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View Structure Prediction Details

Protein: AKR1
Organism: Saccharomyces cerevisiae
Length: 764 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AKR1.

Description E-value Query
Range
Subject
Range
gi|207346520 - gi|207346520|gb|EDZ72994.1| YDR264Cp-like protein [Saccharomyces cerevisiae AWRI1631]
AKR1_YEAST - Palmitoyltransferase AKR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AKR1 PE=1 SV=1
AKR1 - Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone ...
0.0 [1..764] [1..764]
gi|4589536 - gi|4589536|dbj|BAA76790.1| KIAA0946 protein [Homo sapiens]
0.0 [80..643] [99..645]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [6..466] [239..681]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [6..466] [239..681]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVNELENVPR ASTLTNEEQT VDPSNNDSQE DISLGDSNEI TSLASLKAIR SGNEEESGNE  60
   61 QVNHNDEAEE DPLLTRYHTA CQRGDLATVK EMIHGKLLEV NNDGDSTEHI TGLHWASINN 120
  121 RLSVVDFLVS QGADVNARAG ALHATPLHWA ARYGYVYIVD FLLKHGADPT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.917458
Match: 1k1aA_
Description: bcl-3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 2.69918165732603 bayes_pls_golite062009
hydrolase activity 2.43232200709693 bayes_pls_golite062009
binding 2.17983095277661 bayes_pls_golite062009
cytoskeletal protein binding 1.93050618316228 bayes_pls_golite062009
structural constituent of cytoskeleton 1.29094941611102 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.23556500721571 bayes_pls_golite062009
transporter activity 1.19000052859754 bayes_pls_golite062009
transmembrane transporter activity 1.02570255606772 bayes_pls_golite062009
structural molecule activity 0.808967137205604 bayes_pls_golite062009
receptor activity 0.794712986057462 bayes_pls_golite062009
molecular transducer activity 0.789486768149117 bayes_pls_golite062009
signal transducer activity 0.789486768149117 bayes_pls_golite062009
transmembrane receptor activity 0.694785132815586 bayes_pls_golite062009
enzyme binding 0.60140077251711 bayes_pls_golite062009
substrate-specific transporter activity 0.581121752453591 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.428839878681413 bayes_pls_golite062009
transcription regulator activity 0.304692936026767 bayes_pls_golite062009
acid-amino acid ligase activity 0.247967126091535 bayes_pls_golite062009
ion transmembrane transporter activity 0.240863793118641 bayes_pls_golite062009
nucleic acid binding 0.171334135216535 bayes_pls_golite062009
actin binding 0.168912685840912 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [171-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDDQGFNLL HLSVNSSNIM LVLYVLFNVV SKGLLDIDCR DPKGRTSLLW AAYQGDSLTV  60
   61 AELLKFGASI KIADTEGFTP LHWGTVKGQP HVLKYLIQDG ADFFQKTDTG KDCFAIAQEM 120
  121 NTVYSLREAL THSGFDYHGY PIKKWFKKSQ HAKLVTFITP FLFLGIAFAL FSHI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 111.917458
Match: 1k1aA_
Description: bcl-3
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [345-653]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPLFVIIVLF LLAIATNKGL NKFVLPSYGR MGVHNVTLLR SPLLSGVFFG TLLWVTIVWF  60
   61 FKVMPRTFSD EQYTNILMLV ILVSVFYLFG QLVIMDPGCL PEETDHENVR QTISNLLEIG 120
  121 KFDTKNFCIE TWIRKPLRSK FSPLNNAVVA RFDHYCPWIF NDVGLKNHKA FIFFITLMES 180
  181 GIFTFLALCL EYFDELEDAH EDTSQKNGKC FILGASDLCS GLIYDRFVFL ILLWALLQSI 240
  241 WVASLIFVQA FQICKGMTNT EFNVLMKESK SIGPDGLSFN ENFNTTPEGF APSIDPGEES 300
  301 NDTVLAPVP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [654-764]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSTIRKPRTC FGVCYAVTGM DQWLAVIKET IGIKDSTGHN VYSITSRIPT NYGWKRNVKD  60
   61 FWLTSDINAP LWRRILYPPS GSKALLNGIE VDYFKLYKLP NKDVEQGNDM V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle