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View Structure Prediction Details

Protein: YDR124W
Organism: Saccharomyces cerevisiae
Length: 324 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YDR124W.

Description E-value Query
Range
Subject
Range
YD124_YEAST - Uncharacterized protein YDR124W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDR124W ...
YDR124W - Putative protein of unknown function; non-essential gene; expression is strongly induced by alpha fa...
0.0 [1..324] [1..324]
gi|11596254 - gi|11596254|gb|AAG38543.1|AF309805_8 Ydr124wp-like protein [Pneumocystis carinii f. sp. carinii]
3.0E-34 [92..162] [78..148]

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Predicted Domain #1
Region A:
Residues: [1-63]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIGMEELRR ALALLNGQGY EFMVFIKEKD HLISESIPKN LFSESFISSS IEKNPPLTFD  60
   61 PLV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.964 d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.964 d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.911 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.911 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.889 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.861 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.822 d.58.3 Protease propeptides/inhibitors
View Download 0.822 d.58.3 Protease propeptides/inhibitors
View Download 0.629 d.58.10 Acylphosphatase-like
View Download 0.562 d.58.49 YajQ-like
View Download 0.542 d.58.17 Metal-binding domain
View Download 0.533 d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.521 d.58.7 RNA-binding domain, RBD
View Download 0.436 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.427 d.58.5 GlnB-like
View Download 0.426 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.421 d.68.3 SirA-like
View Download 0.404 d.58.24 CheY-binding domain of CheA
View Download 0.388 a.64.2 Bacteriocin AS-48
View Download 0.380 a.4.5 "Winged helix" DNA-binding domain
View Download 0.362 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.353 d.58.40 D-ribose-5-phosphate isomerase (RpiA), lid domain
View Download 0.349 a.4.1 Homeodomain-like
View Download 0.335 c.5.1 MurCD N-terminal domain
View Download 0.332 a.7.6 Ribosomal protein S20
View Download 0.327 c.23.1 CheY-like
View Download 0.324 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.322 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.321 a.4.5 "Winged helix" DNA-binding domain
View Download 0.320 c.5.1 MurCD N-terminal domain
View Download 0.302 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.297 d.50.3 PI-Pfui intein middle domain
View Download 0.292 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.279 d.58.38 Urease metallochaperone UreE, C-terminal domain
View Download 0.275 a.4.1 Homeodomain-like
View Download 0.264 d.58.36 Sulfite reductase, domains 1 and 3
View Download 0.264 a.6.1 Putative DNA-binding domain
View Download 0.263 d.58.7 RNA-binding domain, RBD
View Download 0.248 a.65.1 Annexin
View Download 0.245 d.74.5 Hypothetical protein Yml108w
View Download 0.239 d.68.7 R3H domain
View Download 0.232 d.64.1 eIF1-like
View Download 0.230 b.1.18 E set domains
View Download 0.220 d.58.8 Viral DNA-binding domain
View Download 0.214 a.4.1 Homeodomain-like
View Download 0.212 a.144.2 Ribosomal protein L20
View Download 0.207 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.203 a.64.1 Saposin
View Download 0.202 d.58.3 Protease propeptides/inhibitors

Predicted Domain #2
Region A:
Residues: [64-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRKRITVYEE NIQPAIMLPL DQPLLIQNYL YTAFKLLRQV PCKAIAKLWI KIIEPRKKTR  60
   61 FPYIKGNAGR PEWWPKDVEH KEPDHLQKAD RLKLMCTIIM NV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.642 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.529 N/A N/A a.1.1 Globin-like
View Download 0.479 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.436 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.371 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.366 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.358 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.333 N/A N/A a.118.8 TPR-like
View Download 0.315 N/A N/A d.141.1 Ribosomal protein L6
View Download 0.313 N/A N/A d.42.1 POZ domain
View Download 0.294 N/A N/A c.98.2 HPr kinase/phoshatase HprK N-terminal domain
View Download 0.293 N/A N/A d.15.1 Ubiquitin-like
View Download 0.275 N/A N/A d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.262 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.253 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.252 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.245 N/A N/A a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.232 N/A N/A a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.227 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.227 N/A N/A a.1.1 Globin-like
View Download 0.223 N/A N/A a.7.7 BAG domain
View Download 0.215 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.214 N/A N/A c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.204 N/A N/A c.55.4 Translational machinery components
View Download 0.203 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin

Predicted Domain #3
Region A:
Residues: [166-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPQSPFSLEI LDELTGVTAA MTIFKKETVK KVIMKNVFEI AKCLCNKDFK QKTISLDDLN  60
   61 DLAQKQKKSY HSRRFDVNKM VKVEKDLLQQ SSGSDSSPSM ILPSKESDTE YFPREYPKDP 120
  121 VSEDYSNSIS RLENLVEFDP LFLTKLDELT SSDDCKDFI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle