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View Structure Prediction Details

Protein: PPS1
Organism: Saccharomyces cerevisiae
Length: 807 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PPS1.

Description E-value Query
Range
Subject
Range
PPS1_YEAST - Dual specificity protein phosphatase PPS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
PPS1 - Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the...
0.0 [1..807] [1..807]
gi|85081406 - gi|85081406|ref|XP_956712.1| hypothetical protein NCU03426 [Neurospora crassa OR74A]
gi|32404142, gi|... - gi|32404142|ref|XP_322684.1| hypothetical protein [Neurospora crassa], gi|28917787|gb|EAA27476.1| co...
2.0E-76 [406..788] [334..666]
DUS1B_XENLA - Dual specificity protein phosphatase 1-B OS=Xenopus laevis GN=dusp1-b PE=2 SV=1
2.0E-51 [488..785] [80..318]
DUS4_RAT - Dual specificity protein phosphatase 4 OS=Rattus norvegicus GN=Dusp4 PE=2 SV=1
2.0E-51 [488..785] [102..339]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-51 [488..785] [101..338]
gi|1255785 - gi|1255785|gb|AAC50452.1| MKP-2
5.0E-51 [488..785] [101..338]
DUS4_CHICK - Dual specificity protein phosphatase 4 OS=Gallus gallus GN=DUSP4 PE=2 SV=1
4.0E-49 [488..785] [85..319]

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Predicted Domain #1
Region A:
Residues: [1-446]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLEVPSITP GELHDLMRLH QDAEWPECKK MFPWAHDISF GQPPDFPHSL AIVKSQSDAN  60
   61 NSALLRNSLE VNDIFQSWKV RTSFHREGDT CETGNDSNGF QYPNNTKELL NLLKFQIRQL 120
  121 ELQVDDVALE NAATYCHNHS ILPFLKVDPR GLSLELKRYS RNKVGSNTTL KRSGQDVWGR 180
  181 RGLFRRFDLQ CAKMIEMVDN IVIYCSRTGG STDMQTESAP ACSHEGNCPN CTTLALLLQI 240
  241 CLMFVQKGYV GSGGSLYKTN LFICTYQNFN TDIPQTLIGT PLLDNEFFKN NTPLNLCSSP 300
  301 SEIVCFNNVD KNMVLCEKLE LNKLTSATRL EETGLICGNT TDWHNYQIIK KNNISLTHRF 360
  361 EENTSIVNLK SLNYDTDNPT TSISQLYNIP NTKEVWKLII KCTSNSQMPS LTKIRTYLDL 420
  421 LLDDDASKSQ EHLHLTFPAS GSIGLG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [447-583]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLNIQSVEIL LNVCYLIFQV SQVQELLTFM YCEDGYTETS LLLTAYIIFH FNIPLQDALL  60
   61 RIHPRPFFLF PSDLQILGHL QPVLREFSPQ NGSNLKLYAN ALKFRDKSFQ LHISSELFSS 120
  121 IFFMKIPLES NFVNLKG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.881 0.191 protein tyrosine/threonine phosphatase activity a.118.8 TPR-like
View Download 0.538 0.142 protein tyrosine/threonine phosphatase activity d.211.1 Ankyrin repeat
View Download 0.538 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.531 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.497 N/A N/A a.79.1 Antitermination factor NusB
View Download 0.484 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.476 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.472 N/A N/A a.74.1 Cyclin-like
View Download 0.459 N/A N/A a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.455 N/A N/A b.60.1 Lipocalins
View Download 0.448 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.448 N/A N/A c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.439 N/A N/A a.96.1 DNA-glycosylase
View Download 0.413 N/A N/A a.1.1 Globin-like
View Download 0.408 N/A N/A a.118.8 TPR-like
View Download 0.388 N/A N/A a.25.1 Ferritin-like
View Download 0.378 N/A N/A c.114.1 YchN-like
View Download 0.371 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.364 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.356 N/A N/A a.168.1 GEF domain of SopE toxin
View Download 0.356 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.350 N/A N/A a.97.1 An anticodon-binding domain of class I aminoacyl-tRNA synthetases
View Download 0.345 N/A N/A d.113.1 Nudix
View Download 0.338 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.336 N/A N/A a.71.2 Helical domain of Sec23/24
View Download 0.333 N/A N/A a.74.1 Cyclin-like
View Download 0.318 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.311 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.310 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.309 N/A N/A a.118.1 ARM repeat
View Download 0.309 N/A N/A a.118.1 ARM repeat
View Download 0.305 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.302 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.296 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.285 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.282 N/A N/A g.53.1 TAZ domain
View Download 0.281 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.279 N/A N/A a.25.1 Ferritin-like
View Download 0.275 N/A N/A a.25.1 Ferritin-like
View Download 0.269 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.267 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.262 N/A N/A c.23.1 CheY-like
View Download 0.258 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.257 N/A N/A d.131.1 DNA clamp
View Download 0.254 N/A N/A c.55.2 Creatinase/prolidase N-terminal domain
View Download 0.253 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.247 N/A N/A d.211.1 Ankyrin repeat
View Download 0.244 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.241 N/A N/A a.95.1 Influenza virus matrix protein M1
View Download 0.239 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.238 N/A N/A f.1.1 Colicin
View Download 0.230 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.227 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.217 N/A N/A a.126.1 Serum albumin-like
View Download 0.212 N/A N/A d.8.1 Urease, gamma-subunit
View Download 0.209 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like

Predicted Domain #3
Region A:
Residues: [584-807]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLPSRILRHL YLGSLDHAQN PALLKSLGIT HIVSVGEVVS WTLNKDKIAH PVRPHRAITM  60
   61 TNTNEVAGNT TCNKSRNRAD TVVSDKQENG SNVVISENSG FQICQIENLD DNGKDPLFHQ 120
  121 IDKVLDFISN SEATGGKVLV HCMVGVSRSA TVCIAECMRY LQCDLASAYL FVRVRRLNVI 180
  181 IQPNLFFVYE LFKWWKKHYN REKDKTMDWH IICRGIAEVN MKYT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 102.124002
Match: 1ikzA_
Description: Mapk phosphatase

Predicted Domain #4
Region A:
Residues: [379-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTTSISQLYN IPNTKEVWKL IIKCTSNSQM PSLTKIRTYL DLLLDDDASK SQEHLHLTFP  60
   61 ASGSIGLGNL NIQSVEILLN VCYLIFQVSQ VQELLTFMYC EDGYTETSLL LTAYIIFHFN 120
  121 IPLQDALLRI HPRPFFLFPS DLQILGHLQP VLREFSPQNG SNLKLYANAL KFRDKSFQLH 180
  181 ISSELFSSIF FMKIPLESNF VNLKGPLPSR ILRHLYLGSL DHAQNPALLK S

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.18
Match: 2hxpA
Description: No description for 2hxpA was found.

Predicted Domain #5
Region A:
Residues: [610-807]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGITHIVSVG EVVSWTLNKD KIAHPVRPHR AITMTNTNEV AGNTTCNKSR NRADTVVSDK  60
   61 QENGSNVVIS ENSGFQICQI ENLDDNGKDP LFHQIDKVLD FISNSEATGG KVLVHCMVGV 120
  121 SRSATVCIAE CMRYLQCDLA SAYLFVRVRR LNVIIQPNLF FVYELFKWWK KHYNREKDKT 180
  181 MDWHIICRGI AEVNMKYT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.522879
Match: 2esbA
Description: No description for 2esbA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle