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View Structure Prediction Details

Protein: BUD5
Organism: Saccharomyces cerevisiae
Length: 642 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BUD5.

Description E-value Query
Range
Subject
Range
BUD5_YEAST - Bud site selection protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BUD5 PE=1 S...
BUD5 - GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; muta...
gi|151943859 - gi|151943859|gb|EDN62159.1| GTP/GDP exchange factor for Rsr1 protein [Saccharomyces cerevisiae YJM78...
0.0 [1..642] [1..642]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [105..642] [1..538]
GNDS_RAT - Ral guanine nucleotide dissociation stimulator OS=Rattus norvegicus GN=Ralgds PE=1 SV=1
0.0 [174..639] [62..628]
gi|119608444, gi... - gi|18676576|dbj|BAB84940.1| FLJ00185 protein [Homo sapiens], gi|119608444|gb|EAW88038.1| ral guanine...
0.0 [174..639] [62..635]
GNDS_MOUSE - Ral guanine nucleotide dissociation stimulator OS=Mus musculus GN=Ralgds PE=1 SV=1
2.0E-99 [174..639] [7..585]

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Predicted Domain #1
Region A:
Residues: [1-150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPKNKYVYI CVEYIYIYFA KIHKQSTLSS DTTKMFVLID NVLAYLLEQD DLFVTARFAI  60
   61 QGQIVSRRVN KIHISNITDV LLQQFISHTL PYNDNIVPKK ILDSMRTAVR QLLEATACVS 120
  121 RECPLVKRSQ DIKRARKRLL SDWYRLGADA 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.714 a.1.1 Globin-like
View Download 0.714 a.1.1 Globin-like
View Download 0.728 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.728 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.629 a.118.8 TPR-like
View Download 0.498 a.74.1 Cyclin-like
View Download 0.584 a.1.1 Globin-like
View Download 0.584 a.1.1 Globin-like
View Download 0.511 a.1.1 Globin-like
View Download 0.511 a.1.1 Globin-like
View Download 0.497 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.493 a.3.1 Cytochrome c
View Download 0.491 a.66.1 Transducin (alpha subunit), insertion domain
View Download 0.486 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.484 a.118.12 Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain
View Download 0.472 a.118.8 TPR-like
View Download 0.472 a.74.1 Cyclin-like
View Download 0.468 a.160.1 Poly(A) polymerase, middle domain
View Download 0.467 a.1.1 Globin-like
View Download 0.458 d.110.4 SNARE-like
View Download 0.444 a.133.1 Phospholipase A2, PLA2
View Download 0.441 a.146.1 Telomeric repeat binding factor (TRF) dimerisation domain
View Download 0.439 c.47.1 Thioredoxin-like
View Download 0.426 a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.420 a.118.9 ENTH/VHS domain
View Download 0.419 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.412 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.407 a.74.1 Cyclin-like
View Download 0.406 d.110.4 SNARE-like
View Download 0.402 a.72.1 Functional domain of the splicing factor Prp18
View Download 0.402 f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.401 a.24.17 Group V grass pollen allergen
View Download 0.399 f.1.2 Diphtheria toxin, middle domain
View Download 0.399 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.399 a.4.5 "Winged helix" DNA-binding domain
View Download 0.388 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.387 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.381 d.58.30 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
View Download 0.377 a.118.9 ENTH/VHS domain
View Download 0.369 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.359 a.26.1 4-helical cytokines
View Download 0.359 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.353 a.96.1 DNA-glycosylase
View Download 0.350 d.164.1 SMAD MH1 domain
View Download 0.348 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.346 c.10.1 RNI-like
View Download 0.334 f.13.1 Family A G protein-coupled receptor-like
View Download 0.333 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.332 c.78.2 Aspartate/glutamate racemase
View Download 0.331 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.328 a.74.1 Cyclin-like
View Download 0.328 a.29.2 Bromodomain
View Download 0.325 f.14.1 Voltage-gated potassium channels
View Download 0.325 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.323 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.318 a.126.1 Serum albumin-like
View Download 0.312 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.311 a.19.1 Fertilization protein
View Download 0.303 a.39.2 Insect pheromon/odorant-binding proteins
View Download 0.294 a.96.1 DNA-glycosylase
View Download 0.292 d.162.1 LDH C-terminal domain-like
View Download 0.287 a.1.2 alpha-helical ferredoxin
View Download 0.285 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.280 a.25.1 Ferritin-like
View Download 0.280 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.278 a.118.1 ARM repeat
View Download 0.277 b.60.1 Lipocalins
View Download 0.275 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.274 a.118.8 TPR-like
View Download 0.271 a.24.15 FAD-dependent thiol oxidase
View Download 0.266 c.10.1 RNI-like
View Download 0.255 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.252 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.247 a.25.1 Ferritin-like
View Download 0.244 a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.243 c.31.1 DHS-like NAD/FAD-binding domain
View Download 0.241 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.235 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.234 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.229 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.229 a.118.1 ARM repeat
View Download 0.224 f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.220 a.11.2 Second domain of FERM
View Download 0.213 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.211 d.211.2 Plakin repeat
View Download 0.211 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.210 f.1.3 delta-Endotoxin (insectocide), N-terminal domain
View Download 0.208 a.47.2 t-snare proteins
View Download 0.207 a.74.1 Cyclin-like
View Download 0.206 a.24.9 alpha-catenin/vinculin
View Download 0.204 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.203 c.66.1 S-adenosyl-L-methionine-dependent methyltransferases

Predicted Domain #2
Region A:
Residues: [151-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMDAVLLVVN SAWRFLAVWR PFVNSIQHAT QELYQNIAHY LLHGNVNIQR VTALIQLVMG  60
   61 QDDLLFSMDD VLQEVFRIQL YLNKMLPHNS HKWQKPSPFD SANLLLNFRD WTTDNALLQE 120
  121 LLLSYPTINK NKHKNHSVPR LIQIWVESYW QDSETTLKDI LNFWYSHLAE YYEYQELFAD 180
  181 IVQLFINKKR TRQLKIHYIG LTDKEIEEN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [560-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFIRDGNDTF TKDGNNVNMQ KFNQITK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 112.0
Match: 1bkdS_
Description: Son of sevenless protein homolog 1 (sos-1)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [360-559]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPPLDYENLF LQYEIDKTNA NDELCGATDL SDLLFQWKQG ELLEVEAFAL NVSPWSLAKT  60
   61 LTLLESSLYL DIETIEFTRH FKHNDTTIDS VFTLSNQLSS YVLETTLQQT HTISYWLQVA 120
  121 LSCLYLRNLN SLASIITSLQ NHSIERLSLP IDVKSDHLFQ RLKVVVHPNN NYNVYRRTIK 180
  181 HIFHSQLPCV PFTSLLIRDI 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [587-642]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVAFAQYLQQ KQYEDIHCSN TTARSLLGAM IKVHTLYNDN KDRAYQVSIA KVPRLT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 112.0
Match: 1bkdS_
Description: Son of sevenless protein homolog 1 (sos-1)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle