YRC Public Data Repository - Protein Structure Prediction

Protein:	ATG15
Organism:	Saccharomyces cerevisiae
Length:	520 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG15.

Description	E-value	Query Range	Subject Range
gi\|3850137 - gi\|3850137\|emb\|CAA21938.1\| conserved hypothetical protein [Candida albicans]	683.0	[0..40]	[475..40]
ATG15_CANAL - Putative lipase ATG15 OS=Candida albicans GN=ATG15 PE=3 SV=1 ATG15_CANAL - Putative lipase ATG15 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ATG15 PE=3 SV=1	680.0	[0..40]	[475..40]
ATG15_PASFU - Putative lipase ATG15 OS=Passalora fulva GN=ATG15 PE=2 SV=1	595.0	[0..55]	[475..60]
atg15 - triacylglycerol lipase Atg15 ATG15_SCHPO - Putative lipase atg15 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=atg15 PE=3 SV=1	588.0	[0..59]	[473..43]
gi\|50424623, gi\|... - gi\|50424623\|ref\|XP_460901.1\| hypothetical protein DEHA0F13453g [Debaryomyces hansenii CBS767], gi\|49... ATG15_DEBHA - Putative lipase ATG15 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii)	551.0	[0..51]	[517..69]
ATG15_ASHGO - Putative lipase ATG15 OS=Ashbya gossypii GN=ATG15 PE=3 SV=1 ATG15_ASHGO - Putative lipase ATG15 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) ...	528.0	[0..23]	[518..51]
ATG15_KLULA - Putative lipase ATG15 OS=Kluyveromyces lactis GN=ATG15 PE=3 SV=1 ATG15_KLULA - Putative lipase ATG15 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /...	528.0	[0..57]	[518..60]
ATG15_YARLI - Putative lipase ATG15 OS=Yarrowia lipolytica GN=ATG15 PE=3 SV=2 ATG15_YARLI - Putative lipase ATG15 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=ATG15 PE=3 SV=2	497.0	[0..54]	[519..65]
gi\|50555333, gi\|... - gi\|50555333\|ref\|XP_505075.1\| hypothetical protein [Yarrowia lipolytica], gi\|49650945\|emb\|CAG77882.1\|...	497.0	[0..54]	[519..75]
AT151_PHANO - Putative lipase ATG15-1 OS=Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) GN=ATG15... AT151_PHANO - Putative lipase ATG15-1 OS=Phaeosphaeria nodorum GN=ATG15-1 PE=3 SV=1	479.0	[0..52]	[513..43]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHKSPSRKR FASPLHLGCI LTLTVLCLIA YYFALPDYLS VGKSSSRGAM DQKSDGTFRL  60
   61 KSIYRHGVGA NHRLHQRLEV TPEVISAAGM LYQETTTQGQ DFEDQEPLWT TNAEYATTNP 120
  121 FDFEFELRRM PLLMKRMKER DPEFIESYIY GETYMTEEEE HAMWIDDDIV APNITDRGTV 180
  181 VSLALMSSNA YVRIPQTGDW RNVTEPWNET EPEDFGWDGD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [221-371]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIRGHVFYNE VENIVVLSIK GTSAQGLPGS GEDETTGNDK INDNLLFSCC CARVSYLWTT  60
   61 VCDCYVKSYI CDESCLEKEL RRKDRFYSAV VDIYKGVLKE YPDAAIWVTG HSLGGALASL 120
  121 LGRTFGLPAV AFESPGELLP SKRLHLPFPP G

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.0
Match:	1dt3A
Description:	Triacylglycerol lipase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [372-520]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSYMEGIWH FGHNADPIFM GTCNGASSSC SLVGYAMETA CHTGRVCVYD VVNDKGWSVN  60
   61 MFNHRIHKVI DEVLLGYEQA AKCVEPEPCV DCYNWKFIPS RDWESSSRLI TKTKSHAAPT 120
  121 TTTRTTATTT SSSTCVGRNW LGFCTKYEL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits