YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|83586370, gi\|...
Organism:	Escherichia coli 101-1
Length:	483 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|83586370, gi|....

Description	E-value	Query Range	Subject Range
gi\|157080292, gi... - gi\|75189408\|ref\|ZP_00702675.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|209910808, gi... - gi\|209917549\|ref\|YP_002291633.1\| 2-methylcitrate dehydratase [Escherichia coli SE11], gi\|209910808\|d... gi\|218552900, gi... - gi\|218552900\|ref\|YP_002385813.1\| 2-methylcitrate dehydratase [Escherichia coli IAI1], gi\|218359668\|e... gi\|218693797, gi... - gi\|218693797\|ref\|YP_002401464.1\| 2-methylcitrate dehydratase [Escherichia coli 55989], gi\|218350529\|... gi\|192928984, gi... - gi\|75257640\|ref\|ZP_00729131.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|191165745, gi... - gi\|75231107\|ref\|ZP_00717529.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|194427548, gi... - gi\|75211136\|ref\|ZP_00711243.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|157159851, gi... - gi\|75194558\|ref\|ZP_00704628.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E...	572.0	[0..1]	[483..1]
gi\|75238481, gi\|... - gi\|75238481\|ref\|ZP_00722475.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E... gi\|110640613, gi... - gi\|110640613\|ref\|YP_668341.1\| 2-methylcitrate dehydratase [Escherichia coli 536], gi\|110342205\|gb\|AB...	572.0	[0..1]	[483..1]
gi\|192958035, gi... - gi\|75237259\|ref\|ZP_00721306.1\| COG2079: Uncharacterized protein involved in propionate catabolism [E...	572.0	[0..1]	[483..1]
gi\|91209411, gi\|... - gi\|91209411\|ref\|YP_539397.1\| 2-methylcitrate dehydratase [Escherichia coli UTI89], gi\|91070985\|gb\|AB... gi\|117622616, gi... - gi\|117622616\|ref\|YP_851529.1\| 2-methylcitrate dehydratase [Escherichia coli APEC O1], gi\|115511740\|g... gi\|237707663, gi... - gi\|237707663\|ref\|ZP_04538144.1\| 2-methylcitrate dehydratase [Escherichia sp. 3_2_53FAA], gi\|22689887... gi\|26246349, gi\|... - gi\|26246349\|ref\|NP_752388.1\| 2-methylcitrate dehydratase [Escherichia coli CFT073], gi\|26106747\|gb\|A... gi\|227884648, gi... - gi\|227884648\|ref\|ZP_04002453.1\| 2-methylcitrate dehydratase [Escherichia coli 83972], gi\|227838383\|g... gi\|218557262, gi... - gi\|218557262\|ref\|YP_002390175.1\| 2-methylcitrate dehydratase [Escherichia coli S88], gi\|218364031\|em...	571.0	[0..1]	[483..1]
gi\|83725260, gi\|... - gi\|83748074\|ref\|ZP_00945103.1\| 2-methylcitrate dehydratase / 2-methylisocitrate dehydratase [Ralston... gi\|206594188, gi... - gi\|207742794\|ref\|YP_002259186.1\| prpd protein [Ralstonia solanacearum IPO1609], gi\|206594188\|emb\|CAQ...	570.0	[0..1]	[483..1]
gi\|13359844, gi\|... - gi\|15829641\|ref\|NP_308414.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. Sakai], gi\|1... gi\|209159921, gi... - gi\|209398521\|ref\|YP_002268971.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4115],... gi\|217322854, gi... - gi\|217326633\|ref\|ZP_03442717.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. TW14588],... gi\|195937833 - gi\|195937833\|ref\|ZP_03083215.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4024] gi\|208728101, gi... - gi\|208808300\|ref\|ZP_03250637.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4206], ... gi\|208732387, gi... - gi\|208815739\|ref\|ZP_03256918.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4045], ... gi\|254791512, gi... - gi\|254791512\|ref\|YP_003076349.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. TW14359]... gi\|208823186, gi... - gi\|208823186\|ref\|ZP_03263504.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4042], ... gi\|187769073, gi... - gi\|187769073\|gb\|EDU32917.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4196], gi\|1... gi\|188999853, gi... - gi\|188999853\|gb\|EDU68839.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4076], gi\|1... gi\|189371708, gi... - gi\|189371708\|gb\|EDU90124.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC869], gi\|16... gi\|189377830, gi... - gi\|189377830\|gb\|EDU96246.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC508], gi\|16... gi\|188016477, gi... - gi\|188016477\|gb\|EDU54599.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4113], gi\|1... gi\|168755912, gi... - gi\|189356959\|gb\|EDU75378.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4401], gi\|1... gi\|168762004, gi... - gi\|189367672\|gb\|EDU86088.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4501], gi\|1... gi\|168769713, gi... - gi\|189361316\|gb\|EDU79735.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4486], gi\|1... PRPD_ECO57 - 2-methylcitrate dehydratase OS=Escherichia coli O157:H7 GN=prpD PE=3 SV=3 gi\|209744756, gi... - pir\|\|F85527 hypothetical protein prpD [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15800062, gi\|... - gi\|15800062\|ref\|NP_286074.1\| 2-methylcitrate dehydratase [Escherichia coli O157:H7 EDL933], gi\|12513...	570.0	[0..1]	[483..1]
gi\|48784618, gi\|... - gi\|91777235\|ref\|YP_552443.1\| 2-methylcitrate dehydratase [Burkholderia xenovorans LB400], gi\|9168989...	569.0	[0..1]	[483..1]
gi\|36786848, gi\|... - gi\|37527413\|ref\|NP_930757.1\| 2-methylcitrate dehydratase [Photorhabdus luminescens subsp. laumondii ...	567.0	[0..1]	[483..1]
PRPD_SALTY - 2-methylcitrate dehydratase OS=Salmonella typhimurium GN=prpD PE=3 SV=2 PRPD_SALTY - 2-methylcitrate dehydratase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=prpD ... PRPD_SALTY - 2-methylcitrate dehydratase OS=Salmonella typhimurium GN=prpD PE=3 SV=2 gi\|205329549, gi... - gi\|205329549\|gb\|EDZ16313.1\| 2-methylcitrate dehydratase [Salmonella enterica subsp. enterica serovar... gi\|168819032, gi... - gi\|205344121\|gb\|EDZ30885.1\| 2-methylcitrate dehydratase [Salmonella enterica subsp. enterica serovar... lcl\|NC_016856.1_... - [gene=prpD] [protein=2-methylcitrate dehydratase] [protein_id=YP_005236049.1] [location=420889..4223...	567.0	[0..1]	[483..1]
gi\|197363395, gi... - gi\|197363395\|ref\|YP_002143032.1\| 2-methylcitrate dehydratase [Salmonella enterica subsp. enterica se... gi\|56128731, gi\|... - gi\|56414474\|ref\|YP_151549.1\| 2-methylcitrate dehydratase [Salmonella enterica subsp. enterica serova...	567.0	[0..1]	[483..1]

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Predicted Domain #1

Region A:
Residues: [1-483]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAQINNIRP EFDREIVDIV DYVMNYEISS KVAYDTAHYC LLDTLGCGLE ALEYPACKKL  60
   61 LGPIVPGTVV PNGVRVPGTQ FQLDPVQAAF NIGAMIRWLD FNDTWLAAEW GHPSDNLGGI 120
  121 LATADWLSRN AVASGKAPLT MKQVLTAMIK AHEIQGCIAL ENSFNRVGLD HVLLVKVAST 180
  181 AVVAEMLGLT REEILNAVSL AWVDGQSLRT YRHAPNTGTR KSWAAGDATS RAVRLALMAK 240
  241 TGEMGYPSAL TAPVWGFYDV SFKGESFRFQ RPYGSYVMEN VLFKISFPAE FHSQTAVEAA 300
  301 MTLYEQMQAA GKTAADIEKV TIRTHEACIR IIDKKGPLNN PADRDHCIQY MVAIPLLFGR 360
  361 LTAADYEDNV AQDKRIDALR EKINCFEDPA FTADYHDPEK RAIANAITLE FTDGTRFEEV 420
  421 VVEYPIGHAR RRQDGIPKLV DKFKINLARQ FPTRQQQRIL EVSLDRARLE QMPVNEYLDL 480
  481 YVI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	164.0
Match:	1szqA
Description:	Crystal Structure of 2-methylcitrate dehydratase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
2-methylcitrate dehydratase activity	2.63183683070179	bayes_pls_golite062009
catalytic activity	0.534516847146079	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: