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View Structure Prediction Details

Protein: VPS74
Organism: Saccharomyces cerevisiae
Length: 345 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VPS74.

Description E-value Query
Range
Subject
Range
VPS74_SCHPO - Vacuolar protein sorting-associated protein 74 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843...
SPAC5D6.13 - Golgi phosphoprotein 3 family
473.0 [0..4] [345..5]
gi|50308107, gi|... - gi|50308107|ref|XP_454054.1| unnamed protein product [Kluyveromyces lactis], gi|49643189|emb|CAG9914...
gi|49643189 - gi|49643189|emb|CAG99141.1| KLLA0E02355p [Kluyveromyces lactis]
461.0 [0..3] [345..2]
gi|49524195 - gi|49524195|emb|CAG57786.1| unnamed protein product [Candida glabrata]
gi|49524195, gi|... - gi|50284931|ref|XP_444893.1| hypothetical protein CAGL0A02926g [Candida glabrata CBS138], gi|4952419...
438.0 [0..1] [345..1]
gi|2281983, gi|7... - gi|7522549|pir||T38954 probable ubiquitin carboxyl terminal hydrolase - fission yeast (Schizosacchar...
428.0 [0..4] [297..5]
gi|220944844, gi... - gi|220954760|gb|ACL89923.1| l(2)s5379-PA [synthetic construct], gi|220944844|gb|ACL84965.1| l(2)s537...
l(2)s5379-PA, l(... - The gene lethal (2) s5379 is referred to in FlyBase by the symbol Dmel\l(2)s5379 (CG7085, FBgn001070...
423.0 [0..9] [340..1]
GOLPH3 - golgi phosphoprotein 3 (coat-protein)
gi|55624518 - gi|55624518|ref|XP_517830.1| PREDICTED: golgi phosphoprotein 3 isoform 2 [Pan troglodytes]
423.0 [0..1] [340..1]
VPS74_ASHGO, VP7... - Vacuolar protein sorting-associated protein 74 OS=Ashbya gossypii GN=VPS74 PE=3 SV=1, (P62583) Vacuo...
VPS74_ASHGO - Vacuolar protein sorting-associated protein 74 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / ...
413.0 [0..3] [345..2]
GOLP3_MOUSE - Golgi phosphoprotein 3 OS=Mus musculus GN=Golph3 PE=1 SV=1
gi|149027294, gi... - gi|62461580|ref|NP_076467.2| golgi phosphoprotein 3 (coat-protein) [Rattus norvegicus], gi|62205048|...
413.0 [0..1] [340..1]
GOLP3_RAT - Golgi phosphoprotein 3 OS=Rattus norvegicus GN=Golph3 PE=1 SV=1
413.0 [0..1] [340..1]
CE24362 - status:Partially_confirmed UniProt:Q9N3S8 protein_id:AAF60665.1
396.0 [0..20] [340..5]

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Predicted Domain #1
Region A:
Residues: [1-64]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLQRRRVN RADSGDTSSI HSSANNTKGD KIANIAVDGD DDNGTNKKIA YDPEESKLRD  60
   61 NINI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.560 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.549 g.18.1 Complement control module/SCR domain
View Download 0.540 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.537 g.18.1 Complement control module/SCR domain
View Download 0.526 g.81.1 Description not found.
View Download 0.442 g.18.1 Complement control module/SCR domain
View Download 0.436 g.18.1 Complement control module/SCR domain
View Download 0.406 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains

Predicted Domain #2
Region A:
Residues: [65-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTLTLMEEVL LMGLRDREGY LSFWNDSISY ALRGCIIIEL ALRGKIRILD DSARKRFDLS  60
   61 ERLIEVIDSS KTGEVLLDET LQLMKNDEPL SISNWIDLLS GETWNLLKIN YQLKQVRERL 120
  121 AKGLVDKGVL RTEMKNFFLF DMATHPIADA SCKEAIKRRV LSVLVSRNME LSYNEYFPET 180
  181 TSFKIIRTLA LICGSYGANV LENVLTTLEY EKRDKAISRA EEIMAQFSQY PFDLEKETEL 240
  241 GVSVNLNKEV KEEIENNPGH DLQLEVIAGV FEVFSRMDML L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle