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View Structure Prediction Details

Protein: PRP28
Organism: Saccharomyces cerevisiae
Length: 588 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRP28.

Description E-value Query
Range
Subject
Range
gi|13514813, gi|... - gi|2580552|gb|AAC51830.1| dead box, X isoform [Homo sapiens], gi|2580550|gb|AAC51829.1| dead box, X ...
0.0 [5..576] [10..579]
DDX3X_MOUSE - ATP-dependent RNA helicase DDX3X OS=Mus musculus GN=Ddx3x PE=1 SV=3
0.0 [5..576] [10..579]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [5..576] [10..579]
DDX3_XENLA - Putative ATP-dependent RNA helicase an3 OS=Xenopus laevis GN=an3 PE=2 SV=1
0.0 [5..576] [10..620]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [5..576] [10..620]
gi|10039327 - gi|10039327|dbj|BAB13306.1| PL10-related protein CnPL10 [Hydra magnipapillata]
0.0 [6..583] [11..579]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARPIDVSQL IAGINKKKGL DENTSGKISK PRFLNKQERS KQERLKENEE SLTPTQSDSA  60
   61 KVEIKKVNSR DDSFFNETND KKRNPSKQNG SKFHFSWNES EDTLSGYDPI VSTRAIDLLW 120
  121 KGKTPKNAAE SSYMGKHWT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [140-402]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKSLHEMNER DWRILKEDYA IVTKGGTVEN PLRNWEELNI IPRDLLRVII QELRFPSPTP  60
   61 IQRITIPNVC NMKQYRDFLG VASTGSGKTL AFVIPILIKM SRSPPRPPSL KIIDGPKALI 120
  121 LAPTRELVQQ IQKETQKVTK IWSKESNYDC KVISIVGGHS LEEISFSLSE GCDILVATPG 180
  181 RLIDSLENHL LVMKQVETLV LDEADKMIDL GFEDQVTNIL TKVDINADSA VNRQTLMFTA 240
  241 TMTPVIEKIA AGYMQKPVYA TIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 503.0
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [403-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VETGSEPLIQ QVVEYADNDE DKFKKLKPIV AKYDPPIIIF INYKQTADWL AEKFQKETNM  60
   61 KVTILHGSKS QEQREHSLQL FRTNKVQIMI ATNVAARGLD IPNVSLVVNF QISKKMDDYI 120
  121 HRIGRTGRAA NEGTAVSFVS AAEDESLIRE LYKYVRKHDP LNSNIFSEAV KNKYNVGKQL 180
  181 SNEIIY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 503.0
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle