YRC Public Data Repository - Protein Structure Prediction

Protein:	FEN1
Organism:	Saccharomyces cerevisiae
Length:	347 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FEN1.

Description	E-value	Query Range	Subject Range
FEN1 - Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons ... gi\|190406467 - gi\|190406467\|gb\|EDV09734.1\| elongation of fatty acids protein 2 [Saccharomyces cerevisiae RM11-1a] ELO2_YEAST - Elongation of fatty acids protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ELO2... gi\|207347293 - gi\|207347293\|gb\|EDZ73515.1\| YCR034Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|151943854 - gi\|151943854\|gb\|EDN62154.1\| fenpropimorph resistance-related protein [Saccharomyces cerevisiae YJM78...	9.0E-96	[1..347]	[1..347]
SPAC1B2.03c - GNS1 /SUR4 family protein ELOH1_SCHPO - Putative elongation of fatty acids protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) ...	9.0E-73	[22..318]	[12..307]
ELOVL5 - ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) ENSPTRT00000033809 - null	2.0E-70	[37..346]	[2..298]
ELOV5_RAT - Elongation of very long chain fatty acids protein 5 OS=Rattus norvegicus GN=Elovl5 PE=1 SV=1	4.0E-70	[37..346]	[2..298]
ELO4_MOUSE, ELOV... - Elongation of very long chain fatty acids protein 4 OS=Mus musculus GN=Elovl4 PE=2 SV=1, (Q9EQC4) El...	3.0E-64	[39..346]	[19..308]
ELOV4_MACMU - Elongation of very long chain fatty acids protein 4 OS=Macaca mulatta GN=ELOVL4 PE=3 SV=1 ELOV4_MACFA - Elongation of very long chain fatty acids protein 4 OS=Macaca fascicularis GN=ELOVL4 PE=2 SV=1	3.0E-61	[40..346]	[20..310]

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Predicted Domain #1

Region A:
Residues: [1-347]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSLVTQYAA PLFERYPQLH DYLPTLERPF FNISLWEHFD DVVTRVTNGR FVPSEFQFIA  60
   61 GELPLSTLPP VLYAITAYYV IIFGGRFLLS KSKPFKLNGL FQLHNLVLTS LSLTLLLLMV 120
  121 EQLVPIIVQH GLYFAICNIG AWTQPLVTLY YMNYIVKFIE FIDTFFLVLK HKKLTFLHTY 180
  181 HHGATALLCY TQLMGTTSIS WVPISLNLGV HVVMYWYYFL AARGIRVWWK EWVTRFQIIQ 240
  241 FVLDIGFIYF AVYQKAVHLY FPILPHCGDC VGSTTATFAG CAIISSYLVL FISFYINVYK 300
  301 RKGTKTSRVV KRAHGGVAAK VNEYVNVDLK NVPTPSPSPK PQHRRKR

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	222.19382
Match:	PF01151
Description:	GNS1/SUR4 family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [143-347]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQPLVTLYYM NYIVKFIEFI DTFFLVLKHK KLTFLHTYHH GATALLCYTQ LMGTTSISWV  60
   61 PISLNLGVHV VMYWYYFLAA RGIRVWWKEW VTRFQIIQFV LDIGFIYFAV YQKAVHLYFP 120
  121 ILPHCGDCVG STTATFAGCA IISSYLVLFI SFYINVYKRK GTKTSRVVKR AHGGVAAKVN 180
  181 EYVNVDLKNV PTPSPSPKPQ HRRKR

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits