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View Structure Prediction Details

Protein: ALT2
Organism: Saccharomyces cerevisiae
Length: 507 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALT2.

Description E-value Query
Range
Subject
Range
gi|7576444 - gi|7576444|dbj|BAA94600.1| 1-aminocyclopropane-1-carboxylate synthase [Populus euramericana]
gi|7576444 - dbj|BAA94600.1| 1-aminocyclopropane-1-carboxylate synthase [Populus euramericana]
0.0 [56..506] [25..433]
gi|8570043 - gi|8570043|dbj|BAA96743.1| 1-aminocyclopropane-1-carboxylate synthase [Prunus persica]
0.0 [56..506] [30..437]
1A11_PRUMU - 1-aminocyclopropane-1-carboxylate synthase 1 OS=Prunus mume GN=ACS1 PE=2 SV=1
0.0 [56..506] [30..437]
1A1C_TOBAC - 1-aminocyclopropane-1-carboxylate synthase OS=Nicotiana tabacum GN=ACS1 PE=2 SV=1
0.0 [56..507] [29..439]
gi|3955254 - gi|3955254|gb|AAC83147.1| 1-aminocyclopropane-1-carboxylate synthase [Nicotiana glutinosa]
0.0 [56..506] [31..439]
gi|3643540 - gi|3643540|emb|CAA09477.1| ACC synthase [Citrus sinensis]
0.0 [56..506] [21..428]
gi|4090535 - gi|4090535|gb|AAC98809.1| ACC synthase [Carica papaya]
0.0 [56..506] [28..437]
gi|7209853 - gi|7209853|dbj|BAA92351.1| 1-aminocyclopropane-1-carboxylate synthase [Malus x domestica]
0.0 [56..506] [29..437]
1A1C_SOYBN - 1-aminocyclopropane-1-carboxylate synthase OS=Glycine max GN=ACS1 PE=2 SV=1
0.0 [56..506] [29..439]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMTHQQDLK GVFTAKDLDF KPAGKITKKD LNTGVTKAEY AVRGAIPTRA DELKEELKKN  60
   61 PEVLPFDDII NANIGNPQQL D

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [402-507]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RANLLYETFK ELEGIECQKP QGAMYLFPRL VLPKKALCES ERLGIEPDEF YCTSLLESTG  60
   61 ICTVPGSGFG QRPGTYHVRT TFLAPGTKWI QDWKEFHQDF FSKYRN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 321.9691
Match: 1iaxA_
Description: 1-aminocyclopropane-1-carboxylate synthase (ACC synthase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
L-aspartate:2-oxoglutarate aminotransferase activity 5.51961002550688 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
4-aminobutyrate transaminase activity 1.82501790383768 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 1.63055151623667 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 1.63055151623667 bayes_pls_golite062009
transferase activity 1.44093490824786 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
L-alanine:2-oxoglutarate aminotransferase activity 1.06988190956423 bayes_pls_golite062009
alanine-oxo-acid transaminase activity 1.06988190956423 bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances 0.942545094747784 bayes_pls_golite062009
hydrolase activity, acting on acid carbon-carbon bonds 0.845816961387768 bayes_pls_golite062009
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity 0.753443687983955 bayes_pls_golite062009
binding 0.536634592992536 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.319452731970428 bayes_pls_golite062009
pyridoxal phosphate binding 0.16957228630576 bayes_pls_golite062009
vitamin B6 binding 0.16957228630576 bayes_pls_golite062009
aromatic-amino-acid:2-oxoglutarate aminotransferase activity 0.0916183433120769 bayes_pls_golite062009
kynureninase activity 0.0900983660305177 bayes_pls_golite062009
cystathionine beta-lyase activity 0.0833010353195099 bayes_pls_golite062009
nucleic acid binding 0.013097682076602 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [82-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKPLTFTRQV LAILEYPEIL RVGHNELASL NLFSRDALER AERLLNDIGG SIGAYSHSQG  60
   61 VPGIRQTVAD FITRRDGGEP ATPEDIYLTT GASSAATSLL SLLCKDSQTG LLIPIPQYPL 120
  121 YTASASLFNA QVLPYYLDEE SNWSTNSDEI EKVVQDALKK QIRPSVLIVI NPGNPTGAVL 180
  181 SEETIARICL IAAKYGITII SDEVYQENIF NDVKFHSMKK VLRKLQHLYP GKFDNVQLAS 240
  241 LHSISKGFMD ECGQRGGYME IIGFSQEIRD ALFKLMSISI CSVVTGQAVV DLMVKPPQPG 300
  301 DESYEQDHDE RLKIFHEMRT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 321.9691
Match: 1iaxA_
Description: 1-aminocyclopropane-1-carboxylate synthase (ACC synthase)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle