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View Structure Prediction Details

Protein: RAD61
Organism: Saccharomyces cerevisiae
Length: 647 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAD61.

Description E-value Query
Range
Subject
Range
RAD61 - Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Ec...
gi|151942003 - gi|151942003|gb|EDN60359.1| radiation sensitive protein [Saccharomyces cerevisiae YJM789]
RAD61_YEAST - Protein RAD61 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RAD61 PE=1 SV=1
0.0 [1..647] [1..647]
gi|18026950 - gi|18026950|gb|AAL55708.1| RAD3-like DNA helicase [Plasmodium falciparum]
8.0E-81 [75..310] [108..335]

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Predicted Domain #1
Region A:
Residues: [1-74]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAYGKRGPV LRTPFRSNKG LPSSSDVEFS DDDVNSVIPD VSSTISSSIA DHPIEGLLDE  60
   61 PRKAQDSSSS FDGA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.260 a.4.5 "Winged helix" DNA-binding domain
View Download 0.259 a.4.1 Homeodomain-like
View Download 0.337 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.273 a.64.1 Saposin
View Download 0.236 a.4.5 "Winged helix" DNA-binding domain
View Download 0.218 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70

Predicted Domain #2
Region A:
Residues: [75-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEKPSSQLDS KRNDQNVKII TSSDTSMAFM KDEKLSAFNF LDGSKASKRK RRRTYQKHDA  60
   61 NITSSIEPDV QDEDSITMHN EFESIRKIYN DINEFILKLP RADDDILNKM LENEMKMDDS 120
  121 IENNSIRTSK DKKYGKFRTI LINKNKENEI MGEEVDQKAN TLSLNNADNS NAEKEGLTST 180
  181 NHYNELKNMG DTIKYQDDIE FLLSNSKSND NTTVPINEYF KKLLNLSLMI INDEEFFQYA 240
  241 KRYFKKEIIK LSFAQFRSDF PELILLQGYL LHKVSESQSD 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [355-647]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPPSFDNFSI ELSKDDGKIR TKKNKHIKKL SHLNFEDFLR KTQFKTGLYY SLSLWEMHGN  60
   61 LSLDIIKRIS ILASNKDLFS RHVKTFIPLL EKLITASEFC HMYIEQPEMF DSLISNLNNQ 120
  121 FKDMLDDDSL IKILILLTNM EVHNYTLWKE ADMIFQSSMN TILESIHPLT DAKVDNILLH 180
  181 LGLCLNICSR ENSRLKLDGK LWYDMKTIFV KMIRDGSDTE NRLVQGLFYL NFSFLIKQRK 240
  241 ENSNLDPGEL NLLLVELEAF KSETSQFNEG ISNKIEIALN YLKSIYTSER ITI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle