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View Structure Prediction Details

Protein: HCM1
Organism: Saccharomyces cerevisiae
Length: 564 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HCM1.

Description E-value Query
Range
Subject
Range
gi|171654, gi|417110 - gi|417110|sp|P25364.2|HCM1_YEAST RecName: Full=Forkhead transcription factor HCM1; AltName: Full=Hig...
530.0 [0..1] [564..1]
gi|109073113 - gi|109073113|ref|XP_001093593.1| PREDICTED: similar to forkhead box O3A [Macaca mulatta]
208.0 [0..2] [446..18]
gi|60654355 - gi|60654355|gb|AAX29868.1| forkhead box O3A [synthetic construct]
207.0 [0..2] [446..18]
gi|149046963, gi... - gi|34852910|ref|XP_215421.2| PREDICTED: similar to forkhead box O3a [Rattus norvegicus], gi|15782273...
206.0 [0..2] [446..18]
FOXO3 - forkhead box O3
gi|61363728 - gi|61363728|gb|AAX42435.1| forkhead box O3A [synthetic construct]
206.0 [0..2] [446..18]
gi|183396873, gi... - gi|183396873|gb|AAI66015.1| Forkhead box O3 [synthetic construct], gi|117616362|gb|ABK42199.1| Fkhr2...
FOXO3_MOUSE - Forkhead box protein O3 OS=Mus musculus GN=Foxo3 PE=1 SV=1
205.0 [0..2] [446..18]
FXC1B_DANRE - Forkhead box C1-B OS=Danio rerio GN=foxc1b PE=2 SV=1
200.0 [0..63] [463..29]
gi|76631009 - gi|76631009|ref|XP_615634.2| PREDICTED: forkhead box O3 [Bos taurus]
196.0 [0..2] [446..18]
FOXO3_XENLA - Forkhead box protein O3 OS=Xenopus laevis GN=foxo3 PE=2 SV=1
193.0 [0..6] [446..20]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMNEDISIID GHNSFLTEKS TVLLTQAKRT LEDEKEMITP PSSTVRKTMK EVNKRPSHPL  60
   61 SPDHSSPIAP SKAKRQRSDT CARSNGNLTL EEILQSLERR RI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [103-204]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGELAKKPPY SYATLICLAI LQSQEGKLTL SQIYHWIHVH FPYYKQKDAS WQNSIRHNLS  60
   61 LNDAFIKTEK SCDGKGHFWE VRPGAETKFF KGENRGYEFV KD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.221849
Match: 1d5vA
Description: Adipocyte-transcription factor FREAC-11 (s12, fkh-14)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [205-436]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLQDIGKYFE IDSTLDELEQ VESGEGNDDL PDEEEREEAG KFPSIEIQLN SSPILRVSQL  60
   61 HHIPQLKTDN SVLNPHENLE SMRNMIENDV NNIDSLEPPY VMKKYHTSLG LPSLVNAKDH 120
  121 FQAGVKNNNI TQANRFNTLP ITSAKSPQNF RKYFTSFNSN FEDLSPLRSN VGAGSLLDPL 180
  181 PYSPLKLYDQ KNLALMSKPQ SQQSYSNSQL PPPPSSHGSD LLKTPKMRHS DG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [437-564]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEKTPSRLIS TPKDGNSILR KWQTPSHLFE DLYCSPLFRA IETPIRYITT PGGTLETQIS  60
   61 PRKSSAPDVL TSATNSKFAS SGLFGVDVYS VWKRATEKIS DGNNTTDSNQ KHHPYHNHPS 120
  121 NDSGNEKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle