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View Structure Prediction Details

Protein: YBP1
Organism: Saccharomyces cerevisiae
Length: 674 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBP1.

Description E-value Query
Range
Subject
Range
YBP1_YEAST - YAP1-binding protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YBP1 PE=1 SV=1
YBP1 - Protein required for oxidation of specific cysteine residues of the transcription factor Yap1p, resu...
0.0 [1..674] [1..674]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPIDDILFE VTDAFKTQKE DLLELVTLID IYGEQVNQEG SYEEKTRFIE TLNTLLEDNP  60
   61 STTGEIGWDL PKGLLKFLSK D

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [555-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLIVEKLSKL K

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.98
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [82-130]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVDVNGRLGT NMIVQGVMKC FYAISIQGEP KKCLITGLEL LSSLCSKDF

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.98
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [131-327]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKSDQQNKED FVDKKANTLP PEGVIENSSN RKDFPSYGES KSSNEFFLKL KSYILFEFIG  60
   61 ASLKRISTLF PSKYLGAAVS TIEKFVYSHA DTFEDALFLL RRVYTFCRNY IPPDPPKDIQ 120
  121 LNEDFTREMF DKVVEEESEL QVRLLRRLCT FGISTPIKTV TTNADVKYYC ALNQQKFELS 180
  181 AYYTEYLELF CRYYQMA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [380-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQKAAKEKNV GLDYNGVILF SGIHYLETNQ HLVKEMNITD AIYLYLRFTT PSLYSKVYYN  60
   61 VAVESVSRYW LWYAITTEPL EDVKKELKNL SVFVTKTLLH VLLQKNCIQV NQQLRMITFT 120
  121 LLTRLLCLIP EKVAFEFILD VLKTSPLPLA KTSVLCVFKD LSRRRISTKD NDSET

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [566-674]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNDSNKAQQS NIRHYIQLDS SKMKAVHDCC LQTIQDSFTA DAKKSDILLL LTYLNIFIVL  60
   61 KKTWDEDLLK IVCSKIDSNL KSVEPDKLPK YKEIVDKNES LNDYFTGIK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.98
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [328-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSLDVDIEGE FQNVIKECRI IYKSVPQEIS AVNDEAKLVL ERMVYKLAYT FE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.98
Match: 1bgxT
Description: 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [569-674]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNKAQQSNIR HYIQLDSSKM KAVHDCCLQT IQDSFTADAK KSDILLLLTY LNIFIVLKKT  60
   61 WDEDLLKIVC SKIDSNLKSV EPDKLPKYKE IVDKNESLND YFTGIK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.875 a.74.1 Cyclin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle