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View Structure Prediction Details

Protein: SAS3
Organism: Saccharomyces cerevisiae
Length: 831 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAS3.

Description E-value Query
Range
Subject
Range
SAS3 - Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in ...
SAS3_YEAST - Histone acetyltransferase SAS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SAS3 PE=1...
0.0 [1..831] [1..831]
gi|8567376, gi|6... - gi|8567376|ref|NP_059507.1| MYST histone acetyltransferase monocytic leukemia 4 [Mus musculus], gi|6...
0.0 [196..576] [339..701]
gi|162461408, gi... - gi|194702096|gb|ACF85132.1| unknown [Zea mays], gi|17017390|gb|AAL33649.1|AF440220_1 histone aceytl-...
0.0 [215..575] [127..441]
gi|6912512, gi|6... - gi|6912512|ref|NP_036462.1| MYST histone acetyltransferase (monocytic leukemia) 4 [Homo sapiens], gi...
0.0 [195..576] [641..992]
KAT6B_MACFA - Histone acetyltransferase KAT6B OS=Macaca fascicularis GN=KAT6B PE=2 SV=1
0.0 [233..576] [388..700]
MYST2_ARATH - Histone acetyltransferase of the MYST family 2 OS=Arabidopsis thaliana GN=HAM2 PE=1 SV=1
0.0 [215..575] [129..442]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [215..575] [117..430]

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Predicted Domain #1
Region A:
Residues: [1-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLTANDESP KPKKNALLKN LEIDDLIHSQ FVRSDTNGHR TTRRLFNSDA SISHRIRGSV  60
   61 RSDKGLNKIK KGLISQQSKL ASENSSQNIV NRDNKMGAVS FPIIEPNIEV SEELKVRIKY 120
  121 DSIKFFNFER LISKSSVIAP LVNKNITSSG PLIGFQRRVN RLKQTWDLAT ENMEYPYSSD 180
  181 NTPFRDNDSW QWYVPYGGTI KKMKDFSTKR TLPTWEDKIK FLTFLENSKS ATYINGNVSL 240
  241 CN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [243-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HNETDQENED RKKRKGKVPR IKNKVWFSQI EYIVLRNYEI KPWYTSPFPE HINQNKMVFI  60
   61 CEFCLKYMTS RYTFYRHQLK C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 730.0
Match: 1fy7A_
Description: Histone acetyltransferase ESA1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [324-428]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTFKPPGNEI YRDGKLSVWE IDGRENVLYC QNLCLLAKCF INSKTLYYDV EPFIFYILTE  60
   61 REDTENHPYQ NAAKFHFVGY FSKEKFNSND YNLSCILTLP IYQRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 730.0
Match: 1fy7A_
Description: Histone acetyltransferase ESA1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [429-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYGQFLMEFS YLLSRKESKF GTPEKPLSDL GLLTYR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [561-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPRVKYDKLL WEPIILGPSF GINGMMN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 730.0
Match: 1fy7A_
Description: Histone acetyltransferase ESA1
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [465-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFWKIKCAEV LLKLRDSARR RSNNKNEDTF QQVSLNDIAK LTGMIPTDVV FGLEQLQVLY  60
   61 RHKTRSLSSL DDFNYIIKID SWNRIENIYK TWSSKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 730.0
Match: 1fy7A_
Description: Histone acetyltransferase ESA1
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [588-831]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEPTALADEA LTNETMAPVI SNNTHIENYN NSRAHNKRRR RRRRSSEHKT SKLHVNNIIE  60
   61 PEVPATDFFE DTVSSLTEYM CDYKNTNNDR LIYQAEKRVL ESIHDRKGIP RSKFSTETHW 120
  121 ELCFTIKNSE TPLGNHAARR NDTGISSLEQ DEVENDVDTE LYVGENAKED EDEDEDFTLD 180
  181 DDIEDEQISE ENDEEEDTYE EDSDDDEDGK RKGQEQDEND IESHIRKERV RKRRKITLIE 240
  241 DDEE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle