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View Structure Prediction Details

Protein: SOR2
Organism: Saccharomyces cerevisiae
Length: 357 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SOR2.

Description E-value Query
Range
Subject
Range
gi|2570190 - gi|2570190|dbj|BAA22979.1| alcohol dehydrogenase [Arabidopsis thaliana]
0.0 [3..355] [8..377]
gi|6684358 - gi|6684358|gb|AAF23540.1|AF110442_1 alcohol dehydrogenase [Arabidopsis halleri]
0.0 [2..355] [7..377]
gi|6684357 - gi|6684357|gb|AAF23539.1|AF110441_1 alcohol dehydrogenase [Halimolobos perplexa var. lemhiensis]
0.0 [3..355] [8..377]
gi|2570182, gi|2... - gi|2570182|dbj|BAA22976.1| alcohol dehydrogenase [Arabidopsis halleri subsp. gemmifera], gi|2570176|...
0.0 [3..355] [8..377]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQNSNPAVV LEKVGDIAIE QRPIPTIKDP HYVKLAIKAT GICGSDIHYY RSGGIGKYIL  60
   61 KAPMVLGHES SGQVVEVGDA VTRVKVGDRV AIEPGVPSRY SDETKEGSYN LCPHMAFAAT 120
  121 PPIDGTLVKY YLSPEDFLVK LPEGVSYEEG ACVE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [324-357]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LITHKFKFED AAKAYDYNIA HGGEVVKTII FGPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 851.39794
Match: 1e3jA_
Description: Ketose reductase (sorbitol dehydrogenase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ethanol binding 4.47659026306883 bayes_pls_golite062009
NAD or NADH binding 4.35058438816264 bayes_pls_golite062009
retinol dehydrogenase activity 4.1750549780559 bayes_pls_golite062009
oxidoreductase activity 3.09625241707629 bayes_pls_golite062009
methylglyoxal reductase (NADH-dependent) activity 3.00190838171391 bayes_pls_golite062009
L-iditol 2-dehydrogenase activity 3.00103406168296 bayes_pls_golite062009
alcohol binding 2.97042200128883 bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity 2.94416173750168 bayes_pls_golite062009
retinol binding 2.89007863838685 bayes_pls_golite062009
all-trans retinal binding 2.84803957533249 bayes_pls_golite062009
S-(hydroxymethyl)glutathione dehydrogenase activity 2.58673703881996 bayes_pls_golite062009
hydroxymethylfurfural reductase (NADH) activity 2.2999175117758 bayes_pls_golite062009
hydroxymethylfurfural reductase activity 2.2999175117758 bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent 2.26153457113968 bayes_pls_golite062009
NADPH:quinone reductase activity 2.16668841986245 bayes_pls_golite062009
benzaldehyde dehydrogenase activity 2.03039843216597 bayes_pls_golite062009
catalytic activity 1.79741889688267 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 1.65338499044318 bayes_pls_golite062009
DNA binding 1.61355789916908 bayes_pls_golite062009
transcription regulator activity 1.55390653047158 bayes_pls_golite062009
retinoid binding 1.54383322726845 bayes_pls_golite062009
nucleic acid binding 1.48478425318425 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.47309297191111 bayes_pls_golite062009
isoprenoid binding 1.42961392805059 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors 1.38219425408212 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 1.29842732066898 bayes_pls_golite062009
chaperone binding 1.19079350615542 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 1.07006097264025 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 1.01627645289834 bayes_pls_golite062009
binding 0.982999356179965 bayes_pls_golite062009
transcription factor activity 0.91090893050278 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.527946013169731 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.484089941059577 bayes_pls_golite062009
kinase activity 0.461063813999598 bayes_pls_golite062009
hydrolase activity 0.41684292392606 bayes_pls_golite062009
hydroxymethylfurfural reductase (NADPH) activity 0.382131941157781 bayes_pls_golite062009
L-arabinitol 2-dehydrogenase activity 0.382131941157781 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.375415252607746 bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity 0.361275519814065 bayes_pls_golite062009
coenzyme binding 0.35922330382799 bayes_pls_golite062009
structural molecule activity 0.345975336806588 bayes_pls_golite062009
protein kinase activity 0.339420053437627 bayes_pls_golite062009
3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity 0.320177384202291 bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase activity 0.298691872199351 bayes_pls_golite062009
ATPase activity 0.275256680720412 bayes_pls_golite062009
enoyl-CoA hydratase activity 0.250698007650211 bayes_pls_golite062009
methylenetetrahydrofolate dehydrogenase activity 0.169301675015808 bayes_pls_golite062009
methenyltetrahydrofolate cyclohydrolase activity 0.162625185692811 bayes_pls_golite062009
fatty acid synthase activity 0.0962368786590111 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [155-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLSVGVHSNK LAGVRFGTKV VVFGAGPVGL LTGAVARAFG ATDVIFVDVF DNKLQRAKDF  60
   61 GATNTFNSSQ FSTDKAQDLA DGVQKLLGGN HADVVFECSG ADVCIDAAVK TTKVGGTMVQ 120
  121 VGMGKNYTNF PIAEVSGKEM KLIGCFRYSF GDYRDAVNLV ATGKVNVKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 851.39794
Match: 1e3jA_
Description: Ketose reductase (sorbitol dehydrogenase)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle