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View Structure Prediction Details

Protein: PEX10
Organism: Saccharomyces cerevisiae
Length: 337 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX10.

Description E-value Query
Range
Subject
Range
PEX10_YEAST - Peroxisome biogenesis factor 10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEX10 PE...
PEX10 - Peroxisomal membrane E3 ubiquitin ligase required for for Ubc4p-dependent Pex5p ubiquitination and p...
gi|207346521 - gi|207346521|gb|EDZ72995.1| YDR265Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190404787 - gi|190404787|gb|EDV08054.1| C3HC4 zinc-binding integral peroxisomal membrane protein [Saccharomyces ...
1.0E-81 [1..337] [1..337]
PEX10_ARATH - Peroxisome biogenesis factor 10 OS=Arabidopsis thaliana GN=PEX10 PE=1 SV=1
5.0E-60 [19..336] [25..377]
gi|50547683, gi|... - gi|50547683|ref|XP_501311.1| YALI0C01023p [Yarrowia lipolytica], gi|49647178|emb|CAG81606.1| YALI0C0...
gi|9049374, gi|4... - gi|9049374|dbj|BAA99413.1| PEX10 [Yarrowia lipolytica], gi|49647178|emb|CAG81606.1| YALI0C01023p [Ya...
1.0E-58 [19..336] [43..377]
PEXA_PICAN, PEX1... - (Q00940) Peroxisome assembly protein PER8 (Peroxin-10), Peroxisome biogenesis factor 10 OS=Pichia an...
PEX10_PICAN - Peroxisome biogenesis factor 10 OS=Pichia angusta GN=PEX10 PE=3 SV=1
1.0E-57 [20..336] [5..295]
PEX10 - peroxisomal biogenesis factor 10
5.0E-53 [23..336] [6..323]
PEX10_PICPA - Peroxisome biogenesis factor 10 OS=Komagataella pastoris GN=PEX10 PE=1 SV=1
2.0E-48 [20..319] [23..331]
gi|220953698, gi... - gi|220953698|gb|ACL89392.1| CG7864-PA [synthetic construct], gi|220943852|gb|ACL84469.1| CG7864-PA [...
FBpp0305589, CG7... - This gene is referred to in FlyBase by the symbol Dmel\CG7864 (CG7864, FBgn0035233). It is a protein...
4.0E-47 [23..333] [8..293]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-41 [66..336] [1..306]

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Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNDNKLQKE ALMRLSQLRF PFADAPSIVQ AHQKDEQIQG LLIMKVTELC KLIKSQLFVN  60
   61 SYPKELSIFA KLLYLLFTTG RRGRTLGEEY VDLTYTNRKG T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.888 0.336 peroxisomal membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.718 0.336 peroxisomal membrane a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.884 0.336 peroxisomal membrane a.47.2 t-snare proteins
View Download 0.810 0.336 peroxisomal membrane a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.692 0.336 peroxisomal membrane a.7.6 Ribosomal protein S20
View Download 0.676 0.336 peroxisomal membrane a.46.1 Methionine synthase domain
View Download 0.656 0.336 peroxisomal membrane a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.582 0.336 peroxisomal membrane a.24.17 Group V grass pollen allergen
View Download 0.582 0.336 peroxisomal membrane i.11.1 Computational models partly based on NMR data
View Download 0.570 0.336 peroxisomal membrane a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.487 0.336 peroxisomal membrane a.29.2 Bromodomain
View Download 0.480 0.336 peroxisomal membrane a.133.1 Phospholipase A2, PLA2
View Download 0.473 0.336 peroxisomal membrane d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.473 0.336 peroxisomal membrane a.61.1 Retroviral matrix proteins
View Download 0.467 0.336 peroxisomal membrane a.24.3 Cytochromes
View Download 0.464 0.336 peroxisomal membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.450 0.336 peroxisomal membrane a.24.4 Hemerythrin
View Download 0.439 0.336 peroxisomal membrane a.29.4 RecG, N-terminal domain
View Download 0.436 0.336 peroxisomal membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.431 0.336 peroxisomal membrane a.118.1 ARM repeat
View Download 0.428 0.336 peroxisomal membrane a.26.1 4-helical cytokines
View Download 0.404 0.336 peroxisomal membrane a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.390 0.336 peroxisomal membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.389 0.336 peroxisomal membrane a.90.1 Transcription factor STAT-4 N-domain
View Download 0.379 0.336 peroxisomal membrane a.5.4 Elongation factor TFIIS domain 2
View Download 0.367 0.336 peroxisomal membrane a.118.16 Testis/brain RNA-binding protein (TB-RBP)
View Download 0.366 0.336 peroxisomal membrane a.26.1 4-helical cytokines
View Download 0.366 0.336 peroxisomal membrane a.118.8 TPR-like
View Download 0.360 0.336 peroxisomal membrane a.2.3 Chaperone J-domain
View Download 0.351 0.336 peroxisomal membrane a.7.1 Spectrin repeat
View Download 0.339 0.336 peroxisomal membrane a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.333 0.336 peroxisomal membrane a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.332 0.336 peroxisomal membrane a.26.1 4-helical cytokines
View Download 0.330 0.336 peroxisomal membrane a.16.1 S15/NS1 RNA-binding domain
View Download 0.327 0.336 peroxisomal membrane a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.318 0.336 peroxisomal membrane a.2.7 tRNA-binding arm
View Download 0.309 0.336 peroxisomal membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.294 0.336 peroxisomal membrane a.26.1 4-helical cytokines
View Download 0.291 0.336 peroxisomal membrane d.150.1 4'-phosphopantetheinyl transferase
View Download 0.279 0.336 peroxisomal membrane a.26.1 4-helical cytokines
View Download 0.277 0.336 peroxisomal membrane a.2.3 Chaperone J-domain
View Download 0.277 0.336 peroxisomal membrane a.24.3 Cytochromes
View Download 0.276 0.336 peroxisomal membrane a.112.1 Description not found.
View Download 0.274 0.336 peroxisomal membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.271 0.336 peroxisomal membrane a.26.1 4-helical cytokines
View Download 0.270 0.336 peroxisomal membrane d.95.2 Homing endonucleases
View Download 0.255 0.336 peroxisomal membrane a.74.1 Cyclin-like
View Download 0.255 0.336 peroxisomal membrane a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.254 0.336 peroxisomal membrane a.24.12 Outer surface protein C (OspC)
View Download 0.252 0.336 peroxisomal membrane f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.251 0.336 peroxisomal membrane a.71.2 Helical domain of Sec23/24
View Download 0.251 0.336 peroxisomal membrane a.74.1 Cyclin-like
View Download 0.248 0.336 peroxisomal membrane a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.246 0.336 peroxisomal membrane a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.241 0.336 peroxisomal membrane f.17.1 F1F0 ATP synthase subunit C
View Download 0.240 0.336 peroxisomal membrane a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.239 0.336 peroxisomal membrane a.26.1 4-helical cytokines
View Download 0.238 0.336 peroxisomal membrane a.7.1 Spectrin repeat
View Download 0.235 0.336 peroxisomal membrane a.29.2 Bromodomain
View Download 0.232 0.336 peroxisomal membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.231 0.336 peroxisomal membrane a.17.1 p8-MTCP1
View Download 0.228 0.336 peroxisomal membrane i.1.1 Ribosome and ribosomal fragments
View Download 0.225 0.336 peroxisomal membrane a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.222 0.336 peroxisomal membrane a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.221 0.336 peroxisomal membrane a.24.17 Group V grass pollen allergen
View Download 0.221 0.336 peroxisomal membrane a.16.1 S15/NS1 RNA-binding domain
View Download 0.220 0.336 peroxisomal membrane a.71.2 Helical domain of Sec23/24
View Download 0.218 0.336 peroxisomal membrane a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.214 0.336 peroxisomal membrane a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.212 0.336 peroxisomal membrane a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.205 0.336 peroxisomal membrane a.7.5 Tubulin chaperone cofactor A
View Download 0.201 0.336 peroxisomal membrane f.1.4 Bcl-2 inhibitors of programmed cell death

Predicted functions:

Term Confidence Notes
nucleic acid binding 1.94188352248723 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [102-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLAGRLKMIV FAFAYPLCPY FITKLYKKIM KNNKESKIED TESVAAFCKG LLDFILDVHM  60
   61 TLFYFKGAFY SISKRIFGMR YVFKHILSKN EANFREEGSQ KYKVLGYILL AQNVMKWYPV 120
  121 LTSTLGSWIY GRKRTNDSIT RSSVGLQERS EHESIEGIPK ESQLTHINLS DKNQLPFIPE 180
  181 ASRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.24799
Match: 1fbvA_
Description: Cbl; N-terminal domain of cbl (N-cbl); CBL
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [286-337]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CILCLMNMSD PSCAPCGHLF CWSCLMSWCK ERPECPLCRQ HCQPQEILVL RQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.24799
Match: 1fbvA_
Description: Cbl; N-terminal domain of cbl (N-cbl); CBL
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle