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View Structure Prediction Details

Protein: AGE1
Organism: Saccharomyces cerevisiae
Length: 482 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGE1.

Description E-value Query
Range
Subject
Range
AGAP7 - ArfGAP with GTPase domain, ankyrin repeat and PH domain 7
346.0 [0..16] [395..261]
gi|109101576 - gi|109101576|ref|XP_001082744.1| PREDICTED: similar to centaurin, gamma 2 isoform 2 isoform 2 [Macac...
345.0 [0..16] [395..348]
gi|80978937 - gi|80978937|ref|NP_001032213.1| centaurin, gamma 2 isoform 2 [Mus musculus]
339.0 [0..16] [395..348]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFYTTDINK NVVPLFSKGT VARTASKAQY PSWCNNALKL TNILLKSLRC KFQTNRCEDD  60
   61 RGFEVYCVIL KSIALLMAAK ESLILLQIPP SLPSGFPFRS PQLSFTYLST RLSGSQHKST 120
  121 HSHHINHQTH PIHSSSSNSN SNNRIPTKTD SS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.30103
Match: 1eazA
Description: Tapp1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [153-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQHTQHFSFA NAGASNRDEL LSIVRKIDKS NLKCCDCGST ATVEWVSINL LCILCIKCSG  60
   61 VHRSLGSHIS KIRSLTLDNF TSLELMHLLQ NNVSNSNVNA IYESNLRNFP VKKITANSDD 120
  121 SERSKFIIDK YQFKKFVIDS NQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 227.27013
Match: 1dcqA
Description: Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [295-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GREASLKSLI KAIHLDSVFM MQRAIAQSKY SLRELTASEK EQNDLNHSSI FQYSLKHYEI  60
   61 VDGTPIFFIT EFLLCNGIHI DNLPKITTNW SPKVLEYWET KLEMYGTFQA VNTSRPRSGP 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 227.27013
Match: 1dcqA
Description: Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [415-482]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLNMHSNVDS ASSYNKKHDL RVNIPERSAS ASKRWSLSSI PKSSQNLMSP TNLLTMHKSL  60
   61 KLAKKDKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle