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View Structure Prediction Details

Protein: YDR444W
Organism: Saccharomyces cerevisiae
Length: 687 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR444W.

Description E-value Query
Range
Subject
Range
gi|207346273 - gi|207346273|gb|EDZ72819.1| YDR444Wp-like protein [Saccharomyces cerevisiae AWRI1631]
YD444_YEAST - Putative lipase YDR444W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDR444W PE=1 SV=...
gi|190404628 - gi|190404628|gb|EDV07895.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
YDR444W - Putative protein of unknown function
gi|151942410 - gi|151942410|gb|EDN60766.1| conserved protein [Saccharomyces cerevisiae YJM789]
0.0 [1..687] [1..687]
YE7A_SCHPO - Putative lipase spac4a8.10 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC4A8.10 PE=2...
SPAC4A8.10 - lipase
0.0 [54..643] [106..689]
gi|28922217, gi|... - gi|32412922|ref|XP_326941.1| predicted protein [Neurospora crassa], gi|28922217|gb|EAA31464.1| conse...
gi|85098994 - gi|85098994|ref|XP_960700.1| hypothetical protein NCU06655 [Neurospora crassa OR74A]
0.0 [194..643] [10..434]
gi|21689821, gi|... - gi|51970748|dbj|BAD44066.1| unnamed protein product [Arabidopsis thaliana], gi|42561882|ref|NP_17246...
2.0E-56 [199..451] [523..749]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-55 [186..459] [67..333]
FAM135A - family with sequence similarity 135, member A
2.0E-55 [167..438] [1229..1458]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYKINRMKN SLEINETGGT LLVDERKRLR IGELYRYKFS VNKDVIKEQG LDVSHLFLRI  60
   61 KNEESALLRP LYLTGPYSFY IDVRPHNYNE NRKFPGKEII PFVENLKPDE RFKVKILLNE 120
  121 NSRVGDTSLY SWTIDIISQL AVTTIPKLEF SFRIGTTRKV VKKSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [166-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLFKSIEGVS LEMWDTETLW DLPPKFPEKP VHLVIMTHGI FSNIGCDMLY MKDKIEEMTF  60
   61 PMDESINPNI IVRGFMGNVG KSGHGIHCLG VRVGKYVLET VDKLNKKYKV DRISFIGHSL 120
  121 GGPTQSMAVR YISIKRPDFF DAVKGVKPVN FITLASPFIG VIGDFPFYLS VPLDMGALGL 180
  181 TGRDLNLKYT PLTSKDGLYA DDEVYPEHSK YILEILPQAP AKKVFESFKR RTIYANVMDD 240
  241 GIVPLRTAAL LYLDWRSIHK VQKIRKKNKN SPTSSEFVSS DSPESS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.69897
Match: 1eh5A_
Description: Palmitoyl protein thioesterase 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.39629727416851 bayes_pls_golite062009
hydrolase activity 1.1444670166202 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.985235528680562 bayes_pls_golite062009
lipase activity 0.849473630399459 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [452-687]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GASSPSNENG NNVGEIPAES PNKKATLQWT LPQAVIHGSK INKYKRGQTN EANSDSDNEQ  60
   61 GVFLDGQKFE PPKEANTVLS ALSVLTAAIP DQEYIKNPAV RKDEVIHDKL YHPEELPPPH 120
  121 YENRPIVKKL IYPNESVNRI QERIAREWQE TMTWRKVLVQ IQPDSHNNIV VRRRFVNLYG 180
  181 YVAVEHMVEH HFGSKVCSEL AEDANEPKDE PNQSSQADRS NEYNEGEISK GAENAT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle