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View Structure Prediction Details

Protein: EHT1
Organism: Saccharomyces cerevisiae
Length: 451 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EHT1.

Description E-value Query
Range
Subject
Range
gi|4586632 - gi|4586632|dbj|BAA76441.1| alcohol acyl transferase [Saccharomyces cerevisiae]
0.0 [1..451] [1..451]
gi|15240586, gi|... - gi|8777426|dbj|BAA97016.1| unnamed protein product [Arabidopsis thaliana], gi|15240586|ref|NP_199806...
4.0E-54 [17..447] [42..410]
ABHD3_MOUSE - Phospholipase ABHD3 OS=Mus musculus GN=Abhd3 PE=1 SV=1
4.0E-52 [44..448] [65..403]
gi|18203711 - gi|18203711|gb|AAH21196.1| Abhydrolase domain containing 3 [Homo sapiens]
5.0E-50 [44..448] [65..403]

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Predicted Domain #1
Region A:
Residues: [1-109]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEVSKWPAI NPFHWGYNGT VSHIVGENGS IKLHLKDNKE QVDFDEFANK YVPTLKNGAQ  60
   61 FKLSPYLFTG ILQTLYLGAA DFSKKFPVFY GREIVKFSDG GVCTADWLI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [110-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSWKKDYEFD QSTTSFDKKK FDKDEKATHP EGWPRLQPRT RYLKDNELEE LREVDLPLVV  60
   61 ILHGLAGGSH EPIIRSLAEN LSRSGRFQVV VLNTRGCARS KITTRNLFTA YHTMDIREFL 120
  121 QREKQRHPDR KLYAVGCSFG ATMLANYLGE EGDKSPLSAA ATLCNPWDLL LSAIRMSQDW 180
  181 WSRTLFSKNI AQFLTRTVQV NMGELGVPNG SLPDHPPTVK NPSFYMFTPE NLIKAKSFKS 240
  241 TREFDEVYTA PALGFPNAME YYKAASSINR VDTIRVPTLV INSRDDPVVG PDQPYSIVEK 300
  301 NPRILYCRTD LGGHLAYLDK DNNSWATKAI AEFFTKFDEL VV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.522879
Match: 1cqzA_
Description: Epoxide hydrolase, N-terminal domain; Mammalian epoxide hydrolase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.39629727416851 bayes_pls_golite062009
lipase activity 0.849473630399459 bayes_pls_golite062009
carboxylesterase activity 0.424330502936163 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.264183693934251 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle