YRC Public Data Repository - Protein Structure Prediction

Protein:	ARO10
Organism:	Saccharomyces cerevisiae
Length:	635 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARO10.

Description	E-value	Query Range	Subject Range
gi\|17232105, gi\|... - gi\|17232105\|ref\|NP_488653.1\| acetolactate synthase 3 catalytic subunit [Nostoc sp. PCC 7120], gi\|171... gi\|25291313 - pir\|\|AE2382 acetohydroxy acid synthase [imported] - Nostoc sp. (strain PCC 7120)	0.0	[2..635]	[10..600]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[15..629]	[24..596]
ILVI_BUCAP - Acetolactate synthase large subunit OS=Buchnera aphidicola subsp. Schizaphis graminum GN=ilvI PE=3 S... ILVI_BUCAP - Acetolactate synthase large subunit OS=Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) GN... gi\|3435164 - gi\|3435164\|gb\|AAC32333.1\| acetohydroxy acid synthase large subunit [Buchnera aphidicola]	0.0	[22..634]	[1..568]
gi\|25291271 - pir\|\|A85490 hypothetical protein ilvI [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|12512777, gi\|... - gi\|15799761\|ref\|NP_285773.1\| acetolactate synthase III large subunit [Escherichia coli O157:H7 EDL93...	0.0	[15..629]	[22..594]
gi\|6478282 - gi\|6478282\|gb\|AAF13791.1\|AF129502_2 acetohydroxy acid synthase large subunit [Buchnera aphidicola] ILVI_BUCSC - Acetolactate synthase large subunit OS=Buchnera aphidicola subsp. Schlechtendalia chinensis GN=ilvI ...	0.0	[22..633]	[1..570]
ILVI_BUCAI - Acetolactate synthase large subunit OS=Buchnera aphidicola subsp. Acyrthosiphon pisum GN=ilvI PE=3 S... ILVI_BUCAI - Acetolactate synthase large subunit OS=Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) G... gi\|257471282\|ref... - acetolactate synthase large subunit [Buchnera aphidicola str. LSR1 (Acyrthosiphon pisum)] gi\|25291266 - gi\|25291266\|pir\|\|F84956 acetolactate synthase (EC 4.1.3.18) large chain [imported] - Buchnera sp. (s... gi\|300658818\|emb... - unnamed protein product [Buchnera aphidicola], unnamed protein product [Buchnera aphidicola] gi\|311086541\|gb\|... - acetolactate synthase large subunit [Buchnera aphidicola str. TLW03 (Acyrthosiphon pisum)] gi\|219681597, gi... - gi\|219681597\|ref\|YP_002467983.1\| acetolactate synthase large subunit [Buchnera aphidicola str. 5A (A... gi\|219621887, gi... - gi\|219682154\|ref\|YP_002468538.1\| acetolactate synthase large subunit [Buchnera aphidicola str. Tuc7 ... gi\|311087122\|gb\|... - acetolactate synthase large subunit [Buchnera aphidicola str. JF99 (Acyrthosiphon pisum)]	0.0	[22..634]	[1..568]
Q66EL8\|Q66EL8_YERPS - Acetolactate synthase III, valine sensitive, large subunit FAD and thiamine PPi binding - Yersinia p... gi\|77631655, gi\|... - gi\|77631655\|ref\|ZP_00794241.1\| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate synth... gi\|161511301 - gi\|161511301\|ref\|NP_994917.2\| acetolactate synthase 3 catalytic subunit [Yersinia pestis biovar Micr... gi\|161484748 - gi\|161484748\|ref\|NP_670937.2\| acetolactate synthase 3 catalytic subunit [Yersinia pestis KIM] gi\|186894031, gi... - gi\|186894031\|ref\|YP_001871143.1\| acetolactate synthase 3 catalytic subunit [Yersinia pseudotuberculo... gi\|169752280, gi... - gi\|170025746\|ref\|YP_001722251.1\| acetolactate synthase 3 catalytic subunit [Yersinia pseudotuberculo... gi\|229837069, gi... - gi\|229837069\|ref\|ZP_04457234.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis Pes... gi\|150260425, gi... - gi\|150260425\|ref\|ZP_01917153.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis CA8... gi\|229696794, gi... - gi\|229840428\|ref\|ZP_04460587.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis bio... gi\|229843030, gi... - gi\|229843030\|ref\|ZP_04463180.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis bio... gi\|89104759 - gi\|89104759\|ref\|ZP_01177293.1\| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate synth... gi\|108809551, gi... - gi\|108809551\|ref\|YP_653467.1\| acetolactate synthase 3 catalytic subunit [Yersinia pestis Antiqua], g... gi\|77633509 - gi\|77633509\|ref\|ZP_00795637.1\| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate synth... gi\|229682102, gi... - gi\|229900763\|ref\|ZP_04515887.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis Nep... gi\|25291303 - pir\|\|AI0066 acetolactate synthase (EC 4.1.3.18) isozyme III large chain [imported] - Yersinia pestis... gi\|218927736, gi... - gi\|218927736\|ref\|YP_002345611.1\| acetolactate synthase 3 catalytic subunit [Yersinia pestis CO92], g... gi\|51588307, gi\|... - gi\|51595025\|ref\|YP_069216.1\| acetolactate synthase 3 catalytic subunit [Yersinia pseudotuberculosis ...	0.0	[22..629]	[1..567]
ILVI_HAEIN - Acetolactate synthase large subunit OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 ... ILVI_HAEIN - Acetolactate synthase large subunit OS=Haemophilus influenzae GN=ilvI PE=3 SV=1 gi\|145273548, gi... - gi\|145641734\|ref\|ZP_01797310.1\| acetolactate synthase III large subunit [Haemophilus influenzae R302... gi\|145641734 - gi\|145641734\|ref\|ZP_01797310.1\| acetolactate synthase III large subunit [Haemophilus influenzae R302...	0.0	[22..635]	[1..569]

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Predicted Domain #1

Region A:
Residues: [1-227]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPVTIEKFV NQEERHLVSN RSATIPFGEY IFKRLLSIDT KSVFGVPGDF NLSLLEYLYS  60
   61 PSVESAGLRW VGTCNELNAA YAADGYSRYS NKIGCLITTY GVGELSALNG IAGSFAENVK 120
  121 VLHIVGVAKS IDSRSSNFSD RNLHHLVPQL HDSNFKGPNH KVYHDMVKDR VACSVAYLED 180
  181 IETACDQVDN VIRDIYKYSK PGYIFVPADF ADMSVTCDNL VNVPRIS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	944.0
Match:	1qpbA_
Description:	Pyruvate decarboxylase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [228-403]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQDCIVYPSE NQLSDIINKI TSWIYSSKTP AILGDVLTDR YGVSNFLNKL ICKTGIWNFS  60
   61 TVMGKSVIDE SNPTYMGQYN GKEGLKQVYE HFELCDLVLH FGVDINEINN GHYTFTYKPN 120
  121 AKIIQFHPNY IRLVDTRQGN EQMFKGINFA PILKELYKRI DVSKLSLQYD SNVTQY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	944.0
Match:	1qpbA_
Description:	Pyruvate decarboxylase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [404-635]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNETMRLEDP TNGQSSIITQ VHLQKTMPKF LNPGDVVVCE TGSFQFSVRD FAFPSQLKYI  60
   61 SQGFFLSIGM ALPAALGVGI AMQDHSNAHI NGGNVKEDYK PRLILFEGDG AAQMTIQELS 120
  121 TILKCNIPLE VIIWNNNGYT IERAIMGPTR SYNDVMSWKW TKLFEAFGDF DGKYTNSTLI 180
  181 QCPSKLALKL EELKNSNKRS GIELLEVKLG ELDFPEQLKC MVEAAALKRN KK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	944.0
Match:	1qpbA_
Description:	Pyruvate decarboxylase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits