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View Structure Prediction Details

Protein: CHS2
Organism: Saccharomyces cerevisiae
Length: 963 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CHS2.

Description E-value Query
Range
Subject
Range
gi|190408795 - gi|190408795|gb|EDV12060.1| chitin synthase 2 [Saccharomyces cerevisiae RM11-1a]
gi|151946429 - gi|151946429|gb|EDN64651.1| chitin synthase [Saccharomyces cerevisiae YJM789]
CHS2 - Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of ...
gi|207347764 - gi|207347764|gb|EDZ73838.1| YBR038Wp-like protein [Saccharomyces cerevisiae AWRI1631]
CHS2_YEAST - Chitin synthase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CHS2 PE=1 SV=1
0.0 [1..963] [1..963]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [60..961] [2..943]
gi|83774827, gi|... - gi|83774827|dbj|BAE64950.1| unnamed protein product [Aspergillus oryzae], gi|19071965|dbj|BAB85684.1...
gi|169783242 - gi|169783242|ref|XP_001826083.1| hypothetical protein [Aspergillus oryzae RIB40]
0.0 [60..933] [2..918]
gi|9082308 - gi|9082308|gb|AAF82801.1|AF276826_1 class I chitin synthase [Coccidioides posadasii]
0.0 [60..933] [2..912]
CHS3_NEUCR - Chitin synthase 3 OS=Neurospora crassa GN=chs-3 PE=3 SV=2
CHS3_NEUCR - Chitin synthase 3 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGS...
0.0 [54..933] [3..886]
CHS2_EXODE - Chitin synthase 2 OS=Exophiala dermatitidis GN=CHS2 PE=3 SV=2
0.0 [11..933] [5..919]
gi|19068022 - gi|19068022|gb|AAL23717.1| chitin synthase A [Glomerella graminicola]
0.0 [25..933] [3..897]
gi|111057805 - gi|111057805|gb|EAT78925.1| hypothetical protein SNOG_13478 [Phaeosphaeria nodorum SN15]
gi|4689032 - gi|4689032|emb|CAB41508.1| putative chitin synthase [Phaeosphaeria nodorum]
0.0 [39..943] [4..904]

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Predicted Domain #1
Region A:
Residues: [1-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRNPFMVEP SNGSPNRRGA SNLSKFYANA NSNSRWANPS EESLEDSYDQ SNVFQGLPAS  60
   61 PSRAALRYSP DRRHRTQFYR DSAHNSPVAP NRYAANLQES PKRAGEAVIH LSEGSNLYPR 120
  121 DNADLPVDPY HLSPQQQPSN NLFGSGRLYS QSSKYTMSTT STTAPSLAEA DDEKEKYLTS 180
  181 TTSY

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.82
Match: 1deqA
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [185-286]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDQSTIFSAD TFNETKFELN HPTRQQYVRR ANSESKRRMV SDLPPPSKKK ALLKLDNPIP  60
   61 KGLLDTLPRR NSPEFTEMRY TACTVEPDDF LREGYTLRFA EM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.344 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain

Predicted Domain #3
Region A:
Residues: [287-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRECQIAICI TMYNEDKYSL ARTIHSIMKN VAHLCKREKS HVWGPNGWKK VSVILISDGR  60
   61 AKVNQGSLDY LAALGVYQED MAKASVNGDP VKAHIFELTT QVSINADLDY VSKDIVPVQL 120
  121 VFCLKEENKK KINSHRWLFN AFCPVLQPTV VTLVDVGTRL NNTAIYRLWK VFDMDSNVAG 180
  181 AAGQIKTMKG KWGLKLFNPL VASQNFEYKI SNILDKPLES VFGYISVLPG ALSAYRYRAL 240
  241 K

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [578-603]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLKYVKEATG ETDVPEDVSE FISQRR

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.34
Match: 1h7lA
Description: Spore coat polysaccharide biosynthesis protein SpsA
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [528-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NHEDGTGPLR SYFLGETQEG RDHDVFTANM YLAEDRILCW ELVAKRDAKW 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [604-627]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RWLNGAMFAA IYAQLHFYQI WKTK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.34
Match: 1h7lA
Description: Spore coat polysaccharide biosynthesis protein SpsA
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [628-747]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSVVRKFFLH VEFLYQFIQM LFSWFSIANF VLTFYYLAGS MNLVIKHGEA LFIFFKYLIF  60
   61 CDLASLFIIS MGNRPQGAKH LFITSMVILS ICATYSLICG FVFAFKSLAS GTESHKIFVD 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.799 0.059 cellular bud neck contractile ring f.14.1 Voltage-gated potassium channels
View Download 0.658 0.048 cellular bud neck contractile ring a.7.1 Spectrin repeat
View Download 0.768 0.048 cellular bud neck contractile ring a.47.2 t-snare proteins
View Download 0.772 0.032 cellular bud neck contractile ring a.2.7 tRNA-binding arm
View Download 0.654 0.007 cellular bud neck contractile ring f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.645 N/A N/A a.7.1 Spectrin repeat
View Download 0.631 N/A N/A a.7.1 Spectrin repeat
View Download 0.593 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.592 N/A N/A a.2.7 tRNA-binding arm
View Download 0.583 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.582 N/A N/A a.7.1 Spectrin repeat
View Download 0.556 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.545 N/A N/A a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.528 N/A N/A a.7.1 Spectrin repeat
View Download 0.514 N/A N/A a.26.1 4-helical cytokines
View Download 0.513 N/A N/A a.47.2 t-snare proteins
View Download 0.498 N/A N/A a.25.1 Ferritin-like
View Download 0.497 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.491 N/A N/A a.29.2 Bromodomain
View Download 0.488 N/A N/A a.47.2 t-snare proteins
View Download 0.474 N/A N/A a.2.7 tRNA-binding arm
View Download 0.474 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.471 N/A N/A a.24.1 Apolipoprotein
View Download 0.470 N/A N/A a.29.2 Bromodomain
View Download 0.469 N/A N/A a.63.1 Apolipophorin-III
View Download 0.462 N/A N/A a.47.2 t-snare proteins
View Download 0.461 N/A N/A a.2.7 tRNA-binding arm
View Download 0.456 N/A N/A a.25.1 Ferritin-like
View Download 0.442 N/A N/A a.24.5 TMV-like viral coat proteins
View Download 0.428 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.419 N/A N/A d.19.1 MHC antigen-recognition domain
View Download 0.419 N/A N/A a.7.1 Spectrin repeat
View Download 0.417 N/A N/A a.2.7 tRNA-binding arm
View Download 0.415 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.410 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.402 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.401 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.400 N/A N/A a.24.1 Apolipoprotein
View Download 0.400 N/A N/A a.24.1 Apolipoprotein
View Download 0.395 N/A N/A a.90.1 Transcription factor STAT-4 N-domain
View Download 0.392 N/A N/A a.26.1 4-helical cytokines
View Download 0.372 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.367 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.365 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.361 N/A N/A a.7.1 Spectrin repeat
View Download 0.360 N/A N/A a.47.2 t-snare proteins
View Download 0.359 N/A N/A a.24.1 Apolipoprotein
View Download 0.358 N/A N/A a.7.7 BAG domain
View Download 0.358 N/A N/A a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.358 N/A N/A a.25.1 Ferritin-like
View Download 0.354 N/A N/A a.2.7 tRNA-binding arm
View Download 0.351 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.345 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.342 N/A N/A a.29.2 Bromodomain
View Download 0.341 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.339 N/A N/A a.2.7 tRNA-binding arm
View Download 0.336 N/A N/A a.2.7 tRNA-binding arm
View Download 0.329 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.329 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.328 N/A N/A a.62.1 Hepatitis B viral capsid (hbcag)
View Download 0.327 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.327 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.325 N/A N/A a.26.1 4-helical cytokines
View Download 0.320 N/A N/A a.87.1 DBL homology domain (DH-domain)
View Download 0.320 N/A N/A a.29.2 Bromodomain
View Download 0.318 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.316 N/A N/A a.26.1 4-helical cytokines
View Download 0.308 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.308 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.308 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.307 N/A N/A a.26.1 4-helical cytokines
View Download 0.306 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.306 N/A N/A d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.306 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.306 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.303 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.299 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.294 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.290 N/A N/A a.25.1 Ferritin-like
View Download 0.289 N/A N/A a.7.1 Spectrin repeat
View Download 0.284 N/A N/A a.24.1 Apolipoprotein
View Download 0.283 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.281 N/A N/A a.47.2 t-snare proteins
View Download 0.280 N/A N/A a.7.1 Spectrin repeat
View Download 0.280 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.278 N/A N/A a.7.1 Spectrin repeat
View Download 0.278 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.274 N/A N/A a.90.1 Transcription factor STAT-4 N-domain
View Download 0.273 N/A N/A a.29.2 Bromodomain
View Download 0.272 N/A N/A f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.272 N/A N/A a.2.7 tRNA-binding arm
View Download 0.271 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.271 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.268 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.264 N/A N/A a.47.2 t-snare proteins
View Download 0.262 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.262 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.262 N/A N/A d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.262 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.259 N/A N/A a.118.1 ARM repeat
View Download 0.258 N/A N/A a.24.11 Bacterial GAP domain
View Download 0.256 N/A N/A a.24.3 Cytochromes
View Download 0.255 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.254 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.253 N/A N/A d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.253 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.253 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.250 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.249 N/A N/A a.6.1 Putative DNA-binding domain
View Download 0.248 N/A N/A a.18.1 T4 endonuclease V
View Download 0.247 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.247 N/A N/A a.24.3 Cytochromes
View Download 0.245 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.245 N/A N/A a.26.1 4-helical cytokines
View Download 0.245 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.243 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.243 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.242 N/A N/A a.18.1 T4 endonuclease V
View Download 0.242 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.242 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.242 N/A N/A d.58.21 Molybdenum cofactor biosynthesis protein C, MoaC
View Download 0.241 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.240 N/A N/A a.47.2 t-snare proteins
View Download 0.240 N/A N/A a.26.1 4-helical cytokines
View Download 0.234 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.232 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.228 N/A N/A a.25.1 Ferritin-like
View Download 0.228 N/A N/A f.1.3 delta-Endotoxin (insectocide), N-terminal domain
View Download 0.227 N/A N/A f.17.2 Cytochrome c oxidase subunit II-like, transmembrane region
View Download 0.227 N/A N/A a.26.1 4-helical cytokines
View Download 0.227 N/A N/A f.17.2 Cytochrome c oxidase subunit II-like, transmembrane region
View Download 0.226 N/A N/A a.19.1 Fertilization protein
View Download 0.225 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.225 N/A N/A a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.223 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.223 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.223 N/A N/A a.25.1 Ferritin-like
View Download 0.223 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.221 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.221 N/A N/A d.19.1 MHC antigen-recognition domain
View Download 0.220 N/A N/A d.173.1 Methionine synthase activation domain-like
View Download 0.219 N/A N/A a.26.1 4-helical cytokines
View Download 0.219 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.217 N/A N/A a.7.1 Spectrin repeat
View Download 0.216 N/A N/A a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.214 N/A N/A a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.214 N/A N/A a.47.2 t-snare proteins
View Download 0.213 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.211 N/A N/A f.1.3 delta-Endotoxin (insectocide), N-terminal domain
View Download 0.209 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.209 N/A N/A a.118.8 TPR-like
View Download 0.209 N/A N/A a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.208 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.205 N/A N/A a.24.12 Outer surface protein C (OspC)
View Download 0.205 N/A N/A a.47.2 t-snare proteins
View Download 0.205 N/A N/A g.52.1 Inhibitor of apoptosis (IAP) repeat
View Download 0.205 N/A N/A i.1.1 Ribosome and ribosomal fragments
View Download 0.205 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.204 N/A N/A d.81.1 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
View Download 0.202 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.200 N/A N/A a.24.14 FAT domain of focal adhesion kinase

Predicted Domain #6
Region A:
Residues: [748-963]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVISLLSTYG LYFFSSLMYL DPWHMFTSSI QYFLTLPAFT CTLQIFAFCN THDVSWGTKG  60
   61 STQESKQLSK AIVVQGPDGK QIVETDWPQE VDKKFLEIKS RLKEPEFEES SGNEKQSKND 120
  121 YYRDIRTRIV MIWMLSNLIL IMSIIQVFTP QDTDNGYLIF ILWSVAALAA FRVVGSMAFL 180
  181 FMKYLRIIVS YRNKVEGSGS WEVSKLDLPN VFHKKG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle