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View Structure Prediction Details

Protein: RMD5
Organism: Saccharomyces cerevisiae
Length: 421 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RMD5.

Description E-value Query
Range
Subject
Range
gi|151942231 - gi|151942231|gb|EDN60587.1| protein required for maturation and assembly of cytochrome oxidase subun...
RMD5_YEAST - Sporulation protein RMD5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RMD5 PE=1 SV=1
gi|190404797 - gi|190404797|gb|EDV08064.1| sporulation protein RMD5 [Saccharomyces cerevisiae RM11-1a]
RMD5 - Conserved protein that has an E3-like ubiquitin ligase activity necessary for polyubiquitination and...
gi|207346542 - gi|207346542|gb|EDZ73014.1| YDR255Cp-like protein [Saccharomyces cerevisiae AWRI1631]
0.0 [1..421] [1..421]
gi|8099667, gi|1... - gi|8099667|gb|AAF72195.1|AF263247_1 erythroblast macrophage protein EMP [Mus musculus], gi|10946910|...
0.0 [8..417] [15..383]
gi|7022137 - gi|7022137|dbj|BAA91499.1| unnamed protein product [Homo sapiens]
0.0 [8..417] [26..394]
gi|66865920, gi|... - gi|79322754|ref|NP_001031397.1| protein binding / zinc ion binding [Arabidopsis thaliana], gi|668659...
2.0E-93 [53..418] [4..381]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELLDSFET EFAKFYTDSN LEETNLQKCL DHTHEFKSQL KKLKAHLNKH IQESKPEVYN  60
   61 KLSDKEKQKF KR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.665 0.696 cytosol a.4.5 "Winged helix" DNA-binding domain
View Download 0.686 0.000 cytosol a.23.5 Hemolysin expression modulating protein HHA
View Download 0.597 0.000 cytosol a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.686 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.665 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.621 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.608 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.597 N/A N/A a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.597 N/A N/A a.65.1 Annexin
View Download 0.551 N/A N/A a.65.1 Annexin
View Download 0.547 N/A N/A a.17.1 p8-MTCP1
View Download 0.511 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.511 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.511 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.500 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.496 N/A N/A a.77.1 DEATH domain
View Download 0.494 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.463 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.457 N/A N/A a.17.1 p8-MTCP1
View Download 0.457 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.449 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.449 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.448 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.439 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.438 N/A N/A a.64.1 Saposin
View Download 0.436 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.434 N/A N/A a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.424 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.404 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.403 N/A N/A a.64.1 Saposin
View Download 0.399 N/A N/A a.65.1 Annexin
View Download 0.392 N/A N/A a.4.1 Homeodomain-like
View Download 0.388 N/A N/A d.45.1 ClpS-like
View Download 0.385 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.382 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.376 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.368 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.367 N/A N/A a.5.2 UBA-like
View Download 0.365 N/A N/A a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.350 N/A N/A a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.348 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.341 N/A N/A d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.336 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.334 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.332 N/A N/A a.39.1 EF-hand
View Download 0.329 N/A N/A d.50.3 PI-Pfui intein middle domain
View Download 0.329 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.323 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.322 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.320 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.316 N/A N/A f.1.5 Exotoxin A, middle domain
View Download 0.314 N/A N/A a.49.1 C-terminal domain of B transposition protein
View Download 0.314 N/A N/A a.65.1 Annexin
View Download 0.313 N/A N/A a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.304 N/A N/A a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.302 N/A N/A a.64.1 Saposin
View Download 0.300 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.299 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.297 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.296 N/A N/A a.17.1 p8-MTCP1
View Download 0.293 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.291 N/A N/A a.144.2 Ribosomal protein L20
View Download 0.290 N/A N/A a.77.1 DEATH domain
View Download 0.288 N/A N/A a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.288 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.284 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.283 N/A N/A a.23.5 Hemolysin expression modulating protein HHA
View Download 0.281 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.280 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.277 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.276 N/A N/A a.17.1 p8-MTCP1
View Download 0.272 N/A N/A a.1.1 Globin-like
View Download 0.272 N/A N/A a.1.1 Globin-like
View Download 0.270 N/A N/A a.4.1 Homeodomain-like
View Download 0.265 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.263 N/A N/A a.64.1 Saposin
View Download 0.262 N/A N/A a.4.1 Homeodomain-like
View Download 0.262 N/A N/A a.16.1 S15/NS1 RNA-binding domain
View Download 0.261 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.259 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.259 N/A N/A a.157.1 Skp1 dimerisation domain-like
View Download 0.258 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.257 N/A N/A b.84.2 Rudiment single hybrid motif
View Download 0.255 N/A N/A a.46.1 Methionine synthase domain
View Download 0.255 N/A N/A a.4.8 Ribosomal protein S18
View Download 0.253 N/A N/A a.46.1 Methionine synthase domain
View Download 0.250 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.249 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.246 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.244 N/A N/A a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.242 N/A N/A a.161.1 beta-catenin-interacting protein ICAT
View Download 0.242 N/A N/A a.118.1 ARM repeat
View Download 0.241 N/A N/A a.134.1 Fungal elicitin
View Download 0.241 N/A N/A a.59.1 PAH2 domain
View Download 0.240 N/A N/A c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.238 N/A N/A a.1.1 Globin-like
View Download 0.238 N/A N/A a.4.1 Homeodomain-like
View Download 0.237 N/A N/A a.77.1 DEATH domain
View Download 0.236 N/A N/A c.9.1 Barstar (barnase inhibitor)
View Download 0.236 N/A N/A a.5.2 UBA-like
View Download 0.234 N/A N/A a.134.1 Fungal elicitin
View Download 0.233 N/A N/A a.4.1 Homeodomain-like
View Download 0.233 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.229 N/A N/A a.5.3 N-terminal domain of phosphatidylinositol transfer protein sec14p
View Download 0.228 N/A N/A a.36.1 Signal peptide-binding domain
View Download 0.226 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.226 N/A N/A a.1.1 Globin-like
View Download 0.225 N/A N/A a.150.1 Anti-sigma factor AsiA
View Download 0.225 N/A N/A a.39.1 EF-hand
View Download 0.224 N/A N/A a.77.1 DEATH domain
View Download 0.224 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.223 N/A N/A d.50.3 PI-Pfui intein middle domain
View Download 0.220 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.220 N/A N/A a.118.1 ARM repeat
View Download 0.219 N/A N/A a.134.1 Fungal elicitin
View Download 0.218 N/A N/A a.17.1 p8-MTCP1
View Download 0.218 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.215 N/A N/A a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.214 N/A N/A a.1.1 Globin-like
View Download 0.212 N/A N/A a.29.2 Bromodomain
View Download 0.211 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.208 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.208 N/A N/A a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.207 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.207 N/A N/A a.49.1 C-terminal domain of B transposition protein
View Download 0.205 N/A N/A a.134.1 Fungal elicitin
View Download 0.204 N/A N/A a.2.3 Chaperone J-domain

Predicted Domain #2
Region A:
Residues: [73-280]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRELIIEKLS KSQRQWDHSV KKQIKYVSQQ SNRFNKSTLN KLKEFDIDSV YVNKLPKETM  60
   61 ENVNEAIGYH ILRYSIDNMP LGNKNEAFQY LKDVYGITNK ESTEFIEMGQ IVHDLKKGDT 120
  121 ESCLKWCSNE MESLSSNHTA LSSLKFDLYT LSAMQIVKHG NPVELYYQIT QNAPLDCFRH 180
  181 REKELMQNVV PLLTKSLIGQ PIEDIDSK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [281-421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNKELKECTS LFIKEYCAAK HIFFDSPLFL IVLSGLISFQ FFIKYKTIRE LAHVDWTTKD  60
   61 ELPFDVKLPD FLTHFHPIFI CPVLKEETTT ENPPYSLACH HIISKKALDR LSKNGTITFK 120
  121 CPYCPVNTSM SSTKKVRFVM L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.281 0.930 cytosol a.1.1 Globin-like
View Download 0.269 0.045 cytosol d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.296 0.000 cytosol a.74.1 Cyclin-like
View Download 0.273 0.000 cytosol a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.275 0.000 cytosol a.167.1 Porin chaperone SurA, peptide-binding domain
View Download 0.232 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.228 N/A N/A a.24.1 Apolipoprotein
View Download 0.221 N/A N/A a.182.1 GatB/YqeY domain
View Download 0.200 N/A N/A c.55.1 Actin-like ATPase domain

Predicted Domain #4
Region A:
Residues: [316-421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LISFQFFIKY KTIRELAHVD WTTKDELPFD VKLPDFLTHF HPIFICPVLK EETTTENPPY  60
   61 SLACHHIISK KALDRLSKNG TITFKCPYCP VNTSMSSTKK VRFVML

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 2ct2A
Description: Solution Structure of the RING domain of the Tripartite motif protein 32
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle