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View Structure Prediction Details

Protein: RTN1
Organism: Saccharomyces cerevisiae
Length: 295 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RTN1.

Description E-value Query
Range
Subject
Range
RTN1 - ER membrane protein that interacts with Sey1p to maintain ER morphology; interacts with exocyst subu...
RTN1_YEAST - Reticulon-like protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RTN1 PE=1 SV=1
2.0E-82 [1..295] [1..295]
RTNLB_ARATH - Reticulon-like protein B2 OS=Arabidopsis thaliana GN=RTNLB2 PE=1 SV=1
2.0E-65 [5..207] [70..270]
gi|125569591, gi... - gi|34904202|ref|NP_913448.1| P0492F05.25 [Oryza sativa (japonica cultivar-group)], gi|20804416|dbj|B...
3.0E-61 [5..206] [79..278]
RTN2_MOUSE - Reticulon-2 OS=Mus musculus GN=Rtn2 PE=1 SV=1
5.0E-50 [19..230] [271..471]

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Predicted Domain #1
Region A:
Residues: [1-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASAQHSQA QQQQQQKSCN CDLLLWRNPV QTGKYFGGSL LALLILKKVN LITFFLKVAY  60
   61 TILFTTGSIE FVSKLFLGQG LITKYGPKEC PNIAGFIKPH IDEALKQLPV FQAHIRKTVF 120
  121 AQVPKHTFKT AVALFLLHKF FSWFSIWTIV FVADIFTFTL PVIYHSYKHE IDATVAQGVE 180
  181 ISKQKTQEFS QMACEKTKPY LDKVESKLGP ISNLVKSKT

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 78.283997
Match: PF02453
Description: Reticulon

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [220-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APVSSTAGPQ TASTSKLAAD VPLEPESKAY TSSAQVMPEV PQHEPSTTQE FNVDELSNEL  60
   61 KKSTKNLQNE LEKNNA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.527 a.4.5 "Winged helix" DNA-binding domain
View Download 0.376 a.4.1 Homeodomain-like
View Download 0.506 a.144.1 PABC (PABP) domain
View Download 0.360 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.355 a.46.1 Methionine synthase domain
View Download 0.344 a.64.1 Saposin
View Download 0.343 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.313 a.4.1 Homeodomain-like
View Download 0.299 a.7.6 Ribosomal protein S20
View Download 0.281 a.60.8 HRDC-like
View Download 0.257 a.4.5 "Winged helix" DNA-binding domain
View Download 0.242 a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.203 a.76.1 Iron-dependent represor protein, dimerization domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle