YRC Public Data Repository - Protein Structure Prediction

Protein:	QRI7
Organism:	Saccharomyces cerevisiae
Length:	407 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for QRI7.

Description	E-value	Query Range	Subject Range
QRI7_YEAST - tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial OS=Saccharomyces cerevisiae (strain AT... QRI7 - Highly conserved mitochondrial protein, essential for stability of the mitochondrial genome; functio...	0.0	[1..407]	[1..407]
gi\|15603103, gi\|... - gi\|15603103\|ref\|NP_246175.1\| O-sialoglycoprotein endopeptidase [Pasteurella multocida subsp. multoci...	0.0	[33..400]	[1..343]
GCP_HAEIN - Probable O-sialoglycoprotein endopeptidase OS=Haemophilus influenzae GN=gcp PE=3 SV=1 TSAD_HAEIN - tRNA N6-adenosine threonylcarbamoyltransferase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11...	0.0	[33..399]	[1..342]
GCP_HAEDU - Probable O-sialoglycoprotein endopeptidase OS=Haemophilus ducreyi GN=gcp PE=3 SV=1 TSAD_HAEDU - tRNA N6-adenosine threonylcarbamoyltransferase OS=Haemophilus ducreyi (strain 35000HP / ATCC 700724)...	0.0	[33..399]	[1..342]
TSAD_SALTY - tRNA N6-adenosine threonylcarbamoyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / AT... TSAD_SALG2 - tRNA N6-adenosine threonylcarbamoyltransferase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346)... gi\|200387093, gi... - gi\|200387093\|ref\|ZP_03213705.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enteri... TSAD_SALDC - tRNA N6-adenosine threonylcarbamoyltransferase OS=Salmonella dublin (strain CT_02021853) GN=tsaD PE=... gi\|197265256, gi... - gi\|197265256\|ref\|ZP_03165330.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enteri... lcl\|NC_016856.1_... - [gene=gcp] [protein=O-sialoglycoprotein endopeptidase] [protein_id=YP_005239384.1] [location=complem... TSAD_SALEP - tRNA N6-adenosine threonylcarbamoyltransferase OS=Salmonella enteritidis PT4 (strain P125109) GN=tsa... gi\|167990238, gi... - gi\|205331153\|gb\|EDZ17917.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enterica s... GCP_SALTY - Probable O-sialoglycoprotein endopeptidase OS=Salmonella typhimurium GN=gcp PE=3 SV=2 GCP_SALTY - Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp OS=Salmonella typhimurium GN=gcp P... TSAD_SALA4 - tRNA N6-adenosine threonylcarbamoyltransferase OS=Salmonella agona (strain SL483) GN=tsaD PE=3 SV=1 TSAD_SALHS - tRNA N6-adenosine threonylcarbamoyltransferase OS=Salmonella heidelberg (strain SL476) GN=tsaD PE=3 ... gi\|205348610, gi... - gi\|205348610\|gb\|EDZ35241.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enterica s... gi\|205337810, gi... - gi\|205337810\|gb\|EDZ24574.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enterica s...	0.0	[33..398]	[1..336]
gi\|213616355 - gi\|213616355\|ref\|ZP_03372181.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enteri... GCP_SALTI - Probable O-sialoglycoprotein endopeptidase OS=Salmonella typhi GN=gcp PE=3 SV=1 gi\|213161046 - gi\|213161046\|ref\|ZP_03346756.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enteri... gi\|214001818 - gi\|214001818\|ref\|ZP_03412553.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enteri... gi\|213646109 - gi\|213646109\|ref\|ZP_03376162.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enteri... gi\|16761982 - gi\|16761982\|ref\|NP_457599.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enterica ... TSAD_SALTI - tRNA N6-adenosine threonylcarbamoyltransferase OS=Salmonella typhi GN=tsaD PE=3 SV=1 gi\|29143469, gi\|... - gi\|29143469\|ref\|NP_806811.1\| O-sialoglycoprotein endopeptidase [Salmonella enterica subsp. enterica ...	3.0E-99	[33..398]	[1..336]
gi\|13363420, gi\|... - gi\|15833201\|ref\|NP_311974.1\| putative DNA-binding/iron metalloprotein/AP endonuclease [Escherichia c... gi\|217327754, gi... - gi\|217327754\|ref\|ZP_03443837.1\| O-sialoglycoprotein endopeptidase [Escherichia coli O157:H7 str. TW1... TSAD_ECO57 - tRNA N6-adenosine threonylcarbamoyltransferase OS=Escherichia coli O157:H7 GN=tsaD PE=3 SV=1 gi\|209759260, gi... - pir\|\|B85967 probable O-sialoglycoprotein endopeptidase ygjD [imported] - Escherichia coli (strain O1... gi\|12517643, gi\|... - gi\|15803606\|ref\|NP_289639.1\| O-sialoglycoprotein endopeptidase [Escherichia coli O157:H7 EDL933], gi...	3.0E-99	[33..398]	[1..336]
EG11171 - tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; glycation binding protein / tRNA(... EG11171 - tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; glycation binding protein / tRNA(... GCP_ECOLI - Probable O-sialoglycoprotein endopeptidase (EC 3.4.24.57) (Glycoprotease) - Escherichia coli TSAD_ECOBW - tRNA N6-adenosine threonylcarbamoyltransferase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN... gi\|251786341, gi... - gi\|251786341\|ref\|YP_003000645.1\| hypothetical protein B21_02884 [Escherichia coli BL21], gi\|24237861... TSAD_ECODH - tRNA N6-adenosine threonylcarbamoyltransferase OS=Escherichia coli (strain K12 / DH10B) GN=tsaD PE=3... gi\|253323144, gi... - gi\|254289761\|ref\|YP_003055509.1\| O-sialoglycoprotein endopeptidase [Escherichia coli BL21(DE3)], gi\|... TSAD_ECOLU - tRNA N6-adenosine threonylcarbamoyltransferase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPE... gi\|226839857, gi... - gi\|254038233\|ref\|ZP_04872291.1\| peptidase [Escherichia sp. 1_1_43], gi\|226839857\|gb\|EEH71878.1\| pept... gi\|253974912, gi... - gi\|254163011\|ref\|YP_003046119.1\| O-sialoglycoprotein endopeptidase [Escherichia coli B str. REL606],... gi\|83587498 - gi\|83587498\|ref\|ZP_00926125.1\| COG0533: Metal-dependent proteases with possible chaperone activity [... TSAD_SHIDS - tRNA N6-adenosine threonylcarbamoyltransferase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=... gi\|89109834, gi\|... - gi\|89109834\|ref\|AP_003614.1\| predicted peptidase [Escherichia coli str. K-12 substr. W3110], gi\|8567...	5.0E-99	[33..398]	[1..336]
TSAD_MANHA - tRNA N6-adenosine threonylcarbamoyltransferase OS=Mannheimia haemolytica GN=tsaD PE=1 SV=1	8.0E-99	[33..375]	[1..319]
TSAD_PSEAE - tRNA N6-adenosine threonylcarbamoyltransferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /... GCP_PSEAE - Probable O-sialoglycoprotein endopeptidase OS=Pseudomonas aeruginosa GN=gcp PE=3 SV=1	1.0E-98	[33..399]	[1..341]

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Predicted Domain #1

Region A:
Residues: [1-75]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISIKGTGRF LLDNYRIWQR RAFNRPIQLR KGYKVLAIET SCDDTCVSVL DRFSKSAAPN  60
   61 VLANLKDTLD SIDEG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.742	0.009	mitochondrion	b.84.2	Rudiment single hybrid motif
View	Download	0.886	0.009	mitochondrion	d.58.7	RNA-binding domain, RBD
View	Download	0.742	0.009	mitochondrion	d.58.5	GlnB-like
View	Download	0.695	0.009	mitochondrion	d.58.18	Regulatory domain in the aminoacid metabolism
View	Download	0.670	0.009	mitochondrion	d.58.24	CheY-binding domain of CheA
View	Download	0.668	0.009	mitochondrion	d.58.1	4Fe-4S ferredoxins
View	Download	0.655	0.009	mitochondrion	b.84.2	Rudiment single hybrid motif
View	Download	0.647	0.009	mitochondrion	d.58.10	Acylphosphatase-like
View	Download	0.578	0.009	mitochondrion	d.58.24	CheY-binding domain of CheA
View	Download	0.555	0.009	mitochondrion	d.58.11	EF-G/eEF-2 domains III and V
View	Download	0.515	0.009	mitochondrion	d.58.17	Metal-binding domain
View	Download	0.509	0.009	mitochondrion	d.58.18	Regulatory domain in the aminoacid metabolism
View	Download	0.492	0.009	mitochondrion	d.58.23	Probable ACP-binding domain of malonyl-CoA ACP transacylase
View	Download	0.476	0.009	mitochondrion	b.84.2	Rudiment single hybrid motif
View	Download	0.457	0.009	mitochondrion	d.58.49	YajQ-like
View	Download	0.457	0.009	mitochondrion	a.60.1	SAM/Pointed domain
View	Download	0.443	0.009	mitochondrion	d.58.3	Protease propeptides/inhibitors
View	Download	0.443	0.009	mitochondrion	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View	Download	0.439	0.009	mitochondrion	a.35.1	lambda repressor-like DNA-binding domains
View	Download	0.431	0.009	mitochondrion	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.429	0.009	mitochondrion	d.51.1	Eukaryotic type KH-domain (KH-domain type I)
View	Download	0.422	0.009	mitochondrion	a.24.7	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View	Download	0.416	0.009	mitochondrion	d.58.4	Dimeric alpha+beta barrel
View	Download	0.412	0.009	mitochondrion	d.137.1	Monooxygenase (hydroxylase) regulatory protein
View	Download	0.407	0.009	mitochondrion	d.58.7	RNA-binding domain, RBD
View	Download	0.404	0.009	mitochondrion	d.58.1	4Fe-4S ferredoxins
View	Download	0.398	0.009	mitochondrion	d.57.1	DNA damage-inducible protein DinI
View	Download	0.391	0.009	mitochondrion	d.58.24	CheY-binding domain of CheA
View	Download	0.383	0.009	mitochondrion	d.58.25	Killer toxin KP6 alpha-subunit
View	Download	0.382	0.009	mitochondrion	d.58.5	GlnB-like
View	Download	0.381	0.009	mitochondrion	d.58.5	GlnB-like
View	Download	0.365	0.009	mitochondrion	d.58.7	RNA-binding domain, RBD
View	Download	0.363	0.009	mitochondrion	b.84.2	Rudiment single hybrid motif
View	Download	0.356	0.009	mitochondrion	d.205.1	GTP cyclohydrolase I feedback regulatory protein, GFRP
View	Download	0.356	0.009	mitochondrion	d.58.17	Metal-binding domain
View	Download	0.346	0.009	mitochondrion	d.58.5	GlnB-like
View	Download	0.346	0.009	mitochondrion	b.40.2	Bacterial enterotoxins
View	Download	0.343	0.009	mitochondrion	a.156.1	S13-like H2TH domain
View	Download	0.340	0.009	mitochondrion	b.1.2	Fibronectin type III
View	Download	0.338	0.009	mitochondrion	b.84.2	Rudiment single hybrid motif
View	Download	0.330	0.009	mitochondrion	b.84.2	Rudiment single hybrid motif
View	Download	0.329	0.009	mitochondrion	d.58.38	Urease metallochaperone UreE, C-terminal domain
View	Download	0.328	0.009	mitochondrion	d.58.40	D-ribose-5-phosphate isomerase (RpiA), lid domain
View	Download	0.325	0.009	mitochondrion	b.84.1	Single hybrid motif
View	Download	0.324	0.009	mitochondrion	d.58.23	Probable ACP-binding domain of malonyl-CoA ACP transacylase
View	Download	0.319	0.009	mitochondrion	d.58.1	4Fe-4S ferredoxins
View	Download	0.319	0.009	mitochondrion	b.84.2	Rudiment single hybrid motif
View	Download	0.307	0.009	mitochondrion	a.50.1	Anaphylotoxins (complement system)
View	Download	0.303	0.009	mitochondrion	d.205.1	GTP cyclohydrolase I feedback regulatory protein, GFRP
View	Download	0.303	0.009	mitochondrion	d.16.1	FAD-linked reductases, C-terminal domain
View	Download	0.299	0.009	mitochondrion	b.84.2	Rudiment single hybrid motif
View	Download	0.298	0.009	mitochondrion	c.47.1	Thioredoxin-like
View	Download	0.294	0.009	mitochondrion	d.58.24	CheY-binding domain of CheA
View	Download	0.286	0.009	mitochondrion	d.16.1	FAD-linked reductases, C-terminal domain
View	Download	0.277	0.009	mitochondrion	d.58.18	Regulatory domain in the aminoacid metabolism
View	Download	0.277	0.009	mitochondrion	d.16.1	FAD-linked reductases, C-terminal domain
View	Download	0.276	0.009	mitochondrion	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.272	0.009	mitochondrion	a.60.13	Putative methyltransferase TM0872, insert domain
View	Download	0.263	0.009	mitochondrion	d.137.1	Monooxygenase (hydroxylase) regulatory protein
View	Download	0.260	0.009	mitochondrion	c.55.7	Methylated DNA-protein cysteine methyltransferase domain
View	Download	0.254	0.009	mitochondrion	a.60.1	SAM/Pointed domain
View	Download	0.252	0.009	mitochondrion	d.58.1	4Fe-4S ferredoxins
View	Download	0.250	0.009	mitochondrion	a.4.1	Homeodomain-like
View	Download	0.246	0.009	mitochondrion	d.87.1	FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View	Download	0.243	0.009	mitochondrion	b.55.1	PH domain-like
View	Download	0.240	0.009	mitochondrion	a.61.1	Retroviral matrix proteins
View	Download	0.238	0.009	mitochondrion	a.77.1	DEATH domain
View	Download	0.237	0.009	mitochondrion	d.58.24	CheY-binding domain of CheA
View	Download	0.236	0.009	mitochondrion	d.58.12	eEF-1beta-like
View	Download	0.235	0.009	mitochondrion	a.47.2	t-snare proteins
View	Download	0.234	0.009	mitochondrion	b.1.1	Immunoglobulin
View	Download	0.233	0.009	mitochondrion	d.58.14	Ribosomal protein S6
View	Download	0.231	0.009	mitochondrion	a.60.1	SAM/Pointed domain
View	Download	0.230	0.009	mitochondrion	d.95.2	Homing endonucleases
View	Download	0.218	0.009	mitochondrion	a.144.1	PABC (PABP) domain
View	Download	0.214	0.009	mitochondrion	a.4.1	Homeodomain-like
View	Download	0.211	0.009	mitochondrion	a.7.6	Ribosomal protein S20
View	Download	0.211	0.009	mitochondrion	a.118.1	ARM repeat
View	Download	0.207	0.009	mitochondrion	a.151.1	Glutamyl tRNA-reductase dimerization domain
View	Download	0.203	0.009	mitochondrion	b.55.1	PH domain-like
View	Download	0.202	0.009	mitochondrion	d.58.11	EF-G/eEF-2 domains III and V
View	Download	0.201	0.009	mitochondrion	a.24.10	Histidine-containing phosphotransfer domain, HPT domain
View	Download	0.200	0.009	mitochondrion	a.85.1	Hemocyanin, N-terminal domain

Predicted Domain #2

Region A:
Residues: [76-407]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIIPTKAHIH HQARIGPLTE RALIESNARE GIDLICVTRG PGMPGSLSGG LDFAKGLAVA  60
   61 WNKPLIGVHH MLGHLLIPRM GTNGKVPQFP FVSLLVSGGH TTFVLSRAID DHEILCDTID 120
  121 IAVGDSLDKC GRELGFKGTM IAREMEKFIN QDINDQDFAL KLEMPSPLKN SASKRNMLSF 180
  181 SFSAFITALR TNLTKLGKTE IQELPEREIR SIAYQVQESV FDHIINKLKH VLKSQPEKFK 240
  241 NVREFVCSGG VSSNQRLRTK LETELGTLNS TSFFNFYYPP MDLCSDNSIM IGWAGIEIWE 300
  301 SLRLVSDLDI CPIRQWPLND LLSVDGWRTD QL

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	9.44
Match:	1jceA
Description:	Prokaryotic actin homolog MreB
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits