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View Structure Prediction Details

Protein: GRX7
Organism: Saccharomyces cerevisiae
Length: 203 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GRX7.

Description E-value Query
Range
Subject
Range
GLRX7_YEAST - Monothiol glutaredoxin-7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GRX7 PE=1 SV=1
GRX7 - Cis-golgi localized monothiol glutaredoxin; more similar in activity to dithiol than other monothiol...
6.0E-56 [1..203] [1..203]
gi|2724050, gi|2... - gi|2724056|gb|AAB92658.1| glutaredoxin type I [Fritillaria agrestis], gi|2724054|gb|AAB92657.1| glut...
4.0E-32 [87..192] [2..104]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-31 [87..195] [2..107]
gi|116310771, gi... - gi|125548975|gb|EAY94797.1| hypothetical protein OsI_16580 [Oryza sativa Indica Group], gi|116310771...
GRXC6_ORYSA, GLR... - Glutaredoxin-C6 (Glutaredoxin-C2 homolog 1) - Oryza sativa (Rice), (P55142) Glutaredoxin
GRXC6_ORYSJ - Glutaredoxin-C6 OS=Oryza sativa subsp. japonica GN=GRXC6 PE=1 SV=2
4.0E-31 [87..195] [2..107]
GRXC2_ARATH - Glutaredoxin-C2 OS=Arabidopsis thaliana GN=GRXC2 PE=2 SV=1
8.0E-31 [87..191] [2..103]
GLRX2 - glutaredoxin 2
8.0E-31 [48..196] [16..162]
gi|65811 - pir||GDPG glutaredoxin - pig
GLRX1_PIG - Glutaredoxin-1 OS=Sus scrofa GN=GLRX PE=1 SV=2
2.0E-30 [87..191] [2..106]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIVINKRNV RVLVITNLLL IVVFFVLRNS NASVNESITT HHPDSLVTFD NSGNAPGTHQ  60
   61 SVHDTVNTQD KEAEEVDKNS G

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.460 a.4.1 Homeodomain-like
View Download 0.460 a.77.1 DEATH domain
View Download 0.465 f.14.1 Voltage-gated potassium channels
View Download 0.464 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.400 d.237.1 Hypothetical protein YjiA, C-terminal domain
View Download 0.397 a.77.1 DEATH domain
View Download 0.390 d.15.1 Ubiquitin-like
View Download 0.383 b.11.1 gamma-Crystallin-like
View Download 0.355 a.77.1 DEATH domain
View Download 0.347 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.338 d.74.2 C-terminal domain of arginine repressor
View Download 0.336 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.335 f.14.1 Voltage-gated potassium channels
View Download 0.333 f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.331 b.71.1 Glycosyl hydrolase domain
View Download 0.328 d.58.3 Protease propeptides/inhibitors
View Download 0.305 a.76.1 Iron-dependent represor protein, dimerization domain
View Download 0.303 i.1.1 Ribosome and ribosomal fragments
View Download 0.293 a.36.1 Signal peptide-binding domain
View Download 0.282 a.77.1 DEATH domain
View Download 0.276 a.46.1 Methionine synthase domain
View Download 0.274 d.137.1 Monooxygenase (hydroxylase) regulatory protein
View Download 0.273 a.4.1 Homeodomain-like
View Download 0.271 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.260 d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.252 a.50.1 Anaphylotoxins (complement system)
View Download 0.240 a.4.1 Homeodomain-like
View Download 0.236 d.58.3 Protease propeptides/inhibitors
View Download 0.234 a.138.1 Multiheme cytochromes
View Download 0.219 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.209 d.137.1 Monooxygenase (hydroxylase) regulatory protein
View Download 0.206 d.10.1 DNA-binding domain

Predicted Domain #2
Region A:
Residues: [82-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAEFDAAAEY NKIMEQSPMI VFSKTGCPYS KKLKALLTNS YTFSPSYYVV ELDRHEHTKE  60
   61 LQDQIEKVTG RRTVPNVIIG GTSRGGYTEI AELHKNDELL DSFKKWSDGA FTVKANSQSE 120
  121 SA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 139.0
Match: 1b4qA_
Description: Glutaredoxin (Grx, thioltransferase)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle