YRC Public Data Repository - Protein Structure Prediction

Protein:	DIG2
Organism:	Saccharomyces cerevisiae
Length:	323 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIG2.

Description	E-value	Query Range	Subject Range
DIG2_YEAST - Down-regulator of invasive growth 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DIG2... DIG2 - Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-sp...	0.0	[1..323]	[1..323]
rsp1 - random septum position protein Rsp1 RSP1_SCHPO - DnaJ-related protein rsp1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rsp1 PE=1 SV=1	7.0E-79	[34..285]	[44..270]

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Predicted Domain #1

Region A:
Residues: [1-323]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKEEQEDPQ QEQISTVQEN DPRNLQQLGM LLVSPGLDED RLSEKMISKI KKSRDIEKNQ  60
   61 KLLISRLSQK EEDHSGKPPT ITTSPAEKTV PFKSLNHSLK RKRVPPALNF SDIQASSHLH 120
  121 GSKSAPPNIT RFPQHKNSLR VRYMGRMAPT NQDYHPSVAN SYMTATYPYP YTGLPPVPCY 180
  181 PYSSTPTQTH AYEGYYSPMY PGPLYNNGII PADYHAKRKK LAGRSPHLED LTSRKRTFVS 240
  241 KHHNGDPIIS KTDEDIECSV TKNSLSEGAS LNDDADDDND KERIIIGEIS LYDDVFKFEV 300
  301 RDDKNDYMKA CETIWTEWHN LKK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [174-323]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPPVPCYPYS STPTQTHAYE GYYSPMYPGP LYNNGIIPAD YHAKRKKLAG RSPHLEDLTS  60
   61 RKRTFVSKHH NGDPIISKTD EDIECSVTKN SLSEGASLND DADDDNDKER IIIGEISLYD 120
  121 DVFKFEVRDD KNDYMKACET IWTEWHNLKK