YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: GIN4
Organism: Saccharomyces cerevisiae
Length: 1142 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GIN4.

Description E-value Query
Range
Subject
Range
GIN4_YEAST - Serine/threonine-protein kinase GIN4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GIN...
GIN4 - Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-depen...
0.0 [1..1142] [1..1142]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [8..881] [10..803]
gi|119594583, gi... - gi|86990439|ref|NP_004945.3| MAP/microtubule affinity-regulating kinase 2 isoform b [Homo sapiens], ...
0.0 [3..654] [4..660]
gi|12313871, gi|... - gi|7595800|gb|AAF64455.1|AF240782_1 ELKL motif kinase 2 long form [Mus musculus], gi|12313871|ref|NP...
0.0 [4..654] [41..713]
MARK2_RAT - Serine/threonine-protein kinase MARK2 OS=Rattus norvegicus GN=Mark2 PE=1 SV=1
0.0 [1..654] [35..691]
par-1-PA - The gene par-1 is referred to in FlyBase by the symbol Dmel\par-1 (CG8201, FBgn0260934). It is a pro...
0.0 [1..654] [235..907]

Back

Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAINGNSIPA IKDNTIGPWK LGETLGLGST GKVQLARNGS TGQEAAVKVI SKAVFNTGNV  60
   61 SGTSIVGSTT PDALPYGIER EIIIMKLLNH PNVLRLYDVW ETNTDLYLVL EYAEK

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [314-371]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSESNSSIDA TILQNLVILW HGRDPEGIKE KLREPGANAE KTLYALLYRF KCDTQKEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 587.9897
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [116-313]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GELFNLLVER GPLPEHEAIR FFRQIIIGVS YCHALGIVHR DLKPENLLLD HKYNIKIADF  60
   61 GMAALETEGK LLETSCGSPH YAAPEIVSGI PYQGFASDVW SCGVILFALL TGRLPFDEED 120
  121 GNIRTLLLKV QKGEFEMPSD DEISREAQDL IRKILTVDPE RRIKTRDILK HPLLQKYPSI 180
  181 RDSKSIRGLP REDTYLTP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 587.9897
Match: 1a06__
Description: Calmodulin-dependent protein kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [372-1142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKQQQVKKRQ SISSVSVSPS KKVSTTPQRR RNRESLISVT SSRKKPISFN KFTASSASSS  60
   61 NLTTPGSSKR LSKNFSSKKK LSTIVNQSSP TPASRNKRAS VINVEKNQKR ASIFSTTKKN 120
  121 KRSSRSIKRM SLIPSMKRES VTTKLMSTYA KLAEDDDWEY IEKETKRTSS NFATLIDEIF 180
  181 EYEKYEQIRK EKEELERKVR EAKAREELER RRRKQEEKER ARKLLEKEDL KRKQEELKKQ 240
  241 IEIDISDLEQ ELSKHKEEKL DGNIRSISAP MENEEKNINH LEVDIDNILR RRNFSLQTRP 300
  301 VSRLDPGIMF SSPTEEVSPV EPKRTENERL TTEKKILETI RRSKFLGSSF NIDKELKLSK 360
  361 MEYPSIIAPQ RLSEERVVSD SNDGYESLIL PKDGNGVSQL KDSTATTAPV SDGRLRKISE 420
  421 IRVPQFTRKS RHFSESNKRL SVLSMYSTKE SFTNLVDILK NGNLDVNNQQ SQRIPTPRSA 480
  481 DDSEFLFETV NEEAEYTGNS SNDERLYDVG DSTIKDKSAL KLNFADRFNG SNEAKQTDNL 540
  541 HLPILPPLNG DNELRKQNSQ EGDQAHPKIK SMIPESGSSS HTEKEEENEE KEEKKPEQHK 600
  601 QEEDQEKREK VVDDMEPPLN KSVQKIREKN AGSQAKDHSK DHLKEHKQDK NTAIGNGSFF 660
  661 RKFSKSSDKT MELYAKISAK QLFNGLEKLL RGWTQYGLKN IKSHPNNLTL TGKLSSDNIF 720
  721 SLRSTLFEVN IYPRGKMSVV QFKKVSGSFK AVKKLVNEVE NVLNKEGVLQ K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [613-690]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EIDISDLEQE LSKHKEEKLD GNIRSISAPM ENEEKNINHL EVDIDNILRR RNFSLQTRPV  60
   61 SRLDPGIMFS SPTEEVSP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.522879
Match: 1ul7A
Description: Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase activity 4.05475891009228 bayes_pls_golite062009
protein serine/threonine kinase activity 3.7974128326421 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 3.59230737331367 bayes_pls_golite062009
kinase activity 3.41737435609334 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 3.2342722637405 bayes_pls_golite062009
binding 2.41732321506551 bayes_pls_golite062009
transferase activity 2.04713540681686 bayes_pls_golite062009
ATP binding 1.44435058039859 bayes_pls_golite062009
adenyl ribonucleotide binding 1.41005152726625 bayes_pls_golite062009
adenyl nucleotide binding 1.38971642420542 bayes_pls_golite062009
ribonucleotide binding 1.16863558166547 bayes_pls_golite062009
purine ribonucleotide binding 1.16859376715941 bayes_pls_golite062009
purine nucleotide binding 1.15633908642115 bayes_pls_golite062009
nucleotide binding 1.14964488472581 bayes_pls_golite062009
catalytic activity 0.836142537655721 bayes_pls_golite062009
protein binding 0.704339182896017 bayes_pls_golite062009
AMP-activated protein kinase activity 0.496765880715405 bayes_pls_golite062009
magnesium ion binding 0.439688030503848 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [691-749]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEPKRTENER LTTEKKILET IRRSKFLGSS FNIDKELKLS KMEYPSIIAP QRLSEERVV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [750-960]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDSNDGYESL ILPKDGNGVS QLKDSTATTA PVSDGRLRKI SEIRVPQFTR KSRHFSESNK  60
   61 RLSVLSMYST KESFTNLVDI LKNGNLDVNN QQSQRIPTPR SADDSEFLFE TVNEEAEYTG 120
  121 NSSNDERLYD VGDSTIKDKS ALKLNFADRF NGSNEAKQTD NLHLPILPPL NGDNELRKQN 180
  181 SQEGDQAHPK IKSMIPESGS SSHTEKEEEN E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [961-1142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKEEKKPEQH KQEEDQEKRE KVVDDMEPPL NKSVQKIREK NAGSQAKDHS KDHLKEHKQD  60
   61 KNTAIGNGSF FRKFSKSSDK TMELYAKISA KQLFNGLEKL LRGWTQYGLK NIKSHPNNLT 120
  121 LTGKLSSDNI FSLRSTLFEV NIYPRGKMSV VQFKKVSGSF KAVKKLVNEV ENVLNKEGVL 180
  181 QK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle