: 1qoyA
Description: Hemolysin E (HlyE, ClyA, SheA)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [133-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ACVNDIVSDI VNNLTALNAN LPKKAQLLKD DSINVAHYPL LFDF

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.03
Match: 1qoyA
Description: Hemolysin E (HlyE, ClyA, SheA)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [208-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPAESINSFY GENELQSDSL APLQTHDDNI SSCKKILPPK FNTTSGPSIE TNFENISADG  60
   61 LTYTKCSLKN SISLT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.541 0.833 protein binding b.1.2 Fibronectin type III


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle