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View Structure Prediction Details

Protein: PWP2
Organism: Saccharomyces cerevisiae
Length: 923 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PWP2.

Description E-value Query
Range
Subject
Range
PWP2_YEAST - Periodic tryptophan protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PWP2 PE=1 ...
PWP2 - Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA...
0.0 [1..923] [1..923]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [15..740] [865..1515]
PWP2_NEUCR - Periodic tryptophan protein 2 homolog OS=Neurospora crassa GN=B18D24.40 PE=3 SV=1
PWP2_NEUCR - Periodic tryptophan protein 2 homolog OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708...
0.0 [1..896] [1..897]
PWP2_SCHPO - Periodic tryptophan protein 2 homolog OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC...
SPBC713.04c - U3 snoRNP-associated protein Utp1
0.0 [1..853] [1..846]
PWP2 - PWP2 periodic tryptophan protein homolog (yeast)
0.0 [1..862] [1..888]
FBpp0311844, CG1... - This gene is referred to in FlyBase by the symbol Dmel\CG12325 (CG12325, FBgn0033557). It is a prote...
0.0 [1..897] [1..934]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSDFKFSNL LGTVYRQGNI TFSDDGKQLL SPVGNRVSVF DLINNKSFTF EYEHRKNIAA  60
   61 IDLNKQGTLL ISIDEDGRAI LVNF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [85-416]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KARNVLHHFN FKEKCSAVKF SPDGRLFALA SGRFLQIWKT PDVNKDRQFA PFVRHRVHAG  60
   61 HFQDITSLTW SQDSRFILTT SKDLSAKIWS VDSEEKNLAA TTFNGHRDYV MGAFFSHDQE 120
  121 KIYTVSKDGA VFVWEFTKRP SDDDDNESED DDKQEEVDIS KYSWRITKKH FFYANQAKVK 180
  181 CVTFHPATRL LAVGFTSGEF RLYDLPDFTL IQQLSMGQNP VNTVSVNQTG EWLAFGSSKL 240
  241 GQLLVYEWQS ESYILKQQGH FDSTNSLAYS PDGSRVVTAS EDGKIKVWDI TSGFCLATFE 300
  301 EHTSSVTAVQ FAKRGQVMFS SSLDGTVRAW DL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 131.274545
Match: 1gxrA_
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [417-501]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IRYRNFRTFT GTERIQFNCL AVDPSGEVVC AGSLDNFDIH VWSVQTGQLL DALSGHEGPV  60
   61 SCLSFSQENS VLASASWDKT IRIWS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 252.69897
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [502-676]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFGRSQQVEP IEVYSDVLAL SMRPDGKEVA VSTLKGQISI FNIEDAKQVG NIDCRKDIIS  60
   61 GRFNQDRFTA KNSERSKFFT TIHYSFDGMA IVAGGNNNSI CLYDVPNEVL LKRFIVSRNM 120
  121 ALNGTLEFLN SKKMTEAGSL DLIDDAGENS DLEDRIDNSL PGSQRGGDLS TRKMR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 202.9897
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [677-743]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEVRVTSVQF SPTANAFAAA STEGLLIYST NDTILFDPFD LDVDVTPHST VEALREKQFL  60
   61 NALVMAF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [744-923]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLNEEYLINK VYEAIPIKEI PLVASNIPAI YLPRILKFIG DFAIESQHIE FNLIWIKALL  60
   61 SASGGYINEH KYLFSTAMRS IQRFIVRVAK EVVNTTTDNK YTYRFLVSTD GSMEDGAADD 120
  121 DEVLLKDDAD EDNEENEEND VVMESDDEEG WIGFNGKDNK LPLSNENDSS DEEENEKELP 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle