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View Structure Prediction Details

Protein: YFT2
Organism: Saccharomyces cerevisiae
Length: 274 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFT2.

Description E-value Query
Range
Subject
Range
YFT2 - Putative protein of unknown function, identified as an ortholog of the highly conserved FIT family o...
YFT2_YEAST - FIT family protein YFT2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YFT2 PE=1 SV=1
5.0E-85 [1..274] [1..274]
CG10671-PA - This gene is referred to in FlyBase by the symbol Dmel\CG10671 (CG10671, FBgn0035586). It is a prote...
3.0E-56 [19..264] [77..319]
FITM1_MOUSE - Fat storage-inducing transmembrane protein 1 OS=Mus musculus GN=Fitm1 PE=1 SV=1
4.0E-42 [10..263] [53..268]
SPBC543.08 - phosphoinositide biosynthesis protein
SCS3_SCHPO - FIT family protein scs3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=scs3 PE=3 SV=1
8.0E-42 [12..261] [26..234]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRQLNYWSR KAYLIYPFQV FVGALLSIVV SSETLNHQKE TCALLKSSNI FNVIFAYKAN  60
   61 QLWPFLFFSL AFLQIYFHYL ARMDILPLPI SSTETSSSYL TYTNHWPLLK NRIISIMITQ 120
  121 YACKFVLKYL LLFLNFQFID HVFIWTGGEC SSGSKTTSAE KCRLENGKWD 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [171-274]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGFDISGHFC FLVSISMILW MELHLFSRFV QAEDMFWVVN KWVRACLAIV CAVLVIWICI  60
   61 LWVTAIYYHT ILEKVLGCLM GFICPVFIYH ILPKIGILHN YLYL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.979 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.973 N/A N/A a.7.7 BAG domain
View Download 0.960 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.957 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.926 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle