YRC Public Data Repository - Protein Structure Prediction

Protein:	FMN1
Organism:	Saccharomyces cerevisiae
Length:	218 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FMN1.

Description	E-value	Query Range	Subject Range
gi\|190404814 - gi\|190404814\|gb\|EDV08081.1\| riboflavin kinase [Saccharomyces cerevisiae RM11-1a] RIFK_YEAST - Riboflavin kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FMN1 PE=1 SV=1 FMN1 - Riboflavin kinase, phosphorylates riboflavin to form riboflavin monophosphate (FMN), which is a nece... gi\|207346551 - gi\|207346551\|gb\|EDZ73020.1\| YDR236Cp-like protein [Saccharomyces cerevisiae AWRI1631]	8.0E-63	[1..218]	[1..218]
gi\|19553182, gi\|... - gi\|62390818\|ref\|YP_226220.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Corynebacterium... gi\|145295882, gi... - gi\|145295882\|ref\|YP_001138703.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Corynebacte...	4.0E-45	[2..208]	[146..328]
RIBF_CORAM - Riboflavin biosynthesis protein RibF OS=Corynebacterium ammoniagenes GN=ribF PE=1 SV=1	1.0E-42	[5..207]	[148..319]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-41	[4..208]	[143..306]
RIBF_SYNY3 - Riboflavin biosynthesis protein RibF OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=ribF PE=3 SV... gi\|7444635 - pir\|\|S77138 hypothetical protein slr1882 - Synechocystis sp. (strain PCC 6803) RIBF_SYNY3 - Riboflavin biosynthesis protein ribF OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=ri...	2.0E-40	[2..208]	[115..279]
gi\|17133985, gi\|... - gi\|17232340\|ref\|NP_488888.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Nostoc sp. PCC ... gi\|25302156 - pir\|\|AH2411 riboflavin kinase/FAD synthase [imported] - Nostoc sp. (strain PCC 7120)	3.0E-40	[6..209]	[178..361]
RIFK_MOUSE - Riboflavin kinase OS=Mus musculus GN=Rfk PE=1 SV=2	4.0E-40	[51..217]	[6..141]
gi\|15603526, gi\|... - gi\|15603526\|ref\|NP_246600.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Pasteurella mul...	7.0E-40	[23..208]	[162..308]
gi\|16768454 - gi\|16768454\|gb\|AAL28446.1\| GM04958p [Drosophila melanogaster]	7.0E-40	[52..216]	[8..141]
gi\|15827378 - gi\|15827378\|ref\|NP_301641.1\| bifunctional riboflavin kinase/FMN adenylyltransferase [Mycobacterium l... gi\|13092928, gi\|... - gi\|2342621\|emb\|CAB11394.1\| riboflavin kinase [Mycobacterium leprae], gi\|13092928\|emb\|CAC31233.1\| put... gi\|219932962, gi... - gi\|221229855\|ref\|YP_002503271.1\| putative riboflavin kinase [Mycobacterium leprae Br4923], gi\|219932...	1.0E-38	[25..207]	[176..330]

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Predicted Domain #1

Region A:
Residues: [1-69]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTWTIYVSL LLVLAGTFLM NRNTNTDIID TFKREVDLPI PAQPGPPFPL VTDYCDIVCG  60
   61 FGRGSAELG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
riboflavin kinase activity	9.29267848240079	bayes_pls_golite062009
FMN adenylyltransferase activity	7.46254172012226	bayes_pls_golite062009
kinase activity	2.06841232315201	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.04516341526682	bayes_pls_golite062009
adenylyltransferase activity	2.0444249049462	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.03375669869689	bayes_pls_golite062009
catalytic activity	2.03120709726017	bayes_pls_golite062009
transferase activity	1.98609814060536	bayes_pls_golite062009
nucleotidyltransferase activity	1.19728391053646	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [70-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPTANVPINQ LPKGINDLDL GVYFGFAHIK TVDGQELSVE TRRDGRTVVY NYGQYLSEAN  60
   61 DDLSVLPMVL SVGKNPFYGN DFKTMELHII HDFKNDFYGA RVKFNILGHI RPELNYTTKE 120
  121 ALIEDINIDI RTAQTVLATP PYQVFKQQL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	50.30103
Match:	PF01687
Description:	Riboflavin kinase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: