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View Structure Prediction Details

Protein: YAP6
Organism: Saccharomyces cerevisiae
Length: 383 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YAP6.

Description E-value Query
Range
Subject
Range
MYH6 - myosin, heavy chain 6, cardiac muscle, alpha
1.0E-43 [12..378] [1490..1852]
MYH7_PIG - Myosin-7 OS=Sus scrofa GN=MYH7 PE=2 SV=2
1.0E-43 [12..378] [1488..1850]
MYH7_MESAU - Myosin-7 OS=Mesocricetus auratus GN=MYH7 PE=2 SV=2
2.0E-43 [12..378] [1487..1849]
MYH7_BOVIN - Myosin-7 OS=Bos taurus GN=MYH7 PE=1 SV=1
2.0E-43 [12..378] [1488..1850]
MYH7_MOUSE - Myosin-7 OS=Mus musculus GN=Myh7 PE=1 SV=1
2.0E-43 [12..378] [1488..1850]

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Predicted Domain #1
Region A:
Residues: [1-57]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNPPLIRPD MYNQGSSSMA TYNASEKNLN EHPSPQIAQP STSQKLPYRI NPTTTNG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.458 a.4.5 "Winged helix" DNA-binding domain
View Download 0.316 a.4.1 Homeodomain-like
View Download 0.397 a.64.1 Saposin
View Download 0.335 a.144.2 Ribosomal protein L20
View Download 0.311 a.65.1 Annexin
View Download 0.301 a.4.5 "Winged helix" DNA-binding domain
View Download 0.282 a.60.2 RuvA domain 2-like
View Download 0.246 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.223 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.200 a.37.1 A DNA-binding domain in eukaryotic transcription factors

Predicted Domain #2
Region A:
Residues: [58-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTDISVNSNP IQPPLPNLMH LSGPSDYRSM HQSPIHPSYI IPPHSNERKQ SASYNRPQNA  60
   61 HVSIQPSVVF PPKSYSISYA PYQINPPLPN GLPNQSISLN KEYIAEEQLS TLPSRNTSVT 120
  121 TAPPSFQNSA DTAKNSADNN DNNDNVTKPV PDKDTQLISS SGKTLRNTRR AAQNRTAQKA 180
  181 FRQRKEKYIK NLEQKSKIFD DLLAENNNFK SLNDSLRNDN NILIAQHEAI RNAITMLRSE 240
  241 YDVLCNENNM LKNENSIIKN EHNMSRNENE NLKLENKRFH AEYIRMIEDI ENTKRKEQEQ 300
  301 RDEIEQLKKK IRSLEEIVGR HSDSAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.045757
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle