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View Structure Prediction Details

Protein: RVS167
Organism: Saccharomyces cerevisiae
Length: 482 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RVS167.

Description E-value Query
Range
Subject
Range
RVS167 - Actin-associated protein, interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and vi...
RV167_YEAST - Reduced viability upon starvation protein 167 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
gi|190404674 - gi|190404674|gb|EDV07941.1| cytoskeletal protein [Saccharomyces cerevisiae RM11-1a]
2.0E-80 [1..482] [1..482]
gi|119615693, gi... - gi|3064259|gb|AAC39712.1| amphiphysin IIc2 [Homo sapiens], gi|21536413|ref|NP_647599.1| bridging int...
1.0E-76 [3..481] [15..475]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
6.0E-74 [3..481] [15..482]

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Predicted Domain #1
Region A:
Residues: [1-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFKGFTKAV SRAPQSFRQK FKMGEQTEDP VYEDAERRFQ ELEQETKKLS EESKRYSTAV  60
   61 NGMLTHQIGF AKSMEEIFKP ISGKMSDPNA TIPEDNPQGI EASEQYRAIV AELQETLKPD 120
  121 LALVEEKIVT PCQELLKIIT YIRKMATKRN HKKLDLDRHL NTYNKHEKKK EPTAKDEERL 180
  181 YKAQAQVEVA QQEYDYYNDL LKTQLPILFS LEAEFVKPLF VSFYFMQLNI FYTLYNRLQD 240
  241 MKIPYFDLNS DIVESYI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.30103
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [258-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKKGNVEEQT DALTITHFKL GYSKAKLEMT RRKYGVATAE GSPVSGASSG VGYGAGYDPA  60
   61 TATSPTPTGY GYGAAAPSYA AQPAAQYGTA AAVGTAAAVG TAAGAAAGAV PGTYPQYAAA 120
  121 QSPPLTGLGF QQSPQQQQGP PPAYSNPLTS PVAGTPAAAV AAAPGVET

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.82
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [426-482]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTALYDYQAQ AAGDLSFPAG AVIEIVQRTP DVNEWWTGRY NGQQGVFPGN YVQLNKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.39794
Match: 2semA_
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle