YRC Public Data Repository - Protein Structure Prediction

Protein:	FUR4
Organism:	Saccharomyces cerevisiae
Length:	633 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUR4.

Description	E-value	Query Range	Subject Range
gi\|190408808 - gi\|190408808\|gb\|EDV12073.1\| uracil permease [Saccharomyces cerevisiae RM11-1a] gi\|207347785 - gi\|207347785\|gb\|EDZ73852.1\| YBR021Wp-like protein [Saccharomyces cerevisiae AWRI1631] FUR4 - Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels ... gi\|151946414 - gi\|151946414\|gb\|EDN64636.1\| uracil permease [Saccharomyces cerevisiae YJM789] FUR4_YEAST - Uracil permease OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FUR4 PE=3 SV=2	0.0	[1..633]	[1..633]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	0.0	[1..633]	[1..633]
YEME_SCHPO - Uncharacterized permease C29B12.14c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC29... SPAC29B12.14c - purine transporter	1.0E-96	[76..628]	[19..550]
fur4 - uracil permease FUR4_SCHPO - Uracil permease OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fur4 PE=1 SV=2	2.0E-92	[56..618]	[3..542]

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Predicted Domain #1

Region A:
Residues: [1-92]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDNLSLHLS GSSKRLNSRQ LMESSNETFA PNNVDLEKEY KSSQSNITTE VYEASSFEEK  60
   61 VSSEKPQYSS FWKKIYYEYV VVDKSILGVS IL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [93-578]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSFMYNQDLK PVEKERRVWS WYNYCYFWLA ECFNINTWQI AATGLQLGLN WWQCWITIWI  60
   61 GYGFVGAFVV LASRVGSAYH LSFPISSRAS FGIFFSLWPV INRVVMAIVW YSVQAYIAAT 120
  121 PVSLMLKSIF GKDLQDKIPD HFGSPNATTY EFMCFFIFWA ASLPFLLVPP HKIRHLFTVK 180
  181 AVLVPFASFG FLIWAIRRAH GRIALGSLTD VQPHGSAFSW AFLRSLMGCM ANFSTMVINA 240
  241 PDFSRFSKNP NSALWSQLVC IPFLFSITCL IGILVTAAGY EIYGINYWSP LDVLEKFLQT 300
  301 TYNKGTRAGV FLISFVFAVA QLGTNISANS LSCGTDMSAI FPKFINIKRG SLFCAAMALC 360
  361 ICPWNLMATS SKFTMALSAY AIFLSSIAGV VCSDYFVVRR GYIKLTHIYS HQKGSFYMYG 420
  421 NRFGINWRAL AAYLCGVAPC LPGFIAEVGA PAIKVSDGAM KLYYLSYWVG YGLSFSSYTA 480
  481 LCYFFP

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	248.49485
Match:	PF02133
Description:	Permease for cytosine/purines, uracil, thiamine, allantoin

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [579-633]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VPGCPVNNII KDKGWFQRWA NVDDFEEEWK DTIERDDLVD DNISVYEHEH EKTFI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits