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View Structure Prediction Details

Protein: SMY2
Organism: Saccharomyces cerevisiae
Length: 790 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMY2.

Description E-value Query
Range
Subject
Range
MYH2_PIG - Myosin-2 OS=Sus scrofa GN=MYH2 PE=2 SV=1
gi|55741490 - ref|NP_999301.1| myosin heavy chain 2a [Sus scrofa]
5.0E-66 [41..789] [1038..1791]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
7.0E-66 [29..789] [991..1791]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
9.0E-66 [29..789] [990..1790]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-65 [41..787] [35..786]
gi|6683485 - gi|6683485|dbj|BAA89233.1| skeletal myosin heavy chain [Gallus gallus]
1.0E-65 [41..787] [1038..1789]

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Predicted Domain #1
Region A:
Residues: [1-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLLELFTIL QIPTHAVQWS LRVHHFHSYS LSFYLPSSSP IYSTSQPTSI MIAPDSQRLF  60
   61 GSFDEQFKDL KLDSVDTENN NTHGVSTILD SSPASVNNNT NGAVAASVNT VPGSTFRSNT 120
  121 PLLGGRHPLS RTSSLIDSIG IQRAASPFSS MKEPFIPQSS GVMSSSFWHG DHPESRVSTP 180
  181 VQQHPLLQRN ESSSSFSYAA NLGVNLST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [209-550]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSLAVDITPL STPTAAQSHV NLFPSSDIPP NMSMNGMSQL PAPVSVESSW RYIDTQGQIH  60
   61 GPFTTQMMSQ WYIGGYFAST LQISRLGSTP ETLGINDIFI TLGELMTKLE KYDTDPFTTF 120
  121 DKLHVQTTSS DSINLNLAPY ASGVAATGTI KATENDIFKP LTHDNIWDMD GGTTSKGVDI 180
  181 KLASATTISQ TDESHKQEYK STTMLEKGKK EKSESVAKAL LDEQEKRNRE LKRKEEARLS 240
  241 KKQKQKEDDL LKKQKEQKEQ KEKEALEAEK QKKSEKTKKD TQTQTEGFKT SKDLPSLNSS 300
  301 SANPAPWASK VKVNNAIETS IKNGVSSTGK KKGEPLGLQQ RN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [551-790]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKEEKQKEEL KSVLNWANKS SLPSNQTIDI KSQFQKSPKG MKESSPLKEL EDPNFIEEQK  60
   61 KLWEKVQSSS KQVKSTSSAS TTTSSWTTVT SKGKAPIGTV VSPYSKTNTS LNSSLTAKTS 120
  121 TTSTTTTFAS MNNVSPRQEF IKWCKSQMKL NSGITNNNVL ELLLSLPTGP ESKELIQETI 180
  181 YANSDVMDGR RFATEFIKRR VACEKQGDDP LSWNEALALS GNDDDGWEFQ VVSKKKGRKH 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle