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View Structure Prediction Details

Protein: POL30
Organism: Saccharomyces cerevisiae
Length: 258 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POL30.

Description E-value Query
Range
Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
9.0E-99 [1..258] [1..259]
PCNA_MOUSE - Proliferating cell nuclear antigen OS=Mus musculus GN=Pcna PE=1 SV=2
1.0E-98 [1..258] [1..259]
PCNA_CHICK - Proliferating cell nuclear antigen OS=Gallus gallus GN=PCNA PE=1 SV=1
2.0E-98 [1..258] [1..259]
PCNA_RAT - Proliferating cell nuclear antigen OS=Rattus norvegicus GN=Pcna PE=1 SV=1
5.0E-98 [1..258] [1..259]
PCNA_COTJA - Proliferating cell nuclear antigen OS=Coturnix coturnix japonica GN=PCNA PE=2 SV=1
6.0E-98 [1..258] [1..259]
PCNA_CRIGR - Proliferating cell nuclear antigen OS=Cricetulus griseus GN=PCNA PE=1 SV=1
8.0E-98 [1..258] [1..259]
gi|55651058, gi|... - gi|55651058|ref|XP_514499.1| PREDICTED: proliferating cell nuclear antigen isoform 2 [Pan troglodyte...
PCNA_MACFA - Proliferating cell nuclear antigen OS=Macaca fascicularis GN=PCNA PE=2 SV=1
gi|109092793, gi... - gi|109092795|ref|XP_001115756.1| PREDICTED: proliferating cell nuclear antigen isoform 2 [Macaca mul...
ENSCJAT00000041839 - null
gi|208967140, gi... - gi|61359492|gb|AAX41726.1| proliferating cell nuclear antigen [synthetic construct], gi|61358193|gb|...
PCNA - proliferating cell nuclear antigen
HGNC:8729|MIM:17... - cell nuclear antigen
8.0E-98 [1..258] [1..259]
gi|7248369, gi|7... - gi|7248369|dbj|BAA92702.1| proliferating cell nuclear antigen subtype3 [Xenopus laevis], gi|7248367|...
1.0E-95 [1..258] [1..259]

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Predicted Domain #1
Region A:
Residues: [1-127]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLEAKFEEAS LFKRIIDGFK DCVQLVNFQC KEDGIIAQAV DDSRVLLVSL EIGVEAFQEY  60
   61 RCDHPVTLGM DLTSLSKILR CGNNTDTLTL IADNTPDSII LLFEDTKKDR IAEYSLKLMD 120
  121 IDADFLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1391.09691
Match: 1plq__
Description: Prolifirating cell nuclear antigen (PCNA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA polymerase processivity factor activity 9.9878881203193 bayes_pls_golite062009
DNA-directed DNA polymerase activity 5.01426276108174 bayes_pls_golite062009
DNA polymerase activity 4.9656505576274 bayes_pls_golite062009
nucleotidyltransferase activity 3.23598180825386 bayes_pls_golite062009
mismatched DNA binding 2.75713709757781 bayes_pls_golite062009
DNA insertion or deletion binding 2.48680473192192 bayes_pls_golite062009
nucleic acid binding 2.32553487472442 bayes_pls_golite062009
DNA binding 2.24518789437215 bayes_pls_golite062009
binding 1.88302251910664 bayes_pls_golite062009
dinucleotide insertion or deletion binding 1.68153838099672 bayes_pls_golite062009
mismatch repair complex binding 1.6296761041903 bayes_pls_golite062009
MutLalpha complex binding 1.21442872292245 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.14392061238362 bayes_pls_golite062009
structure-specific DNA binding 0.785542777582287 bayes_pls_golite062009
catalytic activity 0.48077242755678 bayes_pls_golite062009
double-stranded DNA binding 0.457118392479642 bayes_pls_golite062009
protein binding 0.452894757163315 bayes_pls_golite062009
purine-specific mismatch base pair DNA N-glycosylase activity 0.408841404605319 bayes_pls_golite062009
mismatch base pair DNA N-glycosylase activity 0.387975438046246 bayes_pls_golite062009
transferase activity 0.345371754708312 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [128-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IEELQYDSTL SLPSSEFSKI VRDLSQLSDS INIMITKETI KFVADGDIGS GSVIIKPFVD  60
   61 MEHPETSIKL EMDQPVDLTF GAKYLLDIIK GSSLSDRVGI RLSSEAPALF QFDLKSGFLQ 120
  121 FFLAPKFNDE E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1391.09691
Match: 1plq__
Description: Prolifirating cell nuclear antigen (PCNA)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle