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View Structure Prediction Details

Protein: MTC4
Organism: Saccharomyces cerevisiae
Length: 694 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTC4.

Description E-value Query
Range
Subject
Range
MTC4 - Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent prot...
MTC4_YEAST - Maintenance of telomere capping protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
0.0 [1..694] [1..694]
gi|25496719 - pir||B97033 uncharacterized protein, related to enterotoxins of other Clostridiales [imported] - Clo...
gi|15894364, gi|... - gi|15894364|ref|NP_347713.1| hypothetical protein CAC1079 [Clostridium acetobutylicum ATCC 824], gi|...
0.001 [234..430] [65..244]

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Predicted Domain #1
Region A:
Residues: [1-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTHTNEHDHK AEQQQNGRGD TTTETVNPQK MKLVTKLLID NKFGLMDDLN FSIPLTASSE  60
   61 GVPISAKTSE LGTEYLKNQQ ENSVSPILPI SRSTRIKADR VRIYLDYYYN ILERCISIDS 120
  121 SQNHHEGVEG VYNPLQVIRN RKLKKKHHEL PTREFYTTKH PIIAIKQFSK KPNKKMPWFV 180
  181 DINEKYMDLT WRTSHWEELV DPQGKLWFQS YSPSNESSGS SSSRRHHGHH IHPRRHLQHH 240
  241 SRVRTANSVH SNTQSLTPKR VMTNEEDNNN HNNNNMITKI ATTPEAQISR NKKSDLNLSH 300
  301 IHLEVPITNT VTNTSSDQGS LIIEAKGSSY G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [332-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDRRGSSNTS GSGGKRNSKH YRSKSAGPPE NEKSRMNGLE KIISKTSKGW SRSPKKNTPG  60
   61 LEKQVLLNPT ISNGGTSRRS SNNGESISTN SSKSSMGITF GNTETYKTPV DNGKDAIIRQ 120
  121 SLLSEVPVHT LRGKTSNRSL RAEGEQALES DKELPNGAGS IYEGAPREKT TSQGSEPVGL 180
  181 VSDSLQVDEQ LQRYWHDTRY IMSTVAMMQH RRETHDIVKR REIARRNEIE ITQDADTNIR 240
  241 KTADALTQYD NELNKVLKLG NDWTSKLLND YSIRVETLIS 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.85
Match: 1l2qA
Description: Monomethylamine methyltransferase MtmB
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [612-694]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSDRILSDIN TTLTLKLKMF QENTERYVTV KVMRAQKMTK TIYRLLEFGI VLVLWTIWFL  60
   61 FSVLRSIRFT IFLVLKIIKA LLW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [436-501]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TYKTPVDNGK DAIIRQSLLS EVPVHTLRGK TSNRSLRAEG EQALESDKEL PNGAGSIYEG  60
   61 APREKT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [502-694]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSQGSEPVGL VSDSLQVDEQ LQRYWHDTRY IMSTVAMMQH RRETHDIVKR REIARRNEIE  60
   61 ITQDADTNIR KTADALTQYD NELNKVLKLG NDWTSKLLND YSIRVETLIS SSDRILSDIN 120
  121 TTLTLKLKMF QENTERYVTV KVMRAQKMTK TIYRLLEFGI VLVLWTIWFL FSVLRSIRFT 180
  181 IFLVLKIIKA LLW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle