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View Structure Prediction Details

Protein: HLR1
Organism: Saccharomyces cerevisiae
Length: 423 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HLR1.

Description E-value Query
Range
Subject
Range
HLR1_YEAST - Protein HLR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HLR1 PE=1 SV=1
HLR1 - Protein involved in regulation of cell wall composition and integrity and response to osmotic stress...
0.0 [1..423] [1..423]

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Predicted Domain #1
Region A:
Residues: [1-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENLCPPPPS QMKDFSTPPR NRHRHKRSFA ISGDFEFLKQ PASAPVLPSA YDSPTFENTP  60
   61 RRVSGMSVTM PDESQNESAL LNSPSPRFFI SEASTYSSPI KGVPDAIINL DDVLINKPKM 120
  121 CRSHRKTKSV PVKLDEFYSS HKCSSVPELT INEEIDEDDT NPQLLEPVKP LSSTSLSTDM 180
  181 NEDKKMTLKN ARSHNSLKIQ AQKQRYYNSA RYLPLNSEDR ATDPQILTKQ SSVTSLFSSR 240
  241 SITPVSCNIN NAGRINAISG NYLDDVLYDL DTPATTLIQD IDNLQTSINE RVRLSPQSSS 300
  301 IKKYFSKD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [309-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKSVSSFNFQ SQECDMVSFT EDFAHVTSLS SSILDSEKQT DDEEEESIPE EILRGEPLHV  60
   61 YNETSGSDKS VILPTKQKSA PINKDSKHSS TQYEEKSFKK NRKFKIFAKL FCTRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.524 a.11.2 Second domain of FERM
View Download 0.368 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.453 a.24.4 Hemerythrin
View Download 0.500 a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.361 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.331 a.4.3 ARID-like
View Download 0.310 g.44.1 RING/U-box
View Download 0.306 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.299 a.4.12 TrpR-like
View Download 0.291 a.24.11 Bacterial GAP domain
View Download 0.288 a.1.1 Globin-like
View Download 0.278 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.274 a.26.1 4-helical cytokines
View Download 0.265 a.26.1 4-helical cytokines
View Download 0.264 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.256 d.56.1 GroEL-intermediate domain like
View Download 0.255 d.129.1 TATA-box binding protein-like
View Download 0.245 a.74.1 Cyclin-like
View Download 0.245 a.1.1 Globin-like
View Download 0.240 d.221.1 Nuclease A inhibitor (NuiA)
View Download 0.238 a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.214 c.17.1 Caspase-like
View Download 0.214 d.162.1 LDH C-terminal domain-like

Predicted Domain #3
Region A:
Residues: [325-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSFTEDFAHV TSLSSSILDS EKQTDDEEEE SIPEEILRGE PLHVYNETSG SDKSVILPTK  60
   61 QKSAPINKDS KHSSTQYEEK SFKKNRKFKI FAKLFCTRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.524 a.11.2 Second domain of FERM
View Download 0.500 a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.453 a.24.4 Hemerythrin
View Download 0.368 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.361 d.129.2 Phosphoglucomutase, C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle