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View Structure Prediction Details

Protein: KAR4
Organism: Saccharomyces cerevisiae
Length: 335 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KAR4.

Description E-value Query
Range		 Subject
Range
gi|151943779 - gi|151943779|gb|EDN62079.1| transcription factor [Saccharomyces cerevisiae YJM789]
KAR4_YEAST - Karyogamy protein KAR4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAR4 PE=1 SV=1
KAR4 - Transcription factor required for gene regulation in repsonse to pheromones; also required during me...
gi|190406394 - gi|190406394|gb|EDV09661.1| Karyogamy protein KAR4 [Saccharomyces cerevisiae RM11-1a]
 0.0 [1..335] [1..335]
gi|10954013 - gi|10954013|gb|AAG25704.1| KAR4-like protein [Saccharomyces servazzii]
 0.0 [33..333] [18..318]
gi|125584920, gi... - gi|50919731|ref|XP_470226.1| Unknown protein with similarity to methyltransferases and transcription...
 2.0E-99 [40..333] [444..753]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 9.0E-99 [40..335] [562..874]
gi|10047331 - gi|10047331|dbj|BAB13453.1| KIAA1627 protein [Homo sapiens]
ENSPTRT00000030485 - null
 3.0E-98 [26..326] [109..408]
METL1_ARATH - Methyltransferase-like protein 1 OS=Arabidopsis thaliana GN=EMB1691 PE=2 SV=1
 4.0E-71 [40..245] [562..772]
CG5933-PA - This gene is referred to in FlyBase by the symbol Dmel\CG5933 (CG5933, FBgn0039139). It is a protein...
 1.0E-56 [99..316] [406..588]
MTA70_MOUSE - N6-adenosine-methyltransferase subunit METTL3 OS=Mus musculus GN=Mettl3 PE=1 SV=2
 2.0E-56 [99..316] [388..570]

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Predicted Domain #1
Region A:
Residues: [1-58] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFQDPTYDQ NKSRHINNSH LQGPNQETIE MKSKHVSFKP SRDFHTNDYS NNYIHGKS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [59-335] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPQQHVTNIE NRVDGYPKLQ KLFQAKAKQI NQFATTPFGC KIGIDSIVPT LNHWIQNENL  60
   61 TFDVVMIGCL TENQFIYPIL TQLPLDRLIS KPGFLFIWAN SQKINELTKL LNNEIWAKKF 120
  121 RRSEELVFVP IDKKSPFYPG LDQDDETLME KMQWHCWMCI TGTVRRSTDG HLIHCNVDTD 180
  181 LSIETKDTTN GAVPSHLYRI AENFSTATRR LHIIPARTGY ETPVKVRPGW VIVSPDVMLD 240
  241 NFSPKRYKEE IANLGSNIPL KNEIELLRPR SPVQKAQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle