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View Structure Prediction Details

Protein: YBR271W
Organism: Saccharomyces cerevisiae
Length: 419 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBR271W.

Description E-value Query
Range
Subject
Range
YBR271W - Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green flu...
EFM2_YEAST - Protein-lysine N-methyltransferase EFM2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
0.0 [1..419] [1..419]
gi|14585877, gi|... - gi|42475946|ref|NP_963892.1| hypothetical protein LOC196483 isoform 2 [Homo sapiens], gi|14585877|gb...
1.0E-48 [126..401] [6..279]
SPAC3A11.03 - methyltransferase
YEZ3_SCHPO - Uncharacterized protein C3A11.03 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC3A11....
4.0E-33 [100..343] [28..243]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-32 [101..343] [1..215]
ANM11_ARATH - Protein arginine N-methyltransferase 1.1 OS=Arabidopsis thaliana GN=PRMT11 PE=1 SV=1
6.0E-31 [230..419] [84..267]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDPLDLYTP DDIQVEALQF NLAEREPKDP CSPQRDEILT AVDEEESDDD DTIIDNLDLP  60
   61 SVKYAPPEVI LCILILLKPD RQVNFNQET

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.627 a.39.1 EF-hand
View Download 0.635 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.556 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.642 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.427 a.3.1 Cytochrome c
View Download 0.413 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.410 a.61.1 Retroviral matrix proteins
View Download 0.361 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.328 a.85.1 Hemocyanin, N-terminal domain
View Download 0.318 a.77.1 DEATH domain
View Download 0.317 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.295 a.39.1 EF-hand
View Download 0.282 a.74.1 Cyclin-like
View Download 0.247 a.39.2 Insect pheromon/odorant-binding proteins
View Download 0.242 a.3.1 Cytochrome c
View Download 0.238 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.221 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.218 a.11.2 Second domain of FERM
View Download 0.206 a.28.1 ACP-like
View Download 0.204 a.158.1 F-box domain

Predicted Domain #2
Region A:
Residues: [90-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKNKSVLEVC KSHGLEPDLL KRLLTWYTEE WPNKRLNSLE KICNKIPMLR FTVSKELLLG  60
   61 YYTSVLKKYN NSCGLNEEII QELLKELSSR ISENCGRTAQ PSI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.699 0.116 S-adenosylmethionine-dependent methyltransferase activity a.39.1 EF-hand
View Download 0.681 0.025 cytoplasm a.118.8 TPR-like
View Download 0.683 0.011 S-adenosylmethionine-dependent methyltransferase activity a.74.1 Cyclin-like
View Download 0.747 0.008 S-adenosylmethionine-dependent methyltransferase activity a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.636 N/A N/A a.74.1 Cyclin-like
View Download 0.441 N/A N/A a.98.1 R1 subunit of ribonucleotide reductase, N-terminal domain
View Download 0.441 N/A N/A a.130.1 Chorismate mutase II
View Download 0.425 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.379 N/A N/A d.56.1 GroEL-intermediate domain like
View Download 0.378 N/A N/A a.84.1 Scaffolding protein gpD of bacteriophage procapsid
View Download 0.376 N/A N/A a.141.1 Frizzled cystein-rich domain
View Download 0.333 N/A N/A c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.329 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.328 N/A N/A a.54.1 Domain of early E2A DNA-binding protein, ADDBP
View Download 0.319 N/A N/A d.192.1 YlxR-like
View Download 0.318 N/A N/A a.4.3 ARID-like
View Download 0.312 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.301 N/A N/A a.3.1 Cytochrome c
View Download 0.300 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.289 N/A N/A a.61.1 Retroviral matrix proteins
View Download 0.287 N/A N/A d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.287 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.281 N/A N/A a.3.1 Cytochrome c
View Download 0.274 N/A N/A a.60.11 Hypothetical protein YjbJ
View Download 0.270 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.270 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.268 N/A N/A a.39.1 EF-hand
View Download 0.262 N/A N/A a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.259 N/A N/A d.2.1 Lysozyme-like
View Download 0.258 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.254 N/A N/A a.5.3 N-terminal domain of phosphatidylinositol transfer protein sec14p
View Download 0.251 N/A N/A a.135.1 Tetraspanin
View Download 0.245 N/A N/A a.24.17 Group V grass pollen allergen
View Download 0.245 N/A N/A c.78.2 Aspartate/glutamate racemase
View Download 0.244 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.242 N/A N/A c.3.1 FAD/NAD(P)-binding domain
View Download 0.237 N/A N/A a.28.1 ACP-like
View Download 0.232 N/A N/A a.7.6 Ribosomal protein S20
View Download 0.230 N/A N/A a.1.1 Globin-like
View Download 0.228 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.226 N/A N/A d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.225 N/A N/A a.3.1 Cytochrome c
View Download 0.216 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.214 N/A N/A a.118.1 ARM repeat
View Download 0.213 N/A N/A a.21.1 HMG-box
View Download 0.211 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.211 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.211 N/A N/A a.60.12 DNA polymerase beta-like, second domain
View Download 0.210 N/A N/A a.4.1 Homeodomain-like
View Download 0.208 N/A N/A a.39.1 EF-hand
View Download 0.208 N/A N/A b.40.1 Staphylococcal nuclease
View Download 0.206 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.205 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.203 N/A N/A a.149.1 RNase III endonuclease catalytic domain
View Download 0.201 N/A N/A a.4.5 "Winged helix" DNA-binding domain

Predicted functions:

Term Confidence Notes
transferase activity 0.569065423404044 bayes_pls_golite062009
catalytic activity 0.486907672100804 bayes_pls_golite062009
methyltransferase activity 0.155495931533276 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.145822362574272 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [193-419]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VRYFELRNLS TSIPLHEPSL TADNLGWKTW GSSLILSQLV VDHLDYLHTT NVNMLANSDI  60
   61 KQIKVLELGA GTGLVGLSWA LKWKELYGTE NIEIFVTDLP EIVTNLKKNV SLNNLGDFVQ 120
  121 AEILDWTNPH DFIDKFGHEN EFDVILIADP IYSPQHPEWV VNMISKFLAA SGTCHLEIPL 180
  181 RAKYAKEREV LKLLLKESDL KVVEERHSEG VDDWGAVKYL YRQIVRN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.39794
Match: 1f3lA_
Description: Arginine methyltransferase, HMT1
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle