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View Structure Prediction Details

Protein: APC11
Organism: Saccharomyces cerevisiae
Length: 165 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APC11.

Description E-value Query
Range
Subject
Range
APC11_YEAST - Anaphase-promoting complex subunit 11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AP...
APC11 - Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-pro...
1.0E-37 [1..165] [1..165]
gi|16416109 - gi|16416109|emb|CAB92694.2| conserved hypothetical protein [Neurospora crassa]
4.0E-20 [21..159] [335..465]
gi|6729030 - gi|6729030|gb|AAF27026.1|AC009177_16 putative RING-H2 zinc finger protein ATL6 [Arabidopsis thaliana...
3.0E-18 [20..154] [92..227]
gi|149055047, gi... - gi|186910259|ref|NP_001119554.1| anaphase promoting complex subunit 11 homolog [Rattus norvegicus], ...
APC11_MOUSE - Anaphase-promoting complex subunit 11 OS=Mus musculus GN=Anapc11 PE=3 SV=1
gi|149723427 - gi|149723427|ref|XP_001488245.1| PREDICTED: similar to anaphase promoting complex subunit 11 homolog...
5.0E-17 [1..102] [1..84]

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Predicted Domain #1
Region A:
Residues: [1-165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVKINEVHS VFAWSWHIPS TSDEDAANND PIGNDEDEDV CGICRASYNG TCPSCKFPGD  60
   61 QCPLVIGLCH HNFHDHCIYR WLDTPTSKGL CPMCRQTFQL QKGLAINDAH VQKFVEIVSR 120
  121 RREEMIEEGV AEEFVDFDEP IRQNTDNPIG RQQVDTILDE DFLLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.68867
Match: 1ldjB_
Description: RIGG-box protein 1 (RBX1) of SCF ubiquitin ligase complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 10.2497392096259 bayes_pls_golite062009
small conjugating protein ligase activity 10.0460587929138 bayes_pls_golite062009
acid-amino acid ligase activity 8.99384576623969 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 7.6988425139962 bayes_pls_golite062009
ligase activity 3.92677358871643 bayes_pls_golite062009
binding 2.58862749918018 bayes_pls_golite062009
NEDD8 ligase activity 2.41658628840288 bayes_pls_golite062009
protein binding 1.49775478023418 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
nucleic acid binding 0.708499177773075 bayes_pls_golite062009
transcription regulator activity 0.681643203460463 bayes_pls_golite062009
hydrolase activity 0.52386813728704 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.392372133643049 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
DNA binding 0.227671243150662 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
enzyme binding 0.104373352314595 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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