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View Structure Prediction Details

Protein: KCS1
Organism: Saccharomyces cerevisiae
Length: 1050 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KCS1.

Description E-value Query
Range
Subject
Range
gi|151942005 - gi|151942005|gb|EDN60361.1| inositol polyphosphate kinase [Saccharomyces cerevisiae YJM789]
KCS1 - Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of high ener...
KCS1_YEAST - Inositol hexakisphosphate kinase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KCS1 ...
0.0 [1..1050] [1..1050]
SPCC970.08 - inositol polyphosphate kinase
YCZ8_SCHPO - Uncharacterized inositol polyphosphate kinase C970.08 OS=Schizosaccharomyces pombe (strain 972 / ATC...
0.0 [105..963] [35..927]
gi|18376053, gi|... - gi|32404382|ref|XP_322804.1| hypothetical protein [Neurospora crassa], gi|28917903|gb|EAA27589.1| pr...
gi|85081967 - gi|85081967|ref|XP_956825.1| hypothetical protein NCU03546 [Neurospora crassa OR74A]
0.0 [119..980] [547..1450]
gi|19527563 - gi|19527563|gb|AAL89896.1| RE35745p [Drosophila melanogaster]
0.0 [501..964] [139..635]
IP6K2_RABIT - Inositol hexakisphosphate kinase 2 OS=Oryctolagus cuniculus GN=IP6K2 PE=2 SV=1
0.0 [612..969] [54..424]
IP6K1_RAT - Inositol hexakisphosphate kinase 1 OS=Rattus norvegicus GN=Ip6k1 PE=2 SV=1
1.0E-99 [612..963] [61..431]
IP6K3 - inositol hexakisphosphate kinase 3
4.0E-99 [612..961] [53..407]

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Predicted Domain #1
Region A:
Residues: [1-594]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTSHEIHDK IPDTLREQQQ HLRQKESEGC ITTLKDLNVP ETKKLSSVLH GRKASTYLRI  60
   61 FRDDECLADN NNGVDSNNGG SVTCADKITR SEATPKSVPE GLQVSEKKNN PDTLSSSLSS 120
  121 FILSNHEEPA IKPNKHVAHR NNITETGQGS GEDIAKQQSH QPQVLHHQTS LKPIQNVDEG 180
  181 CISPKSTYQE SLHGISEDLT LKPVSSATYY PHKSKADSGY EEKDKMENDI DTIQPATINC 240
  241 ASGIATLPSS YNRHTFKVKT YSTLSQSLRQ ENVNNRSNEK KPQQFVPHSE SIKEKPNTFE 300
  301 QDKEGEQADE EEDEGDNEHR EYPLAVELKP FTNRVGGHTA IFRFSKRAVC KALVNRENRW 360
  361 YENIELCHKE LLQFMPRYIG VLNVRQHFQS KDDFLSDLDQ ENNGKNDTSN ENKDIEVNHN 420
  421 NNDDIALNTE PTGTPLTHIH SFPLEHSSRQ VLEKEHPEIE SVHPHVKRSL SSSNQPSLLP 480
  481 EVVLNDNRHI IPESLWYKYS DSPNSAPNDS YFSSSSSHNS CSFGERGNTN KLKRRDSGST 540
  541 MINTELKNLV IREVFAPKCF RRKRNSNTTT MGNHNARLGS SPSFLTQKSR ASSH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [595-986]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DASNTSMKTL GDSSSQASLQ MDDSKVNPNL QDPFLKKSLH EKISNALDGS HSVMDLKQFH  60
   61 KNEQIKHKNS FCNSLSPILT ATNSRDDGEF ATSPNYISNA QDGVFDMDED TGNETINMDN 120
  121 HGCHLDSGKN MIIKSLAYNV SNDYSHHDIE SITFEETSHT IVSKFILLED LTRNMNKPCA 180
  181 LDLKMGTRQY GVDAKRAKQL SQRAKCLKTT SRRLGVRICG LKVWNKDYYI TRDKYFGRRV 240
  241 KVGWQFARVL ARFLYDGKTI ESLIRQIPRL IKQLDTLYSE IFNLKGYRLY GASLLLMYDG 300
  301 DANKSNSKRK KAANVKVNLI DFARCVTKED AMECMDKFRI PPKSPNIEDK GFLRGVKSLR 360
  361 FYLLLIWNYL TSDMPLIFDE VEMNDMISEE AD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 23.040959
Match: PF03770
Description: Inositol polyphosphate kinase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [987-1050]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSFTSATGS KINFNSKWDW LDEFDKEDEE MYNDPNSKLR QKWRKYELIF DAEPRYNDDA  60
   61 QVSD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [965-1050]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSDMPLIFDE VEMNDMISEE ADSNSFTSAT GSKINFNSKW DWLDEFDKED EEMYNDPNSK  60
   61 LRQKWRKYEL IFDAEPRYND DAQVSD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle