YRC Public Data Repository - Protein Structure Prediction

Protein:	URH1
Organism:	Saccharomyces cerevisiae
Length:	378 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for URH1.

Description	E-value	Query Range	Subject Range
gi\|13472783, gi\|... - gi\|14023530\|dbj\|BAB50136.1\| nucleoside hydrolase [Mesorhizobium loti MAFF303099], gi\|13472783\|ref\|NP...	0.0	[40..370]	[1..312]
gi\|25321080 - pir\|\|AF3520 purine nucleosidase (EC 3.2.2.1) [imported] - Brucella melitensis (strain 16M) gi\|17988432, gi\|... - gi\|17988432\|ref\|NP_541065.1\| inosine-uridine preferring nucleoside hydrolase [Brucella melitensis 16...	1.0E-96	[31..369]	[12..329]
RIHA_ECOLI, YBEK... - (P41409) Hypothetical protein ybeK, Pyrimidine-specific ribonucleoside hydrolase rihA (EC 3.2.-.-) (... RIHA_ECOBW - Pyrimidine-specific ribonucleoside hydrolase RihA OS=Escherichia coli (strain K12 / MC4100 / BW2952)... EG12701 - ribonucleoside hydrolase 1 / Ribonucleoside hydrolase, pyrimidine specific gi\|170080230, gi... - gi\|170080331\|ref\|YP_001729651.1\| ribonucleoside hydrolase 1 [Escherichia coli str. K-12 substr. DH10... gi\|194439885, gi... - gi\|83584753\|ref\|ZP_00923416.1\| COG1957: Inosine-uridine nucleoside N-ribohydrolase [Escherichia coli... gi\|4062271, gi\|8... - gi\|89107520\|ref\|AP_001300.1\| ribonucleoside hydrolase 1 [Escherichia coli str. K-12 substr. W3110], ... gi\|253972630, gi... - gi\|254160729\|ref\|YP_003043837.1\| ribonucleoside hydrolase 1 [Escherichia coli B str. REL606], gi\|253... gi\|253976824, gi... - gi\|254287517\|ref\|YP_003053265.1\| ribonucleoside hydrolase 1 [Escherichia coli BL21(DE3)], gi\|2539768... gi\|242376421, gi... - gi\|251784148\|ref\|YP_002998452.1\| hypothetical protein B21_00606 [Escherichia coli BL21], gi\|24237642... EG12701 - ribonucleoside hydrolase 1 / Ribonucleoside hydrolase, pyrimidine specific	3.0E-94	[45..368]	[4..307]
gi\|168786501, gi... - gi\|189373662\|gb\|EDU92078.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O157:H... gi\|168802439, gi... - gi\|189375581\|gb\|EDU93997.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O157:H... gi\|195939389 - gi\|195939389\|ref\|ZP_03084771.1\| ribonucleoside hydrolase 1 [Escherichia coli O157:H7 str. EC4024] gi\|208725560, gi... - gi\|208805759\|ref\|ZP_03248096.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O1... gi\|208815054, gi... - gi\|208815054\|ref\|ZP_03256233.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O1... gi\|208822967, gi... - gi\|208822967\|ref\|ZP_03263285.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O1... RIHA_ECO5E - Pyrimidine-specific ribonucleoside hydrolase RihA OS=Escherichia coli O157:H7 (strain EC4115 / EHEC)... gi\|217320943, gi... - gi\|217324722\|ref\|ZP_03440806.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O1... gi\|188013882, gi... - gi\|188013882\|gb\|EDU52004.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O157:H... gi\|13360148, gi\|... - gi\|15829944\|ref\|NP_308717.1\| ribonucleoside hydrolase 1 [Escherichia coli O157:H7 str. Sakai], gi\|13... gi\|189354849, gi... - gi\|189354849\|gb\|EDU73268.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O157:H... gi\|189365377, gi... - gi\|189365377\|gb\|EDU83793.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O157:H... gi\|189363460, gi... - gi\|189363460\|gb\|EDU81879.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O157:H... gi\|187767178, gi... - gi\|187767178\|gb\|EDU31022.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O157:H... gi\|168779142, gi... - gi\|189003131\|gb\|EDU72117.1\| inosine-uridine preferring nucleoside hydrolase [Escherichia coli O157:H... gi\|254591215, gi... - gi\|254791815\|ref\|YP_003076652.1\| ribonucleoside hydrolase 1 [Escherichia coli O157:H7 str. TW14359],... RIHA_ECO57 - Pyrimidine-specific ribonucleoside hydrolase RihA OS=Escherichia coli O157:H7 GN=rihA PE=3 SV=1 gi\|209776950, gi... - pir\|\|E85565 probable tRNA synthetase ybeK [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|194417295, gi... - gi\|83569108\|ref\|ZP_00920568.1\| COG1957: Inosine-uridine nucleoside N-ribohydrolase [Shigella dysente... gi\|12513558, gi\|... - gi\|15800365\|ref\|NP_286377.1\| ribonucleoside hydrolase 1 [Escherichia coli O157:H7 EDL933], gi\|125135...	3.0E-94	[45..368]	[4..307]
gi\|84660130, gi\|... - gi\|84660208\|emb\|CAF05944.1\| inosine-uridine preferring nucleoside hydrolase [Leishmania infantum], g... gi\|17813210, gi\|... - gi\|84660242\|emb\|CAF05961.1\| inosine-uridine preferring nucleoside hydrolase [Leishmania donovani], g...	9.0E-94	[43..370]	[2..309]
gi\|15603632, gi\|... - gi\|15603632\|ref\|NP_246706.1\| IunH [Pasteurella multocida subsp. multocida str. Pm70], gi\|12722185\|gb...	4.0E-93	[44..370]	[2..308]
gi\|16759613 - gi\|16759613\|ref\|NP_455230.1\| ribonucleoside hydrolase 1 [Salmonella enterica subsp. enterica serovar... RIHA_SALTI - Pyrimidine-specific ribonucleoside hydrolase rihA OS=Salmonella typhi GN=rihA PE=3 SV=1 RIHA_SALPB - Pyrimidine-specific ribonucleoside hydrolase RihA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / ... gi\|213052446 - gi\|213052446\|ref\|ZP_03345324.1\| ribonucleoside hydrolase 1 [Salmonella enterica subsp. enterica sero... gi\|213425082 - gi\|213425082\|ref\|ZP_03357832.1\| ribonucleoside hydrolase 1 [Salmonella enterica subsp. enterica sero... gi\|213647378 - gi\|213647378\|ref\|ZP_03377431.1\| ribonucleoside hydrolase 1 [Salmonella enterica subsp. enterica sero... RIHA_SALTI - Pyrimidine-specific ribonucleoside hydrolase RihA OS=Salmonella typhi GN=rihA PE=3 SV=1 gi\|29142614, gi\|... - gi\|29142614\|ref\|NP_805956.1\| ribonucleoside hydrolase 1 [Salmonella enterica subsp. enterica serovar... RIHA_SALPB - Pyrimidine-specific ribonucleoside hydrolase rihA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / ... gi\|168264406, gi... - gi\|205347090\|gb\|EDZ33721.1\| inosine-uridine preferring nucleoside hydrolase [Salmonella enterica sub...	4.0E-93	[45..368]	[4..307]
gi\|25321072 - pir\|\|F97404 probable inosine-uridine preferring nucleoside hydrolase (AL355920) [imported] - Agroba... gi\|15155288, gi\|... - gi\|15887725\|ref\|NP_353406.1\| hypothetical protein AGR_C_654 [Agrobacterium tumefaciens str. C58], gi...	7.0E-93	[40..370]	[20..332]
gi\|15073344 - gi\|15073344\|emb\|CAC41852.1\| Inosine-uridine nucleoside N-ribohydrolase [Sinorhizobium meliloti 1021] gi\|15964168 - gi\|15964168\|ref\|NP_384521.1\| putative nucleoside hydrolase protein [Sinorhizobium meliloti 1021]	1.0E-92	[40..370]	[1..313]
RIHA_SALTY - Pyrimidine-specific ribonucleoside hydrolase RihA OS=Salmonella typhimurium (strain LT2 / SGSC1412 /... gi\|167990670, gi... - gi\|205330855\|gb\|EDZ17619.1\| inosine-uridine preferring nucleoside hydrolase [Salmonella enterica sub... RIHA_SALTY - Pyrimidine-specific ribonucleoside hydrolase rihA OS=Salmonella typhimurium GN=rihA PE=3 SV=1 lcl\|NC_016856.1_... - [gene=rihA] [protein=ribonucleoside hydrolase 1] [protein_id=YP_005236376.1] [location=complement(72... RIHA_SALTY - Pyrimidine-specific ribonucleoside hydrolase rihA OS=Salmonella typhimurium GN=rihA PE=3 SV=1	1.0E-92	[45..368]	[4..307]

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Predicted Domain #1

Region A:
Residues: [1-378]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESADFFTSR NLLKQIISLI CKVGEGLDSN NQRLFEEKMT VSKIPIWLDC DPGHDDAIAI  60
   61 LLGCFHPAFN LLGISTCFGN APPENTDYNA RSLLTAMGKA QAIPVYKGAQ RPWKREPHYA 120
  121 PDIHGISGLD GTSLLPKPTF EARTDKTYIE AIEEAILANN GEISFVSTGA LTTLATVFRC 180
  181 KPYLKKSVKY ISIMGGGLHG LGNCNPNLSA EFNVWIDPDA ANYIFRDPDV KDKCIVVPLN 240
  241 LTHKAIATYK VNEMIYNEKN NSKLRELFLE LFQFFAHTYK DMQGFESGPP IHDPVALMPL 300
  301 LEFYGWDPSS AVGFRYKRMD ISCIDDVFNE NSGKIIIEKE YPNDSDVGTI IGLDLNIQYF 360
  361 WDQIFEALNR ADKMSTIG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	419.68867
Match:	1ezrA_
Description:	Nucleoside hydrolase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits