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View Structure Prediction Details

Protein: MDH3
Organism: Saccharomyces cerevisiae
Length: 343 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MDH3.

Description E-value Query
Range		 Subject
Range
gi|17368677, gi|... - gi|17368677|sp|Q9BE24|LDHA_MACFA L-lactate dehydrogenase A chain (LDH-A) (LDH muscle subunit) (LDH-M...
 0.0 [3..336] [22..332]
LDHA - lactate dehydrogenase A
 0.0 [3..336] [21..331]
gi|55249958 - gb|AAH86251.1| Unknown (protein for MGC:98768) [Xenopus laevis]
LDHA_MOUSE - L-lactate dehydrogenase A chain OS=Mus musculus GN=Ldha PE=1 SV=3
 1.0E-99 [3..336] [22..332]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 2.0E-99 [3..336] [22..332]
LDHA_RABIT - L-lactate dehydrogenase A chain OS=Oryctolagus cuniculus GN=LDHA PE=1 SV=3
 3.0E-99 [3..336] [22..332]
LDHA_RAT - L-lactate dehydrogenase A chain OS=Rattus norvegicus GN=Ldha PE=1 SV=1
 8.0E-99 [3..336] [22..332]
LDHA_PIG - L-lactate dehydrogenase A chain OS=Sus scrofa GN=LDHA PE=1 SV=3
gi|473571 - gi|473571|gb|AAA50436.1| lactate dehydrogenase-A
 5.0E-98 [3..336] [22..332]
LDHA_MONDO - L-lactate dehydrogenase A chain OS=Monodelphis domestica GN=LDHA PE=2 SV=3
 5.0E-98 [3..336] [22..332]

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Predicted Domain #1
Region A:
Residues: [1-343] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKVAILGAS GGVGQPLSLL LKLSPYVSEL ALYDIRAAEG IGKDLSHINT NSSCVGYDKD  60
   61 SIENTLSNAQ VVLIPAGVPR KPGLTRDDLF KMNAGIVKSL VTAVGKFAPN ARILVISNPV 120
  121 NSLVPIAVET LKKMGKFKPG NVMGVTNLDL VRAETFLVDY LMLKNPKIGQ EQDKTTMHRK 180
  181 VTVIGGHSGE TIIPIITDKS LVFQLDKQYE HFIHRVQFGG DEIVKAKQGA GSATLSMAFA 240
  241 GAKFAEEVLR SFHNEKPETE SLSAFVYLPG LKNGKKAQQL VGDNSIEYFS LPIVLRNGSV 300
  301 VSIDTSVLEK LSPREEQLVN TAVKELRKNI EKGKSFILDS SKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 731.751666
Match: 1mldA_
Description: Malate dehydrogenase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle