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View Structure Prediction Details

Protein: CDC48
Organism: Saccharomyces cerevisiae
Length: 835 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC48.

Description E-value Query
Range
Subject
Range
CDC48_SOYBN - Cell division cycle protein 48 homolog OS=Glycine max GN=CDC48 PE=2 SV=1
0.0 [19..835] [14..807]
CD48D_ARATH - Cell division control protein 48 homolog D OS=Arabidopsis thaliana GN=CDC48D PE=1 SV=1
0.0 [19..835] [14..815]
CDC48_YEAST - Cell division control protein 48 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC48 P...
CDC48 - ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a complex with Npl4p a...
0.0 [2..835] [2..835]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [11..811] [38..825]
CDC48_CAPAN - Cell division cycle protein 48 homolog OS=Capsicum annuum GN=CAFP PE=2 SV=1
0.0 [16..835] [11..805]
TER94-PA - The gene TER94 is referred to in FlyBase by the symbol Dmel\TER94 (CG2331, FBgn0261014). It is a pro...
gi|220942716 - gi|220942716|gb|ACL83901.1| TER94-PA [synthetic construct]
0.0 [20..835] [7..801]
gi|4996891, gi|6... - gi|60465285|gb|EAL63377.1| cell division cycle protein 48 [Dictyostelium discoideum], gi|4996891|gb|...
gi|60465285, gi|... - gi|66806375|ref|XP_636910.1| cell division cycle protein 48 [Dictyostelium discoideum AX4], gi|60465...
0.0 [26..798] [15..775]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEEHKPLLD ASGVDPREED KTATAILRRK KKDNMLLVDD AINDDNSVIA INSNTMDKLE  60
   61 LFRGDTVLVK GKKRKDTVLI VLIDDELEDG ACRINRVVRN NLRIRLGDLV TIHPCPD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10138.0
Match: 1e32A_
Description: Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [118-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKYATRISVL PIADTIEGIT GNLFDVFLKP YFVEAYRPVR KGDHFVVRGG MRQVEFKVVD  60
   61 VEPEEYAVVA QDTIIHWEGE PINREDEENN MNE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10138.0
Match: 1e32A_
Description: Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [211-381]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGYDDIGGCR KQMAQIREMV ELPLRHPQLF KAIGIKPPRG VLMYGPPGTG KTLMARAVAN  60
   61 ETGAFFFLIN GPEVMSKMAG ESESNLRKAF EEAEKNAPAI IFIDEIDSIA PKRDKTNGEV 120
  121 ERRVVSQLLT LMDGMKARSN VVVIAATNRP NSIDPALRRF GRFDREVDIG I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10138.0
Match: 1e32A_
Description: Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [382-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDATGRLEVL RIHTKNMKLA DDVDLEALAA ETHGYVGADI ASLCSEAAMQ QIREKMDLID  60
   61 LDEDEIDAEV LDSLGVTM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10138.0
Match: 1e32A_
Description: Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [460-641]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNFRFALGNS NPSALRETVV ESVNVTWDDV GGLDEIKEEL KETVEYPVLH PDQYTKFGLS  60
   61 PSKGVLFYGP PGTGKTLLAK AVATEVSANF ISVKGPELLS MWYGESESNI RDIFDKARAA 120
  121 APTVVFLDEL DSIAKARGGS LGDAGGASDR VVNQLLTEMD GMNAKKNVFV IGATNRPDQI 180
  181 DP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.751666
Match: 1d2nA_
Description: Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [642-725]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AILRPGRLDQ LIYVPLPDEN ARLSILNAQL RKTPLEPGLE LTAIAKATQG FSGADLLYIV  60
   61 QRAAKYAIKD SIEAHRQHEA EKEV

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.93
Match: 1d2nA
Description: Hexamerization domain of N-ethylmalemide-sensitive fusion (NSF) protein
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [726-835]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVEGEDVEMT DEGAKAEQEP EVDPVPYITK EHFAEAMKTA KRSVSDAELR RYEAYSQQMK  60
   61 ASRGQFSNFN FNDAPLGTTA TDNANSNNSA PSGAGAAFGS NAEEDDDLYS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.272 0.179 ER-associated protein catabolic process a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.289 0.030 protein transport b.88.1 Mss4-like
View Download 0.324 0.022 ER-associated protein catabolic process a.116.1 GTPase activation domain, GAP
View Download 0.259 0.003 ER-associated protein catabolic process a.142.1 PTS-regulatory domain, PRD
View Download 0.236 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.232 N/A N/A a.142.1 PTS-regulatory domain, PRD
View Download 0.231 N/A N/A f.27.1 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.204 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.203 N/A N/A c.47.1 Thioredoxin-like
View Download 0.201 N/A N/A a.74.1 Cyclin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle