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View Structure Prediction Details

Protein: RPN4
Organism: Saccharomyces cerevisiae
Length: 531 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPN4.

Description E-value Query
Range
Subject
Range
RPN4 - Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regula...
RPN4_YEAST - Protein RPN4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPN4 PE=1 SV=1
0.0 [1..531] [1..531]
gi|38382750, gi|... - gi|38382750|gb|AAH62309.1| Zinc finger protein 79 [Homo sapiens], gi|24307937|ref|NP_009066.1| zinc ...
gi|208968181 - gi|208968181|dbj|BAG73929.1| zinc finger protein 79 [synthetic construct]
0.0 [139..525] [78..458]

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Predicted Domain #1
Region A:
Residues: [1-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTELSLKR TLTDILEDEL YHTNPGHSQF TSHYQNYHPN ASITPYKLVN KNKENNTFTW  60
   61 NHSLQHQNES SAASIPPQQT YHFPIFNKYA DPTLTTTTSF TTSEATANDR QINNVHLIPN 120
  121 EIKGASETPL QKTVNLKNIM KVSDPYVPTR NTFNYDVKIS NDFFDNGDNL YGNDEEVLFY 180
  181 EDNYNPKMQW SLQDNSAAIN NEDARAIFNN EFDSDDDDIS DDEEDEIEEN CLQQEQHQEE 240
  241 PLLSLDVTPI SMFGSDQKTG RAKSSSHLFN EYSYVDSNMD SISSVVSEDL LDERGHEKIE 300
  301 DEDED

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [306-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDLDEDDIYD ISLLKNRRKQ SFVLNKNTID FERFPSPSTS ANVPSTATTG KRKPAKSSSN  60
   61 RSCVSNSNEN GT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.045757
Match: 1meyG_
Description: Designed zinc finger protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [378-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LERIKKPTSA VVSSNASRRK LINYTKKHLS SHSSTNSNSK PSTASPSAHT SSSDGNNEIF  60
   61 TCQIMNLIT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.69897
Match: 1tf3A_
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [447-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEPCGAQFSR SYDLTRHQNT IHAKRKIVFR CSECIKILGS EGYQKTFSRL DALTRHIKSK  60
   61 HEDLSLEQRQ EVTKFAKANI GYVMG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 44.529817
Match: 1a1iA_
Description: ZIF268
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle