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View Structure Prediction Details

Protein: KIN82
Organism: Saccharomyces cerevisiae
Length: 720 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KIN82.

Description E-value Query
Range
Subject
Range
KIN82 - Putative serine/threonine protein kinase implicated in the regulation of phospholipid asymmetry thro...
0.0 [1..720] [1..720]
gi|13537204, gi|... - gi|14149671|ref|NP_055927.1| microtubule associated serine/threonine kinase 2 [Homo sapiens], gi|135...
0.0 [2..694] [191..880]
gi|5757703, gi|9... - gi|9910296|ref|NP_064329.1| microtubule associated serine/threonine kinase 1 [Mus musculus], gi|5757...
0.0 [2..690] [51..737]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [8..662] [102..759]
gi|7339534 - gi|7339534|emb|CAB82852.1| protein kinase MK6 [Mesembryanthemum crystallinum]
0.0 [217..718] [12..546]

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Predicted Domain #1
Region A:
Residues: [1-175]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQQEYRSPS QRLSKGRSMS LPKIFARNLR SLQNNAPPGK NINVNCLNVN SCSLSASPSS  60
   61 QINMACNGNK QDLPIPFPLH VECNDSWSSS KLNKFKSMFN HNRSKSSGTT DASTSEKGTH 120
  121 KREPRSTIHT ELLQSSIIGE PNVHSTTSST LIPNEAICST PNEISGSSSP DAELF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [176-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFDMPTDPSS FHTPSSPSYI AKDSRNLSNG SLNDINENEE LQNFHRKISE NGSASPLANL  60
   61 SLSNSPIDSP RKNSETRKDQ IPMNITPRLR RAASEPFNTA KDGLMREDYI ALKQPPSLGD 120
  121 IVEPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 108.154902
Match: 1qcfA_
Description: Hemapoetic cell kinase Hck; Hemopoetic cell kinase Hck; Haemopoetic cell kinase Hck
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [301-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSRRLRTKSF GNKFQDITVE PQSFEKIRLL GQGDVGKVYL MRERDTNQIF ALKVLNKHEM  60
   61 IKRKKIKRVL TEQE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [387-403]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYHSFQTKDY LYLCMEY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 108.154902
Match: 1qcfA_
Description: Hemapoetic cell kinase Hck; Hemopoetic cell kinase Hck; Haemopoetic cell kinase Hck
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [375-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILATSDHPFI VT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [404-475]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CMGGEFFRAL QTRKSKCIAE EDAKFYASEV VAALEYLHLL GFIYRDLKPE NILLHQSGHV  60
   61 MLSDFDLSIQ AT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 108.154902
Match: 1qcfA_
Description: Hemapoetic cell kinase Hck; Hemopoetic cell kinase Hck; Haemopoetic cell kinase Hck
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [476-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSKKPTMKDS TYLDTKICSD GFRTNSFVGT EEYLAPEVIR GNGHTAAVDW WTLGILIYEM  60
   61 LFGCTPFKGD NSNETFSNIL TKDVKFPHDK EVSKNCKDLI KKLLNKNEAK R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 108.154902
Match: 1qcfA_
Description: Hemapoetic cell kinase Hck; Hemopoetic cell kinase Hck; Haemopoetic cell kinase Hck
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [587-665]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGSKSGAADI KRHPFFKKVQ WSFLRNQDPP LIPALNDNGC ELPFILSCNK HPKRNSVSEQ  60
   61 ETKMFCEKVA NDDEIDEAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 710.9794
Match: 1ctpE_
Description: cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [666-720]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFHDFNSMSL TKKDHNILTY SENYTYGKIL YKATCTRPRH NSSHRSFFKD IIPEL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle