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View Structure Prediction Details

Protein: CLN3
Organism: Saccharomyces cerevisiae
Length: 580 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLN3.

Description E-value Query
Range
Subject
Range
CLN3 - G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase t...
CG13_YEAST - G1/S-specific cyclin CLN3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLN3 PE=1 SV=2
0.0 [1..580] [1..580]
CCNB2_RANJA - G2/mitotic-specific cyclin-B2 OS=Rana japonica GN=CCNB2 PE=2 SV=1
1.0E-91 [7..351] [60..391]
gi|1835260 - gi|1835260|emb|CAA99990.1| mitotic cyclin [Sesbania rostrata]
2.0E-91 [2..349] [129..445]
gi|157423093, gi... - gi|7328938|dbj|BAA92876.1| cyclin B1 [Danio rerio], gi|31323423|gb|AAP47013.1| cyclin-B [Danio rerio...
7.0E-91 [1..350] [65..398]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-90 [10..332] [108..404]
gi|7271222 - gi|7271222|emb|CAB81558.1| cyclin B1 [Nicotiana tabacum]
3.0E-90 [10..348] [108..424]
gi|13605768 - gi|13605768|gb|AAK32876.1| cyclin B2 [Rana dybowskii]
3.0E-90 [7..351] [60..393]
CCNB1_SOYBN - G2/mitotic-specific cyclin S13-6 OS=Glycine max PE=2 SV=1
2.0E-89 [3..351] [135..453]
gi|9082247 - gi|9082247|gb|AAF82779.1| cyclin B [Carassius auratus gibelio]
4.0E-89 [1..350] [64..397]

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Predicted Domain #1
Region A:
Residues: [1-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAILKDTIIR YANARYATAS GTSTATAASV SAASCPNLPL LLQKRRAIAS AKSKNPNLVK  60
   61 RELQAHHSAI SEYNNDQLDH YFR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [210-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFDSYIDIFL FQSTSPLSPG VVLSAPLEAF IQQKLALLNN AAGTAINKSS SSQGPSLNIN  60
   61 EIKLGAIMLC ELASFNLELS FKYDRSLIAL GAINLIKLSL NYYNSNLWEN INLALEENCQ 120
  121 DLDIKLSEIS NTLLDIAMDQ NS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.39794
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [84-209]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSHTERPLYN LTNFNSQPQV NPKMRFLIFD FIMYCHTRLN LSTSTLFLTF TILDKYSSRF  60
   61 IIKSYNYQLL SLTALWISSK FWDSKNRMAT LKVLQNLCCN QYSIKQFTTM EMHLFKSLDW 120
  121 SICQSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.39794
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [352-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FPSSFKSKYL NSNKTSLAKS LLDALQNYCI QLKLEEFYRS QELETMYNTI FAQSFDSDSL  60
   61 TCVYSNATTP KSATVSSAAT DYFSDHTHLR RLTKDSISPP FAFTPTSSSS SPSPFNSPYK 120
  121 TSSSMTTPDS ASHHSHSGSF SSTQNSFKRS LSIPQNSSIF WPSPLTPTTP SLMSNRKLLQ 180
  181 NLSVRSKRLF PVRPMATAHP CSAPTQLKKR STSSVDCDFN DSSNLKKTR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle